Objective: To investigate the changes in dry eye parameters, tear meniscus height and epithelial thickness over a shortterm period (working week) in long-term computer users. Material and Methods: There were 46 eyes of 23 patients with dry eye symptoms who used computers for at least 6 h per day were included in this study. The Schirmer's test scores, tear break-up time (TBUT), ocular surface disease index (OSDI) score, epithelial thickness and tear meniscus levels by spectral domain-optical coherence tomography were recorded. All measurements of the patients were repeated on Monday morning before starting work (first visit) and on Friday of the same week after work (second visit) without medication. Results: The mean TBUT values were 12.41±2.68 s, 9.69±2.39 s, the Schirmer's test values were 20±5.47 mm, 11.89±3.62 mm (p<0.001); the tear meniscus levels were 158.65±41.18 μm, 118.15±31.99 μm (p<0.001); the OSDI scores were 12.13±4.89, 18±5.50 (p<0.001); and the central corneal epithelium thicknesses were 33.5±5.81 μm, 33.19±6.10 μm (p=0.703) upon the first and second visit, respectively. There was no significant difference in central corneal epithelial thickness (CET) between the two visits (p=0.703). Conclusion: While changes in the OSDI score, the TBUT, the Schirmer's test score and the tear meniscus levels were observed in long-term computer users in the short-term working week period, there was no short-term effect on central CET.
Keywords: Computer user; dry eye; meniscus; corneal epithelial thickness
Amaç: Bu çalışmanın amacı, uzun süreli bilgisayar kullanıcılarında kısa dönem (hafta içi dönem) kuru göz parametreleri, gözyaşı menisküsü yüksekliği ve epitel kalınlığındaki değişiklikleri araştırmak. Gereç ve Yöntemler: Günde en az 6 saat bilgisayar kullanan, kuru göz semptomları olan 23 hastanın 46 gözü çalışmaya dâhil edildi. Schirmer testi, gözyaşı kırılma zamanı (GKZ), oküler yüzey hastalığı indeksi (OYHİ) skoru, epitel kalınlığı ve gözyaşı menisküs seviyeleri spektral domain optik koherens tomografi ile kaydedildi. Hastaların tüm ölçümleri pazartesi günü işe başlamadan önce sabah (1. vizit) ve aynı hafta cuma günü iş çıkışı (2. vizit) ilaçsız tekrarlandı. Bulgular: GKZ değerleri 1 ve 2. vizitte sırasıyla ortalama 12,41±2,68 sn, 9,69±2,39 sn (p<0,001); Schirmer test değerleri 20±5,47 mm, 11,89±3,62 mm (p<0,001); gözyaşı menisküs seviyeleri 158,65±41,18 μm, 118,15±31,99 μm (p<0,001); OYHİ skorları 12,13±4,89, 18±5,50 (p<0,001); santral kornea epitel kalınlıkları 33,5±5,81 μm, 33,19±6,10 μm (p=0,703) idi. Santral kornea epitel kalınlığı açısından 2 vizit arasında anlamlı fark yoktu (p=0,703). Sonuç: Kısa süre hafta içi döneminde, uzun süreli bilgisayar kullanıcılarında OYHİ skoru, GKZ, schirmer ve gözyaşı menisküs düzeylerinde değişiklikler gözlenirken, merkezi kornea epitel kalınlığı üzerinde değişiklik yoktu.
Anahtar Kelimeler: Bilgisayar kullanıcısı; kuru göz; OSDİ; menisküs; kornea epitel kalınlığı
- Uchino M, Schaumberg DA, Dogru M, Uchino Y, Fukagawa K, Shimmura S, et al. Prevalence of dry eye disease among Japanese visual display terminal users. Ophthalmology. 2008;115(11):1982-8. [Crossref] [PubMed]
- Blehm C, Vishnu S, Khattak A, Mitra S, Yee RW. Computer vision syndrome: a review. Surv Ophthalmol. 2005;50(3):253-62. [Crossref] [PubMed]
- Bali J, Neeraj N, Bali R. Computer vision syndrome: A review. J Clin Ophthalmol Res. 2014;2(1):61-8. [Crossref]
- Bhargava R, Kumar P, Kaur A, Kumar M, Mish ra A. The diagnostic value and accuracy of conjunctival impression cytology, dry eye symptomatology, and routine tear function tests in computer users. J Lab Physicians. 2014;6(2):102-8. [Crossref] [PubMed] [PMC]
- Patel S, Henderson R, Bradley L, Galloway B, Hunter L. Effect of visual display unit use on blink rate and tear stability. Optom Vis Sci. 1991;68:888Y92. [Crossref] [PubMed]
- Portello JK, Rosenfield M, Chu CA. Blink rate, incomplete blinks and computer vision syndrome. Optom Vis Sci. 2013;90(5):482-7. [Crossref] [PubMed]
- Apostol S, Filip M, Dragne C, Filip A. Dry eye syndrome. Etiological and therapeutic aspects. Oftalmologia. 2003;59(4):28-31. [PubMed]
- Karakılıç AV, Çömez AT. Non-invasive assessment of dry eye patients: Correlation of tear osmolarity, tear meniscus height and non-invasive tear break-up time with other tests. Turkiye Klinikleri J Ophthalmol. 2021;30(1):8-16. [Crossref]
