Journal of Reconstructive Urology

.: ORIGINAL RESEARCH
The Likelihood for Monosymptomatic Primary Nocturnal Enuresis May Be Greater in Children with Lower Pubic Symphysis Width
İdrar Kaçırma Şikâyeti ile Başvuran Hastaların Değerlendirilmesinde Yeni Bir Yöntem; Simfizis Pubis Eklem Genişliğinin Ölçümü
Uğur Ufuk IŞINa , Emin ÇAKMAKCIb , Nuray Gülden TANGALb , Numan İlteriş ÇEVİKc
aUniversity of Health Sciences Ankara Atatürk Sanatoryum Training and Research Hospital, Department of Pediatrics, Ankara, Türkiye
bUniversity of Health Sciences Ankara Atatürk Sanatoryum Training and Research Hospital, Department of Radiology, Ankara, Türkiye
cUniversity of Health Sciences Ankara Bilkent City Hospital, Department of Radiology, Ankara, Türkiye
J Reconstr Urol.
doi: 10.5336/urology.2024-104514
Article Language: EN
Full Text
ABSTRACT
Objective: The aim of this study was to investigate whether pubic symphysis width (PSW) and renal pelvis diameter (RPD) are associated with the presence of monosymptomatic primary nocturnal enuresis (MPNE) in children. Material and Methods: A total of 80 children, including 40 with MPNE and 40 without (controls) were included in this prospective original article conducted between May 2024 and June 2024. Age, sex, height, weight and body mass index were obtained. PSW and RPD were measured using an ultrasound device. To assess the associations between the measurements and MPNE, patients with and without MPNE were compared via various analyses. Results: The median age of the MPNE group was 8, and that of the control group was 9 years (p=0.039). In the MPNE group 55.0% were boys, while only 32.5% of the control group were boys (p=0.071). PSW, left RPD and average RPD were significantly lower in the MPNE group. Diagnostic analysis showed that a PSW value of <8 mm had 76.3% overall accuracy to distinguish children with MPNE from controls (80% sensitivity, 72.5% specificity, 74.4% positive predictive value and 78.4% negative predictive value). Multiple logistic regression showed that children with decreased PSW (<8 mm) had 8.527-fold higher likelihood of enuresis, after adjusting for age, sex, BMI and presence of spina bifida (p<0.001). Conclusion: Lower PSW (<8 mm) was found to be an independent risk factor and a significant predictor for MPNE, after matching for age, sex, BMI and spina bifida presence. RPD was not associated with enuresis or PSW-apart from a minor correlation.

Keywords: Monosymptomatic primary nocturnal enuresis; pubic symphysis width; diameter of the renal pelvis; ultrasound
ÖZET
Amaç: Radyolojik değerlendirme, özellikle de ultrasonografi (USG), monosemptomatik primer nokturnal enürezis (MPNE) araştırmalarında sıklıkla kullanılmaktadır. Sonuçlar alt üriner sistem USG incelemesinin yararı konusunda çelişkilidir ve ayrıca renal USG çalışmaları kesin olmayan bulgular bildirmiştir. Bu çalışmanın amacı, pubik simfizis genişliği (PSG) ve renal pelvis çapının (RPÇ) çocuklarda MPNE varlığı ile ilişkili olup olmadığını araştırmaktır. Gereç ve Yöntemler: Mayıs 2024-Haziran 2024 tarihleri arasında yürütülen bu prospektif vaka-kontrol çalışmasına 40'ı MPNE olan ve 40'ı kontrol grubu olmak üzere toplam 80 çocuk dâhil edilmiştir. Yaş, cinsiyet, boy, kilo ve beden kitle indeksi (BKİ) elde edilmiştir. PSG ve RPÇ, USG cihazı kullanılarak ölçülmüştür. Ölçümler ile MPNE arasındaki ilişkileri değerlendirmek için MPNE olan ve olmayan hastalar tek değişkenli ve çok değişkenli analizlerle karşılaştırılmıştır. Bulgular: MPNE grubunun ortanca yaşı 8 (7-10), kontrol grubununki ise 9 (7,5-11) idi (p=0,039). MPNE grubunun %55,0'i erkek iken kontrol grubunun yalnızca %32,5'i erkekti (p=0,071). PSG, sol RPÇ ve ortalama RPÇ, MPNE grubunda anlamlı derecede düşüktü. Tanısal analiz, PSG değerinin <8 mm olmasının MPNE'li çocukları kontrol grubundan ayırt etmede %76,3 genel doğruluğa sahip olduğunu göstermiştir (%80 duyarlılık, %72,5 özgüllük, %74,4 pozitif prediktif değer ve %78,4 negatif prediktif değer). Çoklu lojistik regresyon, yaş, cinsiyet, BKİ ve spina bifida varlığı ayarlandıktan sonra, PSG'si azalmış (<8 mm) çocukların enürezis olasılığının 8,527 kat daha yüksek olduğunu göstermiştir (p<0,001). Sonuç: Düşük PSG (<8 mm), yaş, cinsiyet, BKİ ve spina bifida varlığı için eşleştirme yapıldıktan sonra bağımsız bir risk faktörü ve MPNE için anlamlı bir belirleyici olarak bulunmuştur. RPÇ, küçük bir korelasyon dışında enürezis veya PSG ile ilişkili saptanmamıştır.

Anahtar Kelimeler: Monosemptomatik primer nokturnal enürezis; simfizis pubis genişliği; renal pelvis çapı; ultrasonografi

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