Bu araştırmada, yaşlılarda ilaç kullanım hataları konusunda yayımlanmış olan çalışmaların gözden geçirilmesi ve elde edilen verilerin sistematik biçimde incelenmesi amaçlanmıştır. Çalışma, Ocak 2015 ve Ocak 2020 tarihleri arasında, 'Google Scholar, Google Akademik, PubMed, Web of Science, Cochrane Library, ClinicalKey, Scopus, CINAHL/MEDLINE' veri tabanlarında ve araştırmacılar tarafından belirlenen anahtar kelimeler ile ulaşılan ulusal ve uluslararası çalışmalar taranarak gerçekleştirilmiştir. Yaşlılarda ilaç kullanım hatalarına ilişkin verileri içeren, yayın dili Türkçe ve İngilizce olan, son 5 yılda yayımlanmış ve tam metnine ulaşılabilen makaleler seçilmiştir. Bu makalelerden araştırma kriterlerini karşılayan toplam 9 çalışma, sistematik derlemenin örneklemini oluşturmuştur. Çalışmaya dâhil edilen 9 araştırmanın 7'si tanımlayıcı, 1'i tanımlayıcı-kesitsel tipte, 1'i de nitel araştırma tasarımına sahiptir. Çalışmalarda araştırmacılar tarafından literatür doğrultusunda geliştirilen anket formları, ''Akılcı İlaç Kullanımına Yönelik Bilgi ve Davranışların Değerlendirilmesi Anketi'' ile derinlemesine yarı yapılandırılmış görüşme tekniği kullanılmıştır. Değerlendirmeye alınan çalışmaların sonuçlarına göre yaşlıların en çok yapmış olduğu ilaç kullanım hatalarının; ilaçlarını zamanında kullanmama, reçetesiz ilaç kullanma/ yakın tavsiyesi ile ilaç kullanma ve kendi kararı ile ilaçlarını kullanmayı bırakma olarak tespit edilmiştir. Diğer ilaç kullanım hataları ise ilaçlarını yanlış dozda alma, ilaçlarını almayı unutma, eski reçeteden arta kalan ilaçları kullanmak üzere saklama, ilaçlarını karıştırma, ilaçların son kullanma tarihine dikkat etmeme, ilaç doz formunda değişiklik yapma ve kullanmadığı ilaçları arkadaşlarına veya komşularına verme şeklindedir. Bu sistematik derleme sonucunda yaşlı bireylerin en çok; ilaçlarını zamanında kullanmama, reçetesiz ilaç kullanma/yakın tavsiyesi ile ilaç kullanma ve kendi kararı ile ilaçlarını kullanmayı bırakma şeklinde hatalar yaptığı sonucuna varılmıştır.
Anahtar Kelimeler: İlaç kullanım hataları; sistematik derleme; yaşlı
In this study, it is aimed to review the published studies on medication use errors in elderly and to systematically analyze the obtained data. This study was carried out by scanning national and international studies between January 2015 and January 2020, in databases of ''Google Scholar, PubMed, Web of Science, Cochrane Library, ClinicalKey, Scopus, CINAHL/MEDLINE'' and with the keywords determined by the researchers. Articles containing data on medication use errors in elderly, published in Turkish and English, published in the last 5 years and whose full text can be accessed were selected. A total of 9 studies that met the research criteria from these articles constituted the sample of the systematic review. Of the 9 studies included in the study, 7 have descriptive design, 1 has descriptivecross-sectional design and 1 has qualitative research design. In the studies, was used the questionnaire forms developed by the researchers in line with the literature, ''The Questionnaire for Evaluating Information and Behaviors Regarding Rational Drug Use'' with in-depth semi-structured interview technique. According to the results of the studies, the most common medication use errors made by elderly are; not to use their medicines on time, to use over-the-counter medication/ to use medications on the advice of relatives and to stop using their medicines at their own decision. Other medication use errors are; taking the medication in wrong dose, forgetting to take medication, storing the medicines left over from the old prescription, mixing the medicines, not paying attention to the expiration date of the medicines, making changes to the medication dosage form and giving the medicines to friends or neighbors. As a result of this systematic review, most of the elderly individuals; It was concluded that he did not make use of his medicines on time, use medications without a prescription/ use medications with close advice and stop using his own medications at his own decision.
