Turkiye Klinikleri Journal of Dental Sciences

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Bifosfanat Tedavisinin Hareketli Bölümlü Protez Kullanan Hastalar Üzerine Etkisi
Effect of Bisphosphonate Treatment on Patients Using Removable Partial Prosthesis
Meryem ŞAHİNa, Fatma ÜNALANa, Sırmahan ÇAKARERb
aProtetik Diş Tedavisi AD,
bAğız, Diş ve Çene Cerrahisi AD, İstanbul Üniversitesi Diş Hekimliği Fakültesi, İstanbul, TÜRKİYE
Turkiye Klinikleri J Dental Sci. 2019;25(2):220-5
doi: 10.5336/dentalsci.2018-62653
Article Language: TR
Full Text
ÖZET
 Bisfosfonatlar; osteoporoz, multipl miyelom, hiperkalsemi, Paget hastalığı, fibröz displazi gibi metabolik kemik hastalıklarının tedavisinde kemik rezorpsiyonunu önlemede oldukça etkilidir. Bununla birlikte, kemikte yeniden yapılanmayı baskılayarak bazı komplikasyonlara neden olmaktadır. Bifosfonatların çenelerde görülen en önemli yan etkisi ise osteonekroza sebep olmasıdır. Bifosfonat kullanımına bağlı olarak çenelerde osteonekroz gelişiminde birçok faktör rol oynayabilmektedir. Uyumu kötü olan protez kullanımı bu faktörler arasında yer almaktadır. Bu çalışmada, 62 yaşındaki erkek olgunun alt çenesinde hareketli protez kullanımı sonucu oluşan bifosfonata bağlı osteonekroz tedavisinin anlatılması amaçlanmıştır.

Anahtar Kelimeler: Bifosfonat; osteonekroz; hareketli parsiyel protez
ABSTRACT
 Bisphosphonates; is very effective in preventing bone resorption in the treatment of metabolic bone diseases such as osteoporosis, multiple myeloma, hypercalcemia, Paget's disease, fibrous dysplasia. However, it causes some complications by suppressing restructuring in the bones. The most important side effect of bisphosphonates in dentistry is osteonecrosis of the jaw. Depending on the use of bisphosphonates, many factors can play a role in the development of osteonecrosis in the jaws and poor fitting prosthesis can be shown among these factors. In this case report, management of bisphosphonate related osteonecrosis in a 62 year old male patient who has removable partial denture prosthesis was described.

Keywords: Bisphosphonates; osteonecrosis; removable partial prosthesis
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