- Craig JP, Nelson JD, Azar DT, Belmonte C, Bron AJ, Chauhan SK, et al. TFOS DEWS II Report Executive Summary. Ocul Surf. 2017; 15(4):802-12. [Crossref] [PubMed]
- Unlü C, Güney E, Akçay BİS, Akçalı G, Erdoğan G, Bayramlar H. Comparison of ocular-surface disease index questionnaire, tearfilm break-up time, and Schirmer tests for the evaluation of the tearfilm in computer users with and without dry-eye symptomatology. Clin Ophthalmol. 2012;6:1303-6. [Crossref] [PubMed] [PMC]
- Wei A, Le Q, Hong J, Wang W, Wang F, Xu J. Assessment of lower tear meniscus. Optom Vis Sci. 2016;93(11):1420-5. [Crossref] [PubMed]
- Abou Shousha M, Wang J, Kontadakis G, Feuer W, Canto AP, Hoffmann R, et al. Corneal epithelial thickness profile in dry-eye disease. Eye (Lond). 2020;34(5):915-22. [Crossref] [PubMed] [PMC]
- Köksoy Vayısoğlu S, Öncü E, Dursun Ö, Dinç E. Investigation of dry eye symptoms in lecturers by ocular surface disease index. Turk J Ophthalmol. 2019;49(3):142-8. [Crossref] [PubMed] [PMC]
- Schiffman RM, Christianson MD, Jacobsen G, Hirsch JD, Reis BL. Reliability and validity of the Ocular Surface Disease Index. Arch Ophthalmol. 2000;118(5):615-21. [Crossref] [PubMed]
- Lee SM, Chung SJ, Park JS, Lew H. Changes in Tear Meniscus Height Following Lower Blepharoplasty as Measured by Optical Coherence Tomography. Korean J Ophthalmol. 2018;32(5):344-52. [Crossref] [PubMed] [PMC]
- Moon JH, Lee MY, Moon NJ. Association between video display terminal use and dry eye disease in school children. J Pediatr Ophthalmol Strabismus. 2014;51(2):87-92. [Crossref] [PubMed]
- Hirota M, Uozato H, Kawamorita T, Shibata Y, Yamamoto S. Effect of incomplete blinking on tear film stability. Optom Vis Sci. 2013;90(7): 650-7. [Crossref] [PubMed]
- Shantakumari N, Eldeeb R, Sreedharan J, Gopal K. Computer use and vision-related problems among university students in ajman, United arab emirate. Ann Med Health Sci Res. 2014;4(2):258-63. [Crossref] [PubMed] [PMC]
- Nichols KK, Nichols JJ, Mitchell GL. The lack of association between signs and symptoms in patients with dry eye disease. Cornea. 2004;23(8):762-70. [Crossref] [PubMed]
- Öztürk HE, Terzi Ö, Yücel ÖE. Hastane çalışanlarında kuru göz şikâyetlerinin sıklığı ve risk faktörleri. MN Oftalmoloji. 2020; 27(4):187. [Link]
- Cardona G, García C, Serés C, Vilaseca M, Gispets J. Blink rate, blink amplitude, and tear film integrity during dynamic visual display terminal tasks. Curr Eye Res. 2011;36(3):190-7. [Crossref] [PubMed]
- Yazici A, Sari ES, Sahin G, Kilic A, Cakmak H, Ayar O, et al. Change in tear film characteristics in visual display terminal users. Eur J Ophthalmol. 2015;25(2):85-9. [Crossref] [PubMed]
- Wu H, Wang Y, Dong N, Yang F, Lin Z, Shang X, et al. Meibomian gland dysfunction determines the severity of the dry eye conditions in visual display terminal workers. PLoS One. 2014;9(8):e105575. [Crossref] [PubMed] [PMC]
- Herrero-Vanrell R, Peral A. Taller Internacional sobre Ojo Seco (DEWS). Actualización de la enfermedad [International Dry Eye Workshop (DEWS). Update of the disease]. Arch Soc Esp Oftalmol. 2007;82(12):733-4. Spanish. [Crossref] [PubMed]
- Pflugfelder SC. Tear dysfunction and the cornea: LXVIII Edward Jackson Memorial Lecture. Am J Ophthalmol. 2011;152(6):900-9.e1. [Crossref] [PubMed] [PMC]
- Prakash G, Agarwal A, Mazhari AI, Chari M, Kumar DA, Kumar G, et al. Reliability and reproducibility of assessment of corneal epithelial thickness by fourier domain optical cohe rence tomography. Invest Ophthalmol Vis Sci. 2012;53(6):2580-5. [Crossref] [PubMed]
- Francoz M, Karamoko I, Baudouin C, Labbé A. Ocular surface epithelial thickness evaluation with spectral-domain optical coherence tomography. Invest Ophthalmol Vis Sci. 2011; 52(12):9116-23. [Crossref] [PubMed]
- Fabiani C, Barabino S, Rashid S, Dana MR. Corneal epithelial proliferation and thickness in a mouse model of dry eye. Exp Eye Res. 2009;89(2):166-71. [Crossref] [PubMed] [PMC]
- Liang Q, Liang H, Liu H, Pan Z, Baudouin C, Labbé A. Ocular Surface Epithelial Thickness Evaluation in Dry Eye Patients: Clinical Correlations. J Ophthalmol. 2016;2016:1628469. [Crossref] [PubMed] [PMC]
- Erdélyi B, Kraak R, Zhivov A, Guthoff R, Németh J. In vivo confocal laser scanning microscopy of the cornea in dry eye. Graefes Arch Clin Exp Ophthalmol. 2007;245(1):39-44. [Crossref] [PubMed]
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