Keywords: Medication use errors; systematic review; elderly
- Şimşek N, Öztürk GK, Yüceler Kaçmaz H. [Old Age and Loneliness]. The Journal of International Social Research. 2018;11(58):496-9.[Crossref]
- Hodgson R, Kennedy BK, Masliah E, Scearce-Levie K, Tate B, Venkateswaran A, et al. Aging: therapeutics for a healthy future. Neurosci Biobehav Rev. 2020;108:453-8.[Crossref] [PubMed]
- Turkish Language Institution Dictionaries, (Erişim tarihi: 8.1.2020)[Link]
- Geneva: World Health Organization, World report on ageing and health. 2015. (Erişim tarihi: 08.01.2020)[Link]
- Baltacioglu H, Eroglu O, Coskun F. An investigation of inappropriate medication use and dangerous drug combinations in elderly patients with polypharmacy. Medical Science and Discovery. 2018;5(8):295-302.[Crossref]
- Monteiro L, Maricoto T, Solha IS, Monteiro-Soares M, Martins C. Computerised decision to reduce inappropriate medication in the elderly: a systematic review with meta-analysis protocol. BMJ Open. 2018;8(1):e018988.[Crossref] [PubMed] [PMC]
- Gümüştakım RŞ, Başer DA. [Multiple drug use in elderly in primary care: An example of rural field]. Turkish Journal of Family Practice. 2019;23(1):2-8.[Crossref]
- Bozkurt E, Parlar A, Arslan SO. [Investigation of inappropriate drug use in older patients and polifarmacy presence]. Journal of Health Sciences of Adıyaman University. 2019;5(1):1254-66.[Crossref]
- Kasar KS, Karadakovan A. [Elderly individuals investigation of antihypertensive drugs use error]. Journal of Cardiovascular Nursing. 2017;8(15):20-7.[Crossref]
- Mortazavi SS, Shati M, Khankeh HR, Ahmadi F, Mehravaran S, Malakouti SK. Self-medication among the elderly in Iran: a content analysis study. BMC Geriatr. 2017;17(1):198.[Crossref] [PubMed] [PMC]
- Öztaş Ö, Korkmaz Aslan G. [The elderly medication use behaviors that cause medication non-compliance and its association with their health literacy levels]. Journal of Hacettepe University Faculty of Nursing. 2019;6(3):132-40.[Link]
- Ünüvar S, Bayrak H, Aktay G. [Evaluation of multiple drug use in the elderly]. General Medical Journal. 2019;29(2):55-9.[Link]
- Sah AK, Jha RK, Sah P, Basnet S. Potentially inappropriate prescribing in elderly population: A study in medicine out-patient department. Journal of College of Medical Sciences-Nepal. 2017;13(1):197-202.[Crossref]
- Sakr S, Hallit S, Haddad M, Khabbaz LR. Assessment of potentially inappropriate medications in elderly according to Beers 2015 and STOPP criteria and their association with treatment satisfaction. Arch Gerontol Geriatr. 2018;78:132-8.[Crossref] [PubMed]
- Prasert V, Akazawa M, Shono A, Chanjaruporn F, Ploylearmsang C, Muangyim K, et al. Applying the Lists of Risk Drugs for Thai Elderly (LRDTE) as a mechanism to account for patient age and medicine severity in assessing potentially inappropriate medication use. Res Social Adm Pharm. 2018;14(5):451-8.[Crossref] [PubMed]
- Saboor M, Kamrani AA, Momtaz YA, Sahaf R. Prevalence and associated factors of potentially inappropriate medications among Iranian older adults. Med Glas (Zenica). 2019;16(1):121-7.[PubMed]
- Curtin D, Dukelow T, James K, O'Donnell D, O'Mahony D, Gallagher P. Deprescribing in multi-morbid older people with polypharmacy: agreement between STOPPFrail explicit criteria and gold standard deprescribing using 100 standardized clinical cases. Eur J Clin Pharmacol. 2019;75(3):427-32.[Crossref] [PubMed]
- Demirarslan E. [Characteristics that way affect knowladge and ımplementations of older patients' medicine usage in surgical units]. Kastamonu Health Academy. 2016;(1):18-38.[Link]
- Güneş D, Kıyak E.[The knowledge of the elderly on drug use and the evaluation of the factors affecting their knowledge level]. Journal of Continuing Medical Education. 2017;26(2):66-74.[Link]
