Journal of Traditional Medical Complementary Therapies

.: REVIEW
Antimikrobiyal Olarak Kullanılan Bazı Uçucu Yağların Antiviral Özellikleri ve Aromaterapi Uygulamaları
Antiviral Properties of Some Essential Oils Used as Antimicrobial Agents and Aromatherapy Applications
Aslı YAZICIOĞLUa, Hatice Betül BİNGÖLa
aPlatform Essencia, İstanbul, TÜRKİYE
J Tradit Complem Med. 2021;4(1):98-108
doi: 10.5336/jtracom.2020-75721
Article Language: TR
Full Text
ÖZET
 Uçucu yağlar (esansiyel yağlar da denir); aromatik bitkilerin çiçek, yaprak, kök, tohum, kabuk, reçine, odun, ot veya yumru gibi farklı organlarında oluşan ve sekonder metabolitler olarak adlandırılan bileşenlerin, distilasyon (damıtma) veya mekanik presleme (narenciye türleri) yöntemlerine maruz kalarak son ürün hâline getirilmesi ile elde edilirler. Uçucu yağlar başta terpenler (monoterpen, seskiterpen ve nadiren diterpenler), onların oksijenli türevleri ve fenilpropanoitler ve bazen de yağ asitleri olmak üzere çok sayıda bileşenden oluşurlar. Pek çok uçucu yağ ve bu yağlarda bulunan bileşenler, in vitro/in vivo çalışmalar ve klinik araştırmalar ile teyit edilmiş biyoaktiviteye sahip olup; analjezik, antiinflamatuar, antibakteriyel, antifungal, antiviral ve antioksidan etkileri ile bilinirler. Uçucu yağlardan ilaç, kozmetik, veterinerlik, gıda ve tarım gibi pek çok alanda faydalanılmaktadır. Uçucu yağların iyi ve sağlıklı olma hâlini destekleyici, koruyucu ve tedavi amaçlı sistemli ve kontrollü kullanımları aromaterapi olarak adlandırılmaktadır. Söz konusu yağlar asıl olarak solunum yolu ve cilt üzerinden kullanılmakta olup, dâhilen de uygulanabilmektedir. Uçucu yağlardan hazırlanan kapsül, supozituvar, ovül gibi ürünlerin sistemik uygulamalarıyla öne çıkan medikal aromaterapi, fitoterapinin özel bir alanı olarak değerlendirilebilir. Bu derlemede, Türkiye'de yetişen veya yaygın olarak kullanılan aromatik bitkilerden elde edilen uçucu yağların başta HSV-1, HSV-2, influenza, şiddetli akut solunum sendromu ve Orta Doğu solunum sendromu olmak üzere insanlarda enfeksiyona sebep olan virüslere karşı antiviral aktivitelerinin araştırıldığı çalışmalar sunulmuştur. Ayrıca uçucu yağların antiviral etki mekanizması değerlendirilmiş olup, potansiyel uygulamalar üzerine görüş bildirilmiştir.

Anahtar Kelimeler: Uçucu yağlar; terpenler; aromaterapi; tıbbi bitkiler; antiviral ajanlar
ABSTRACT
 Essential oils are obtained as final products through exposure to distillation or mechanical pressing (types of citrus) of components called secondary metabolites which are synthesized in different parts of aromatic plants, such as flowers, leaves, roots, seeds, bark, resin, wood, grass, or rhizomes. Essential oils consist of many components, primarily terpenes (monoterpen, sesquiterpene and rarely diterpenes), their oxygenated derivatives, phenylpropanoids and some fatty acids. Many essential oils and components found in these oils have bioactivity confirmed by in vitro/in vivo studies and clinical research and are known for their analgesic, anti-inflammatory, antibacterial, antifungal, antiviral and antioxidant effects. Essential oils are used in many fields such as veterinary medicine, agriculture, food, cosmetics and medicine. Therapeutic use of essential oils that support the well-being and health is named as aromatherapy, and can be applied internally as well as through the respiratory tract and skin. On the other hand, medical aromatherapy, which stands out with the systemic applications of products such as capsules, suppositories, ovules prepared from essential oils, can be considered as a special area of phytotherapy. This review is focused on the antiviral activity of essential oils derived from the medicinal and aromatic plants grown or commonly used in Turkey against viruses that cause infections in humans including HSV-1, HSV-2, influenza virus, severe acute respiratory syndrome and middle east respiratory syndrome. In addition, the antiviral mechanism of essential oils has been evaluated and opinions have been stated on potential applications.

