Turkiye Klinikleri Journal of Ophthalmology

.: ORIGINAL RESEARCH
Ambliyopi Olgularında Koroidal Vasküler İndeks
Choroidal Vascular Index in Amblyopia Cases
Bilge ERAYDIN a , Can GEDİK a , Nurullah KOÇAK b , Leyla NİYAZ ŞAHİNb
aErbaa Devlet Hastanesi, Göz Hastalıkları Kliniği, Tokat, TÜRKİYE
bOndokuz Mayıs Üniversitesi Tıp Fakültesi, Göz Hastalıkları ABD, Samsun, TÜRKİYE
Turkiye Klinikleri J Ophthalmol. 2020;29(4):288-93
doi: 10.5336/ophthal.2020-73662
Article Language: TR
Full Text
ÖZET
 Amaç: Bu çalışmada, ambliyopik gözlerde koroidal vasküler indeks (KVİ) ile koroidin vasküler yapısını değerlendirmek amaçlanmıştır. Gereç ve Yöntemler: Ambliyopi tanısı ile takipli 59 hasta ve benzer yaş grubunda 30 sağlıklı birey çalışmaya dâhil edildi. Hastaların refraktif değerleri, en iyi düzeltilmiş görme keskinlikleri (EİDGK), ambliyopi nedenleri, subfoveal koroidal kalınlıkları (SFKK), KVİ değerleri ve bu parametreler arasındaki ilişki incelendi. Hastaların gelişmiş derinlikli spektral domain optik koherens tomografi görüntüleri üzerinde, ImageJ yazılımı kullanıldı. Bu yazılım ile toplam koroidal alan (TKA), luminal alan (LA) ve stromal alan (SA) olarak ikiye ayrılıp LA'nın TKA'ya oranı KVİ olarak tanımlandı. Bulgular: Çalışma 24 anizometropik ambliyop hastanın 24 gözü, 35 strabismik ambliyop hastanın 35 gözü ve 30 sağlıklı bireyin 30 gözü olmak üzere, 89 göz üzerinde gerçekleştirildi. SFKK ortalaması strabismik ambliyopi grubunda 378,46±55,66 µm iken anizometropik ambliyopi grubunda 343,35±66,27 µm olarak değerlendirildi. Mevcut değerler kontrol grubuyla karşılaştırıldığında, strabismik ambliyopi grubunda saptanan artmış SFKK istatistiksel olarak anlamlı bulundu (p0,05). KVİ kontrol grubunda %63,27±1,08; strabismik ambliyopi grubunda %63,78±1,75; anizometropik ambliyopi grubunda %63,61±1,53 olarak saptandı. Strabismik ambliyopide KVİ artışı, kontrol grubuna oranla istatistiksel olarak anlamlıyken (p=0,046); anizometropik ambliyopide saptanan KVİ'nin kontrol ve strabismik ambliyopi grubu ile karşılaştırılmasında fark istatistiksel olarak anlamlı değildi (p>0,05). Sonuç: SFKK ve KVİ değerleri strabismik ambliyop olan gözlerde, anizometropik ambliyop ve sağlıklı gözlere oranla artmış olarak bulundu. (p<0,001). Anizometropik ambliyopinin kontrol grubu ve strabismik ambliyopi grubu ile karşılaştırılmasında SFKK için istatistiksel anlamlı fark saptanmadı (p>0,05). KVİ kontrol grubunda %63,27±1,08; strabismik ambliyopi grubunda %63,78±1,75; anizometropik ambliyopi grubunda %63,61±1,53 olarak saptandı. Strabismik ambliyopide KVİ artışı, kontrol grubuna oranla istatistiksel olarak anlamlıyken (p=0,046); anizometropik ambliyopide saptanan KVİ'nin kontrol ve strabismik ambliyopi grubu ile karşılaştırılmasında fark istatistiksel olarak anlamlı değildi (p>0,05). Sonuç: SFKK ve KVİ değerleri strabismik ambliyop olan gözlerde, anizometropik ambliyop ve sağlıklı gözlere oranla artmış olarak bulundu.

Anahtar Kelimeler: Ambliyopi; subfoveal koroidal kalınlık; koroidal vasküler indeks
ABSTRACT
 ABS TRACT Objective: To evaluate the vascular structure of the choroid with choroidal vascular index (CVI) in amblyopic eyes. Material and Methods: Fifty nine patients followed up with the diagnosis of amblyopia diagnosis and 30 healthy individuals of the similar age were included in the study. Refractive values, best corrected visual acuity (BCVA), causes of amblyopia, subfoveal choroidal thickness (SFCT), CVI values and relationship between these parameters were analyzed. ImageJ software was used on enhanced depth spectral domain optical coherence tomography (EDI-OCT) images of the patients. With this software, the total choroidal area (TCA) was divided into luminal area (LA) and stromal area (SA). The ratio of LA to TCA was defined as CVI. Results: The study was performed on 89 eyes, including 24 eyes of 24 anisometropic amblyopia patients, 35 eyes of 35 strabismic amblyopia patients, and 30 eyes of 30 healthy individuals. The mean SFCT was 378.46±55.66 µm in the strabismic amblyopia group and 343.35±66.27 µm in the anisometropic amblyopia group. When the current values were compared with the control group, the increased SFCT in the strabismic amblyopia group was found to be statistically significant (p0.05). CVI was found as 63.27±1.08% in the control group, 63.78±1.75% in the strabismic amblyopia group, and 63.61±1.53% in the anisometropic amblyopia group. While the increase in CVI in strabismic amblyopia was statistically significant compared to the control group (p=0.046), the difference was not statistically significant in comparison of anisometropic amblyopia CVI values with the control and strabismic amblyopia group findings (p>0.05). Conclusion: SFCT and CVI values were found to be increased in eyes with strabismic amblyopia compared to anisometropic amblyopia and healthy eyes.

Keywords: Amblyopia; subfoveal choroidal thickness; choroidal vascular index
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