Bağımlılıkta önemli yeri olan ve örtük bilişsel süreçler içinde yer alan bilişsel yanlılığı manipüle etmek amaçlı Bilişsel Yanlılık Modifikasyonu eğitim programı geliştirilmiştir. Bu eğitim programının temel hedefi, bağımlılık yapıcı maddeye karşı bilişsel yanlılık geliştirmiş olan hastaların bilişsel kalıplarını doğrudan değiştirerek aşerme ve nüksü önlemektir. Bilişsel yanlılığı değiştirebilmek için tasarlanan bu eğitim, dikkat yanlılığı veya yaklaşım yanlılığını manipüle etme yoluyla uygulanabilmektedir. Bu derleme makalesinde, Bilişsel Yanlılık Modifikasyonu eğitiminin aşerme ve nüks üzerindeki davranışsal ve nörolojik etkilerini inceleyen çalışmalar özetlenmiştir. İlgili literatüre göre alkol-madde Bilişsel Yanlılık Modifikasyonu eğitimi kişilerin aşerme seviyelerini azaltıcı özelliğe sahiptir. Ayrıca eğitim programı nüksü önleme ve/veya geciktirme üzerinde etkilidir. Nörobiyolojik açıdan eğitim programının istenmeyen davranışı kontrol etmeden sorumlu mediyal prefrontal bölgeyi aktive ettiği bulunmuştur. Bilişsel Yanlılık Modifikasyonu eğitim programı kavramsal olarak kanıtlanmıştır. Bundan sonraki konuyla ilgili yapılacak olan çalışmalar randomize kontrollü ve olası klinik etkiyi araştırma üzerine yapılmalıdır. Günümüzde, Bilişsel Yanlılık Modifikasyonu çalışmalarının küçük örneklem gruplarıyla çalışılması programın etkinliğinin genellenebilirliğini düşürmektedir. Bu nedenle, Bilişsel Yanlılık Modifikasyonu'nun her zamanki tedaviye ek olarak destekleyici tedavi şeklinde uygulanması için kontrollü ve büyük örnekleme sahip çalışmalara ihtiyaç vardır. Bağımlılık yapıcı maddenin düzenli olarak kullanımı maddeyle ilgili uyarana kişinin hassaslaşarak daha hızlı fark etmesine neden olur. Örtük olarak gerçekleşen bu bilişsel süreç bilişsel yanlılık olarak adlandırılır. Bilişsel yanlılık aşerme ve nüks riski ile pozitif ilişkilidir.
Anahtar Kelimeler: Bilişsel yanlılık modifikasyonu; dikkat yanlılığı; yaklaşım yanlılığı; bağımlılık; nüks
Cognitive Bias Modification (CBM) has been developed to manipulate cognitive bias that play an important role in addiction research and are part of the implicit cognitive process. The primary goal of this training program is to directly modify the cognitive patterns of patients who have developed cognitive bias towards addictive subtances in order to prevent craving and relapse. CBM can be implemented by manipulating attentional bias or approach bias to modify cognitive bias. This review summarizes studies that examine the behavioral and neurological effects of CBM on craving and relapse. According to the relevant literature, CBM training for alcohol and subtance addiction has been found to reduce craving level. Additionally, the program is effective in preventing or delaying relapse. Neurobiologically, CBM has been found to activate the medial prefrontal cortex region where is responsible for controlling and inhibiting behavior. Moreover, CBM training has been conceptually proven. Future studies on this topic should be conducted using randomized controlled trials to investigate the potentional clinical effects. Currently, CBM studies with small sample size limit the generalizability of the program effectiveness. Therefore, controlled studies with large sample size are needed to apply CBM as a supportive treatment in addiction to treament as usual. Regular use of addictive products facilities the recognition of the substance-related stimuli faster. This cognitive process is called as a cognitive bias. Cognitive bias is positively correlated with craving and relapse.
Keywords: Cognitive bias modification; attentional bias; apporach bias; addiction; relapse
- Uzbay İT. Madde Bağımlılığı. 1. Baskı. İstanbul: İstanbul Tıp Kitabevi; 2015.
