Vasküler malformasyonlar, vaskülogenezis esnasında meydana gelen hatalar sonucu oluşmaktadır. Doğumda mevcuttur, ancak yaşamın ilerleyen zamanlarına kadar belirgin olmayabilmektedir. Bu malformasyonlar en sık baş ve boyunda bulunur, ancak vücudun herhangi bir yerinde ortaya çıkabilmektedir. Bu malformasyonlar sıklıkla deride görülür, ancak iç organları veya kemikleri nadiren etkilerler; yaklaşık %51 baş-boyunda meydana gelir ve erkek /kadın oranı 1/1,5'tir. Maksillofasiyal bölgedeki arteriyovenöz malformasyonları yönetmek karmaşıktır ve nüks oranı yüksektir. Arteriyovenöz malformasyonlar, karmaşık klinik görüntüleri olan ve vasküler malformasyonlar arasında hızlı akım gösterenler olarak bilinen konjenital lezyonlardır. Bu malformasyonlar, hızlı akım gösterdikleri için teşhis ve tedavisi önem arz etmektedir. Klinik görüntü değişkendir ve malformasyonun tipine olduğu kadar yerleşimine, boyutuna ve diğer yapılarla ilişkisine bağlıdır. Arteriyovenöz malformasyonların tanısı hem klinik sunuma hem de manyetik rezonans görüntülemeye özel önem verilerek bunu tamamlayan görüntüleme tekniklerine dayanmaktadır. Arteriyovenöz malformasyonların tedavisindeki güçlüklerden dolayı girişimsel radyolog, plastik cerrah, oftalmolojist, beyin cerrahı, diş hekiminden oluşan multidisipliner bie ekip yaklaşımını zorunlu kılar. Malformasyona ve klinik prezentasyona bağlı olarak tedavi seçenekleri; medikasyon, girişimsel teknikler veya cerrahi yolla olabilmektedir. Arteriyovenöz malformasyonları tedavi etmek için bildirilen yönetim teknikleri; embolizasyon, skleroterapi, lazer, cerrahi rezeksiyon ve güncel yaklaşımları içermektedir. Bu derlemenin amacı, arteriyovenöz malformasyon tedavisine ilişkin kapsamlı derleme ve güncel kavramları belirlemek, tanı ve tedavi yöntemleri hakkında bilgi sunmaktır.
Anahtar Kelimeler: Arteriyovenöz malformasyonlar; embolizasyon; kanama
Vascular malformations occur as a result of errors occurring during vasculogenesis. It is present at birth but may not become apparent until later in life. These malformations are most commonly found in the head and neck, but can occur anywhere in the body. They are often seen on the skin but rarely affect internal organs or bones; approximately 51% occur in the head and neck, with a male-to-female ratio of 1:1.5. Arteriovenous malformations (AVMs) are congenital lesions that have complex clinical images and are known to show rapid flow among vascular malformations. These malformations are frequently observed in the maxillofacial region. Managing AVMs in the maxillofacial region is complex, with a high recurrence rate. Since these malformations show rapid flow, their diagnosis and treatment are important. The clinical picture is variable and depends on the type of malformation as well as its location, size, and relationship with other structures. In this review, we aimed to present the diagnosis and treatment of AVMs with up-to-date information. The diagnosis of AVMs is based on both clinical presentation and imaging techniques that complement it, with special emphasis on magnetic resonance imaging. Due to the challenges in treating AVMs, it necessitates a multidisciplinary team approach involving interventional radiologists, plastic surgeons, ophthalmologists, neurosurgeons, and dentists. Treatment depending on the malformation and clinical presentation; It can be done through medication, interventional techniques or surgery. Reported management techniques for treating AVMs include embolization, sclerotherapy, laser therapy, surgical resection, and current approaches. The purpose of this review is to provide a comprehensive overview and update on the treatment of arteriovenous malformations, identifying current concepts, and discussing diagnostic and therapeutic methods.
Keywords: Arteriovenous malformations; embolization; haemorrhage
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