Turkiye Klinikleri Journal of Ophthalmology

.: ORIGINAL RESEARCH
The Effect of Prematurity on Refraction and Keratometric Measurements: Observational Research
Prematüritenin Kırma Kusurları ve Keratometrik Ölçümler Üzerine Etkisi: Tanımlayıcı Araştırma
Eşay KIRAN YENİCEa , Caner KARAb
aDepartment of Ophthalmology, University of Health Sciences Etlik Zübeyde Hanım Maternity and Women's Health Training and Research Hospital, Ankara, Türkiye
bClinic of Ophthalmology, Ankara City Hospital, Ankara, Türkiye
Turkiye Klinikleri J Ophthalmol. 2023;32(4):253-9
doi: 10.5336/ophthal.2023-98714
Article Language: EN
Full Text
ABSTRACT
 Objective: To compare refraction and keratometry measurements between preterm and full-term infants and to evaluate the possible effect of postmenstrual age (PMA) and birth weight (BW) on these parameters. Material and Methods: Fifty eight preterm infants (Group I) and 57 term infants (Group II) were enrolled. Each subject underwent ophthalmic examination and the results were recorded. Results: The study included 115 infants with a mean birth week of 35.17±3.96 weeks and a BW of 2510.70±896.72 g. Examination was performed at a mean PMA of 42.17±4.21 weeks in Group I and 46.18±3.12 weeks in Group II. The keratometry values of the groups were 47.88±3.19 diopters (D) in Group I and 45.70±3.38 D in Group II, respectively. Corneal refractive power of preterm infants was found to be significantly higher than full-term infants (p=0.001). Inverse relationship was found between PMA and keratometry value in preterm infants (p<0.001, ß=-0.63), and between PMA and BW and keratometry values in term infants (p=0.03, ß=-0.28 for PMA, p=0.02, ß=-0.30 for BW). In addition, preterm infants were significantly more myopic than full-term infants (p=0.009). Conclusion: In conclusion, this study supports that myopic shift, as well as the steep and refractive corneas, are significantly associated with the prematurity.

Keywords: Retinopathy of prematurity; keratometry; refractive outcome; myopia; term birth
ÖZET
 Amaç: Bu çalışmanın amacı, preterm ve term yenidoğanların refraksiyon ve keratometri ölçümlerini karşılaştırmak ve postmenstrüel yaş (PMY) ve doğum ağırlığının (DA) bu parametreler üzerindeki olası etkisini değerlendirmektir. Gereç ve Yöntemler: Elli sekiz prematüre (Grup I) ve 57 term (Grup II) yenidoğan çalışmaya dâhil edildi. Tüm yenidoğanlara detaylı göz muayenesi yapılarak sonuçlar kaydedildi. Bulgular: Çalışmaya ortalama doğum haftası 35,17±3,96 hafta ve doğum ağırlığı 2510,70±896,72 g olan 115 yenidoğan dâhil edildi. Ortalama postmenstrüel muayene haftası Grup I'de 42,17±4,21 hafta, Grup II'de ise 46,18±3,12 hafta idi. Grupların keratometri değerleri sırasıyla Grup I'de 47,88±3,19 diyoptri (D) ve Grup II'de 45,70±3,38 D idi. Prematüre yenidoğanların korneal kırma gücü, term yenidoğanlardan anlamlı olarak yüksek bulundu (p=0,001). Prematüre yenidoğanlarda PMY ile keratometri değeri arasında (p<0,001, ß=-0,63), term yenidoğanlarda PMY ile DA ve keratometri değerleri arasında ters yönlü ilişki tespit edildi (PMY için p=0,03, ß=-0,28, p=0,02, DA için ß=-0,30). Ek olarak prematüre yenidoğanlar, term yenidoğanlara göre anlamlı olarak daha miyop idi (p=0.009). Sonuç: Sonuç olarak bu çalışma, dik ve kırıcı korneaların yanı sıra miyopik kırma kusurunun prematürite ile önemli ölçüde ilişkili olduğunu desteklemektedir.

Anahtar Kelimeler: Prematüre retinopatisi; keratometri; kırma kusuru; miyop; term doğum
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