- Stacy AW, Wiers RW. Implicit cognition and addiction: a tool for explaining paradoxical behavior. Annu Rev Clin Psychol. 2010;6:551-75. [Crossref] [PubMed] [PMC]
- Robinson TE, Berridge KC. The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Brain Res Rev. 1993;18(3):247-91. [Crossref] [PubMed]
- Macleod C. Cognitive bias modification procedures in the management of mental disorders. Curr Opin Psychiatry. 2012;25(2):114-20. [Crossref] [PubMed]
- Cox WM, Hogan LM, Kristian MR, Race JH. Alcohol attentional bias as a predictor of alcohol abusers' treatment outcome. Drug Alcohol Depend. 2002;68(3):237-43. [Crossref] [PubMed]
- Waters AJ, Shiffman S, Bradley BP, Mogg K. Attentional shifts to smoking cues in smokers. Addiction. 2003;98(10):1409-17. [Crossref] [PubMed]
- Marissen MA, Franken IH, Waters AJ, Blanken P, van den Brink W, Hendriks VM. Attentional bias predicts heroin relapse following treatment. Addiction. 2006;101(9):1306-12. [Crossref] [PubMed]
- Türkoğlu S, Amado S, Gönül AS, Eker MÇ. Comparison of alcohol attentional bias and craving among alcohol abusers and non-abusers. Psikiyatride Güncel Yaklaşımlar. 2022;14(Supp 1):75-82. [Crossref]
- Field M, Cox WM. Attentional bias in addictive behaviors: a review of its development, causes, and consequences. Drug Alcohol Depend. 2008;97(1-2):1-20. [Crossref] [PubMed]
- Klinger E. Emotional influences on cognitive processing, with implications for theories of both. In: Gollwitzer PM, Bargh JA, eds. The Psychology of Action: Linking Cognition and Motivation to Behavior. 1st ed. New York: The Guilford; 1996.
- MacLeod C, Mathews A, Tata P. Attentional bias in emotional disorders. J Abnorm Psychol. 1986;95(1):15-20. [Crossref] [PubMed]
- Stroop JR. Studies of interference in serial verbal reactions. Journal of Experimental Psychology. 1935;18(6):643-62. [Crossref]
- Raymond JE, Shapiro KL, Arnell KM. Temporary suppression of visual processing in an RSVP task: an attentional blink? . J Exp Psychol Hum Percept Perform. 1992;18(3):849-60. [Crossref] [PubMed]
- Rinck M, Becker ES. Approach and avoidance in fear of spiders. J Behav Ther Exp Psychiatry. 2007;38(2):105-20. [Crossref] [PubMed]
- Cox WM, Fadardi JS, Pothos EM. The addiction-stroop test: Theoretical considerations and procedural recommendations. Psychol Bull. 2006;132(3):443-76. [Crossref] [PubMed]
- Field M, Werthmann J, Franken I, Hofmann W, Hogarth L, Roefs A. The role of attentional bias in obesity and addiction. Health Psychol. 2016;35(8):767-80. [Crossref] [PubMed]
- Sanna A, Fattore L, Badas P, Corona G, Cocco V, Diana M. Intermittent Theta Burst Stimulation of the Prefrontal Cortex in Cocaine Use Disorder: A Pilot Study. Front Neurosci. 2019;13:765. [Crossref] [PubMed] [PMC]
- Mogg K, Bradley BP, Field M, De Houwer J. Eye movements to smoking-related pictures in smokers: relationship between attentional biases and implicit and explicit measures of stimulus valence. Addiction. 2003;98(6):825-36. [Crossref] [PubMed]
- Watson P, De Wit S, Cousijn J, Hommel B, Wiers RW. Motivational mechanisms underlying the approach bias to cigarettes. Journal of Experimental Psychopathology. 2013;4(3):250-62. [Crossref]
- Cox WM, Fadardi JS, Intriligator JM, Klinger E. Attentional bias modification for addictive behaviors: clinical implications. CNS Spectr. 2014;19(3):215-24. [Crossref] [PubMed]