- Yılmazel G, Büyükkayacı Duman N. [Polypharmacy and comorbidities among elderly women]. Journal of Continuing Medical Education. 2018;27(2):80-5.[Link]
- Özen B, Kaya Erten Z, Bülbül T. [Intergenerational rational drug use]. Journal of Health Sciences. 2018;27:199-204.[Link]
- Benlier N, Şahin B, Göğer ME, Sezal E, Sankır D, Pamukiçi AK, et al. [Rational drug use in geriatric patients in the county of Gaziantep]. Journal of Geriatric Science. 2019;2(2):30-5.[Link]
- Akkoca AN, Soylu Özler G, Yengil E, Özler S, Demirkıran G. [Evaluation of geriatric patients' knowledge and behavior about drug usage]. Smyrna Medical Journal. 2014:1-6.[Link]
- Baruth JM, Gentry MT, Rummans TA, Miller DM, Burton MC. Polypharmacy in older adults: the role of the multidisciplinary team. Hosp Pract (1995). 2020;48(sup1):56-62.[Crossref] [PubMed]
- Beuscart JB, Petit S, Gautier S, Wierre P, Balcaen T, Lefebvre JM, et al. Polypharmacy in older patients: identifying the need for support by a community pharmacist. BMC Geriatr. 2019;19(1):277.[Crossref] [PubMed] [PMC]
- Demirbağ BC, Timur M. [The knowledge, attitude and behavior related to using drugs reflected by the group of elderly]. Ankara Journal of Health Sciences. 2012;11(1):1-8.[Link]
- Kasar KS, Kızılcı S. [Oral antidiabetic drugs user errors and influencing factors]. Gümüşhane University Journal of Health Sciences, 2017;6(3):128-37.[Link]
- Akkuş Y, Karatay G. [Knowledge and behaviovur about drug usage of people aged over 60 and live in Kars]. Journal of Tübav Science. 2011;4(3):214-20.[Link]
- Arpacı F, Açıkel CH, Şimşek I. [Attitudes of drug use of an elderly population living in Ankara]. TAF Prev Med Bull. 2008;7(6):515-22.[Link]
- Dedeli Caydam Ö, Karadakovan A. [Investigation of complementary and alternative medicine practice and drug use in the elderly]. Spatula DD. 2011;1(1):23-32.[Crossref]
- Ünsal A, Demir G, Çoban Özkan A, Görol Arslan G. [The prevalance of chronic disease and drug use of the olders living in nursing home]. Journal of Adnan Menderes University Medical Faculty. 2011;12(3):5-10.[Link]
- Mhatre SK, Sansgiry SS. Assessing a conceptual model of over-the-counter medication misuse, adverse drug events and health-related quality of life in an elderly population. Geriatr Gerontol Int. 2016;16(1):103-10.[Crossref] [PubMed]
- Stone JA, Lester CA, Aboneh EA, Phelan CH, Welch LL, Chui MA. A preliminary examination of over-the-counter medication misuse rates in older adults. Res Social Adm Pharm. 2017;13(1):187-92.[Crossref] [PubMed] [PMC]
- Varlı M, Bahşi R, Doğan Ş, Uysal H, Subaşı Ş, Toper M, et al. [Nonprescription product use among geriatric outpatients]. Ankara Medical Journal. 2017;17(4):226-34.[Link]
- Bilgener E, Özçelikay, G. [Rational drug use in geriatric women]. Turkiye Klinikleri Obstetric-Women's Health and Diseases Nursing-Special Topics. 2019;5(1):62-8.[Link]
- Taşkın Şayir Ç, Aslan Karaoğlu S, Evcik Toprak D. [Evaluation of polypharmacy and complementary therapy use in patients ≥65 years, attending to Family Medicine Outpatient Clinic of fiiflli Etfal Training and Research Hospital]. Turkish Journal of Family Practice. 2014;18(1):35-41.[Crossref]
- Özdemir Ö, Akyüz A, Doruk H. [Compliance with drug treatment in geriatric patients with hypertension]. Medical Journal of Bakırköy. 2016;12(4):195-201.[Crossref]
- Çakır Dolu İ, Bilgili N. [Determining the practise and knowledge of medicine usage in a group of elderly people in Ankara]. TAF Preventive Medicine Bulletin. 2010;9(1): 37-44.[Link]
- Özbek S, Kaya E, Tekin A, Doğan Ş. [Medication compliance in elderly]. Turkish Journal of Geriatrics. 2006;9(3):177-81.[Link]
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