Turkiye Klinikleri Journal of Nursing Sciences

.: ORIGINAL RESEARCH
Kemoterapi Tedavisi Alan Çocuklarda Oral Mukozitin Yaşam Kalitesine Etkisi: Tanımlayıcı Araştırma
Effects of Oral Mucositis on the Quality of Life of Children Receiving Chemotherapy: Descriptive Study
Azime HACIOĞLU GÜVENa , Hatice BAL YILMAZb
aPamukkale Üniversitesi Sağlık Bilimleri Fakültesi, Çocuk Sağlığı ve Hastalıkları Hemşireliği ABD, Denizli, Türkiye
bEge Üniversitesi Hemşirelik Fakültesi, Çocuk Sağlığı ve Hastalıkları Hemşireliği ABD, İzmir, Türkiye
Turkiye Klinikleri J Nurs Sci. 2023;15(2):349-56
doi: 10.5336/nurses.2022-94621
Article Language: TR
Full Text
ÖZET
 Amaç: Bu araştırma, pediatrik hematoloji-onkoloji kliniklerinde kemoterapi tedavisi alan çocuklarda oral mukozitin (OM) yaşam kalitesine etkisini incelemek amacı ile gerçekleştirilmiştir. Gereç ve Yöntemler: Tanımlayıcı ve kesitsel tipteki bu araştırmanın örneklemini kemoterapi tedavisi alan 58 çocuk oluşturmuştur. Verilerin toplanmasında ''Çocuk ve Ebeveyn Bilgi Formu'', ''Dünya Sağlık Örgütü Mukozit Değerlendirme İndeksi'', ''Uluslararası Çocuk Mukozit Değerlendirme Ölçeği [Children's International Mucositis Evaluation Scale (ChIMES)]'' ve ''7-12 Yaş Pediatrik Onkoloji Hastaları Yaşam Kalitesi Ölçeği Çocuk Formu'' kullanılmıştır. Verilerin analizinde; tanımlayıcı istatistiksel yöntemler, Spearman korelasyon analizi, bağımsız örneklem t-testi ve ANOVA analizi kullanılmıştır. Bulgular: Kemoterapi tedavisi öncesi (0. gün) çocukların tamamının (%100) mukozit derecesi, 0 derece olarak tanımlanmıştır. Kemoterapi tedavisinden 10 gün sonra çocuklarda farklı derecelerde mukozit görülmüştür. Kemoterapi tedavisi alan çocuklarda gelişen OM ile yaşam kalitesi arasında istatistiksel olarak anlamlı bir fark olduğu bulunmuştur (p<0,01). Çocukların Dünya Sağlık Örgütü Mukozit Değerlendirme İndeksine göre mukozit derecesi arttıkça ChIMES'e göre ağrı puan ortalamalarının yükseldiği saptanmıştır. Çocukların mukozit derecesi ile ağrı puan ortalamaları (r=0,948**, p<0,01) ve yaşam kalitesi puan ortalamaları (r=0,614**, p<0,01) arasında pozitif yönde çok güçlü düzeyde ilişki bulunmuştur. Sonuç: Çocuklarda mukozit derecesinin artması ile ağrı puanlarının arttığı ve bunlara paralel olarak yaşam kalitesinin de azaldığı görülmüştür. Kemoterapi tedavisi alan çocuklarda yaşam kalitesinin artırılması için ağız içinin her gün değerlendirilmesi ve mukozit gelişme durumunun değerlendirilerek, çocuklarda mukozit gelişiminin mümkün olduğunca azaltılması ve mukozite bağlı ağrının azaltılmasına ilişkin önlemlerin erken dönemde alınması önerilir.

Anahtar Kelimeler: Mukozit; çocuk; kemoterapi; yaşam kalitesi; hemşirelik
ABSTRACT
 Objective: This study was conducted to investigate the effect of oral mucositis on the quality of life in children receiving chemotherapy treatment in pediatric hematology-oncology clinics. Material and Methods: The sample of this descriptive and cross-sectional study consisted of 58 children who had been receiving chemotherapy treatment. A ''Child and Parent Information Form,'' the ''World Health Organization Mucositis Classification Index,'' the ''Children's International Mucositis Evaluation Scale (ChIMES),'' and the ''Scale for Quality of Life in Pediatric Oncology Patients Aged 7-12 Child'' were used to collect study data. Descriptive statical methods, independent sample t-test, Spearman correlation analysis, ANOVA analysis were used to evaluate the data. Results: The grade of mucositis in all children (100%) before chemotherapy treatment (day 0) was defined as grade 0. Ten days after chemotherapy treatment, it was determined that the children had varying grades mucositis. It was found that there was a statistically significant difference between oral mucositis developing in children receiving chemotherapy and their quality of life (p<0.01). It was determined that as the grade of children's mucositis increased according to the World Health Organization Mucositis Assessment Index, their mean pain scores increased according to ChIMES, as well. A very strong positive correlation was found between the degree of mucositis and the mean scores of pain (r=0.948**, p<0.01) and mean scores of quality of life (r=0.614**, p<0.01) of the children. Conclusion: It was found that as the severity of mucositis in children increased, their pain scores increased, and their quality of life decreased in parallel to it. To increase the quality of life in children receiving chemotherapy, it is recommended to evaluate the oral cavity every day, reduce the development of mucositis as much as possible, and take measures to relieve the mucositis-induced pain in the early period.

Keywords: Mucositis; child; chemotherapy; quality of life; nursing
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-To send print publications/correspondences

-To send press releases or notifications through e-mail

-To generate a list for an event or competition

By using www.turkiyeklinikleri.com you are considered to agree that;

-Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. cannot be hold responsible for any user’s illegal and immoral behavior,

-Terms of use may change from time to time,

-It is not responsible for other websites’ contents it cannot control or the harms they may cause although it uses the connection they provided.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. may block the website to users in the following events:

-Information with wrong, incomplete, deceiving or immoral expressions is recorded to the website,

-Proclamation, advertisement, announcement, libelous expressions are used against natural person or legal identity,

-During various attacks to the website,

-Disruption of the website because of a virus.

Written, visual and audible materials of the website, including the code and the software are under protection by legal legislation.

Without the written consent of Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. the information on the website cannot be downloaded, changed, reproduced, copied, republished, posted or distributed.

All rights of the software and the design of the website belong to Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. will be pleased to hear your comments about our terms of use. Please share the subjects you think may enrich our website or if there is any problem regarding our website.

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