- Wiers RW, Stacy AW. Implicit cognition and addiction. current directions in psychological science. 2006;15(6):292-96. [Crossref]
- Fadardi JS, Cox WM. Reversing the sequence: reducing alcohol consumption by overcoming alcohol attentional bias. Drug Alcohol Depend. 2009;101(3):137-45. [Crossref] [PubMed]
- Cabrera EA, Wiers CE, Lindgren E, Miller G, Volkow ND, Wang GJ. Neuroimaging the effectiveness of substance use disorder treatments. J Neuroimmune Pharmacol. 2016;11(3):408-33. [Crossref] [PubMed]
- Schoenmakers TM, de Bruin M, Lux IF, Goertz AG, Van Kerkhof DH, Wiers RW. Clinical effectiveness of attentional bias modification training in abstinent alcoholic patients. Drug Alcohol Depend. 2010;109(1-3):30-6. [Crossref] [PubMed]
- Boendermaker WJ, Prins PJ, Wiers RW. Cognitive Bias Modification for adolescents with substance use problems--Can serious games help? J Behav Ther Exp Psychiatry. 2015;49(Pt A):13-20. [Crossref] [PubMed]
- Ziaee SS, Fadardi JS, Cox WM, Yazdi SA. Effects of attention control training on drug abusers' attentional bias and treatment outcome. J Consult Clin Psychol. 2016;84(10):861-73. [Crossref] [PubMed]
- MacLeod C, Rutherford E, Campbell L, Ebsworthy G, Holker L. Selective attention and emotional vulnerability: assessing the causal basis of their association through the experimental manipulation of attentional bias. J Abnorm Psychol. 2002;111(1):107-23. [Crossref] [PubMed]
- Heeren A, Mogoașe C, Philippot P, McNally RJ. Attention bias modification for social anxiety: A systematic review and meta-analysis. Clin Psychol Rev. 2015;40:76-90. [Crossref] [PubMed]
- Linetzky M, Pergamin-Hight L, Pine DS, Bar-Haim Y. Quantitative evaluation of the clinical efficacy of attention bias modification treatment for anxiety disorders. Depress Anxiety. 2015;32(6):383-91. Erratum in: Depress Anxiety. 2018;35(1):111-112. [Crossref] [PubMed]
- Price RB, Wallace M, Kuckertz JM, Amir N, Graur S, Cummings L, et al. Pooled patient-level meta-analysis of children and adults completing a computer-based anxiety intervention targeting attentional bias. Clin Psychol Rev. 2016;50:37-49. [Crossref] [PubMed] [PMC]
- Clerkin EM, Magee JC, Wells TT, Beard C, Barnett NP. Randomized controlled trial of attention bias modification in a racially diverse, socially anxious, alcohol dependent sample. Behav Res Ther. 2016;87:58-69. [Crossref] [PubMed] [PMC]
- Wiers RW, Eberl C, Rinck M, Becker ES, Lindenmeyer J. Retraining automatic action tendencies changes alcoholic patients' approach bias for alcohol and improves treatment outcome. Psychol Sci. 2011;22(4):490-7. [Crossref] [PubMed]
- Eberl C, Wiers RW, Pawelczack S, Rinck M, Becker ES, Lindenmeyer J. Approach bias modification in alcohol dependence: do clinical effects replicate and for whom does it work best? Dev Cogn Neurosci. 2013;4:38-51. [Crossref] [PubMed] [PMC]
- Rinck M, Wiers RW, Becker ES, Lindenmeyer J. Relapse prevention in abstinent alcoholics by cognitive bias modification: Clinical effects of combining approach bias modification and attention bias modification. J Consult Clin Psychol. 2018;86(12):1005-16. [Crossref] [PubMed]
- Boffo M, Zerhouni O, Gronau QF, van Beek RJJ, Nikolaou K, Marsman M, et al. Cognitive bias modification for behavior change in alcohol and smoking addiction: bayesian meta-analysis of individual participant data. Neuropsychol Rev. 2019;29(1):52-78. [Crossref] [PubMed] [PMC]