Keywords: Essential oils; terpenes; aromatherapy; aromatic and medicinal plants; antiviral agents
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"Turkiye Klinikleri" is not responsible for executing late or never of this hereby "Terms of Use", privacy policy and "USER Contract" in any situation legally taken into account as force majeure. Being late or failure of performance or non-defaulting of this and similar cases like this will not be the case from the viewpoint of "Turkiye Klinikleri", and "Turkiye Klinikleri" will not have any damage liability for these situations. "Force majeure" term will be regarded as outside of the concerned party's reasonable control and any situation that "Turkiye Klinikleri" cannot prevent even though it shows due diligence. Also, force majeure situations include but not limited to natural disasters, rebellion, war, strike, communication problems, infrastructure and internet failure, power cut and bad weather conditions.

8. LAW AND AUTHORISATION TO FOLLOW

Turkish Law will be applied in practicing, interpreting the hereby "Terms of Use" and managing the emerging legal relationships within this "Terms of Use" in case of finding element of foreignness, except for the rules of Turkish conflict of laws. Ankara Courts and Enforcement Offices are entitled in any controversy happened or may happen due to hereby contract.

9. CLOSING AND AGREEMENT

Hereby "Terms of Use" come into force when announced in the "SITE" by "Turkiye Klinikleri". The users are regarded to agree to hereby contract terms by using the "SITE". "Turkiye Klinikleri" may change the contract terms and the changes will be come into force by specifying the version number and the date of change on time it is published in the "SITE".

 

30.03.2014

Privacy Policy

We recommend you to read the terms of use below before you visit our website. In case you agree these terms, following our rules will be to your favor. Please read our Terms of Use thoroughly.

www.turkiyeklinikleri.com website belongs to Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. and is designed in order to inform physicians in the field of health

www.turkiyeklinikleri.com cannot reach to user’s identity, address, service providers or other information. The users may send this information to the website through forms if they would like to. However, www.turkiyeklinikleri.com may collect your hardware and software information. The information consists of your IP address, browser type, operating system, domain name, access time, and related websites. www.turkiyeklinikleri.com cannot sell the provided user information (your name, e-mail address, home and work address, phone number) to the third parties, publish it publicly, or keep it in the website. Gathered information has a directing feature to be a source for the website’s visitor profile, reporting and promotion of the services.

www.turkiyeklinikleri.com uses the taken information:

-To enhance, improve and maintain the quality of the website

-To generate visitor’s profile and statistical data

-To determine the tendency of the visitors on using our website

-To send print publications/correspondences

-To send press releases or notifications through e-mail

-To generate a list for an event or competition

By using www.turkiyeklinikleri.com you are considered to agree that;

-Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. cannot be hold responsible for any user’s illegal and immoral behavior,

-Terms of use may change from time to time,

-It is not responsible for other websites’ contents it cannot control or the harms they may cause although it uses the connection they provided.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. may block the website to users in the following events:

-Information with wrong, incomplete, deceiving or immoral expressions is recorded to the website,

-Proclamation, advertisement, announcement, libelous expressions are used against natural person or legal identity,

-During various attacks to the website,

-Disruption of the website because of a virus.

Written, visual and audible materials of the website, including the code and the software are under protection by legal legislation.

Without the written consent of Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. the information on the website cannot be downloaded, changed, reproduced, copied, republished, posted or distributed.

All rights of the software and the design of the website belong to Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. will be pleased to hear your comments about our terms of use. Please share the subjects you think may enrich our website or if there is any problem regarding our website.

info@turkiyeklinikleri.com