- Bradley BP, Field M, Healy H, Mogg K. Do the affective properties of smoking-related cues influence attentional and approach biases in cigarette smokers? J Psychopharmacol. 2008;22(7):737-45. [Crossref] [PubMed]
- Palfai TP, Ostafin BD. Alcohol-related motivational tendencies in hazardous drinkers: assessing implicit response tendencies using the modified-IAT. Behav Res Ther. 2003;41(10):1149-62. [Crossref] [PubMed]
- Veenstra EM, de Jong PJ. Reduced automatic motivational orientation towards food in restricting anorexia nervosa. J Abnorm Psychol. 2011;120(3):708-18. [Crossref] [PubMed]
- Cousijn J, Goudriaan AE, Wiers RW. Reaching out towards cannabis: approach-bias in heavy cannabis users predicts changes in cannabis use. Addiction. 2011;106(9):1667-74. Erratum in: Addiction. 2011;106(11):2053. [Crossref] [PubMed] [PMC]
- Wiers RW, van Woerden N, Smulders FTY, de Jong PJ. Implicit and explicit alcohol-related cognitions in heavy and light drinkers. J Abnorm Psychol. 2002;111(4):648-58. [Crossref] [PubMed]
- Luijten M, Veltman DJ, van den Brink W, Hester R, Field M, Smits M, et al. Neurobiological substrate of smoking-related attentional bias. Neuroimage. 2011;54(3):2374-81. [Crossref] [PubMed]
- Vollstädt-Klein S, Loeber S, Richter A, Kirsch M, Bach P, von der Goltz C, et al. Validating incentive salience with functional magnetic resonance imaging: association between mesolimbic cue reactivity and attentional bias in alcohol-dependent patients. Addict Biol. 2012;17(4):807-16. [Crossref] [PubMed]
- Goldstein RZ, Volkow ND. Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications. Nat Rev Neurosci. 2011;12(11):652-69. [Crossref] [PubMed] [PMC]
- Ray RD, Zald DH. Anatomical insights into the interaction of emotion and cognition in the prefrontal cortex. Neurosci Biobehav Rev. 2012;36(1):479-501. [Crossref] [PubMed] [PMC]
- Wiers CE, Stelzel C, Gladwin TE, Park SQ, Pawelczack S, Gawron CK, et al. Effects of cognitive bias modification training on neural alcohol cue reactivity in alcohol dependence. Am J Psychiatry. 2015;172(4):335-43. [Crossref] [PubMed]
- Phan KL, Taylor SF, Welsh RC, Ho SH, Britton JC, Liberzon I. Neural correlates of individual ratings of emotional salience: a trial-related fMRI study. Neuroimage. 2004;21(2):768-80. [Crossref] [PubMed]
- Wiers CE, Kühn S, Javadi AH, Korucuoglu O, Wiers RW, Walter H, et al. Automatic approach bias towards smoking cues is present in smokers but not in ex-smokers. Psychopharmacology (Berl). 2013;229(1):187-97. [Crossref] [PubMed]
- Contreras-Rodríguez O, Albein-Urios N, Perales JC, Martínez-Gonzalez JM, Vilar-López R, Fernández-Serrano MJ, et al. Cocaine-specific neuroplasticity in the ventral striatum network is linked to delay discounting and drug relapse. Addiction. 2015;110(12):1953-62. [Crossref] [PubMed]
- Levy DJ, Glimcher PW. The root of all value: a neural common currency for choice. Curr Opin Neurobiol. 2012;22(6):1027-38. [Crossref] [PubMed] [PMC]
- Waters AJ, Shiffman S, Sayette MA, Paty JA, Gwaltney CJ, Balabanis MH. Attentional bias predicts outcome in smoking cessation. Health Psychol. 2003;22(4):378-87. [Crossref] [PubMed] [PMC]
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