Amaç: Yoğun bakım ünitemizde yatan intoksikasyon vakalarının demografik özellikler, neden ve prognoz açısından retrospektif olarak incelenmesidir. Gereç ve Yöntemler: Yoğun bakım ünitesine 2006-2015 yılları arasında intoksikasyon nedeni ile yatan 333 hastanın verileri retrospektif olarak incelendi. Hastaların yaş, cinsiyet, intoksikasyon etkeni, yoğun bakım ünitesine kabul zamanı, kardiyak ve solunumsal destekleri ve mortalite oranları kaydedildi. Bulgular: Hastaların mediyan yaş değeri (min 12, max 88) idi. Hastaların %31,2 (n=104)'ü erkek, %68,8 (n=229)'i kadındı. İntoksikasyon etkenlerinin dağılımına bakıldığında; %86,7!sinin ilaçlar, %4'ünün alkol, %1,9'unun karbonmonoksit, %2,4'ünün besin, %0,9'unun pestisit-organofosfat, %1,4?ünün uyuşturucu madde, %0,7'sinin böcek ısırması ve %0,2'sinin koroziv madde olduğu görüldü. İntoksikasyon vakalarının %91,6 (n=305)'i intihar olgusuydu. İntihar vakalarının %17,1 (n=57)'inin psikiyatrik tedavi aldığı görüldü. Üç yüz on altı hastaya (%94,8) tıbbi destek tedavi, 14 (%4,2)'üne mekanik ventilasyon, 5 (%1,5)'ine hemodiyaliz, 13 (%3,9)'üne kardiyak inotropik ilaç infüzyonu uygulandı. Dokuz yıl süre ile (2006-2015) intoksikasyon tanısıyla yatan hastaların %93,4 (n=311)'ünün şifa ile taburcu olduğu, %1,5 (n=5)'inin ise eksitus olduğu saptandı. Sonuç: Çalışmamızda, genç ve kadın hastaların akut intoksikasyon açısından yüksek risk grubunu oluşturduğu gözlendi. Ayrıca, intihar girişimlerimde en sık olarak ilaçların kullanıldığı saptandı.
Anahtar Kelimeler: Yoğun bakım ünitesi; zehirlenme; intihar
Objective: We aimed to define the demographic characteristics, cause and prognosis of intoxicated patients in intensive care unit retrospectively. Material and Methods: 333 intoxicated patients who were admitted to our intensive care unit between 2006-2015 were analyzed retrospectively. The patients were evaluated for age, gender, drug or substance that causes intoxication, time of aplication to intensive care unit, cardiovascular support and respiratory support, and mortality rates. Results: The median age of patients was 24 (min 12, max 88). 104 (31.2%) of the patients were male, 229 (68.8%) of the cases were female. The distribution of causes of intoxication were drugs 86.7%, alcohol 4%, carbonmonoxide 1,9%, food 2.4%, pesticidesorganophosphates 0.9%, illegal narcotic drugs 1.4%, insect bite 0.7 % and corrosive substance ingestion 0.2%. 305 (91.6%) were suicides. 57 (17.1%) patients were under psychiatric treatment. Medical treatment were administered to 316 (94.8%) patients, 14 (4.2%) patients required mechanical ventilation, 5 (1.5%) patients required hemodialysis, 13 (3.9%) patients required cardiovascular support. 311 (93.4%) of the patients were discharged from the intensive care unit, 5 (1.5%) of the patients died. Conclusion: We found that young and female patients consisted the high risk group for acute intoxication. Also medical pills were found the most cause of the suicide attempts.
Keywords: Intensive care units; poisoning; suicide
- Meredith TJ. Epidemiology of poisoning. Pharmacol Ther. 1993;59(3):251-6. [Crossref]
- Lee HL, Lin HJ, Yeh ST, Chi CH, Guo HR. Presentations of patients of poisoning and predictors of poisoning-related fatality: findings from a hospital-based prospective study. BMC Public Health. 2008;8(8):7. [Crossref][PubMed][PMC]
- Hanssens Y, Deleu D, Taqi A. Etiologic and demographic characteristics of poisoning: a prospective hospital-based study in Oman. J Toxicol Clin Toxicol. 2001;39(4):371-80. [Crossref][PubMed]
- Burillo-Putze G, Munne P, Dueñas A, Pinillos MA, Naveiro JM, Cobo J, et al; Clinical Toxicology Working Group, Spanish Society of Emergency Medicine (SEMESTOX). National multicentre study of acute intoxicationin emer gency departments of Spain. Eur J Emerg Med. 2003;10(2):101-4. [Crossref] [PubMed]
- Ab Rahman AF. Drug and chemical poisoning admissions at a teaching hospital in Malaysia. Hum Exp Toxicol. 2002;21(7):377-81. [Crossref][PubMed]
- Fernando R. The National Poisons Information Centre in Sri Lanka: the first ten years. J Toxicol Clin Toxicol. 2002;40(5):551-5. [Crossref] [PubMed]
- Ozköse Z, Ayoglu F. Etiological and demographical characteristics of acute adult poisoning in Ankara, Turkey. Hum ExpToxicol. 1999;18(10): 614-8. [Crossref] [PubMed]
- Litovitz TL, Klein-Schwartz W, Dyer KS, Shannon M, Lee S, Powers M. 1997 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med. 1998;16(5):443-97. [Crossref]
- Kavalci G, Ethemoglu FB, Batuman A, Kumral D, Emre C, Surgit M, et al. Epidemiological and cost analysis of self-poisoning cases in Ankara, Turkey. Iran Red Crescent Med J. 2014;16(11): e10856. [Crossref]
- Ersoy A, Kara D, Cangir CH, Erdoğan E, Ali A, Büyükyıldırım A. [Evaluating intoxicated patients in intensive care unit]. Okmeydanı Tıp Dergisi. 2013;29(2):72-5. [Crossref]
- Kaygusuz K, Gürsoy S, Kılıçcıoğlu F, Özdemirkol İ, Mimaroğlu C. [The retrospective analysis of the cases that were observed with the diagnosis of acute drug intoxication in the in tensive care unit of Cumhuriyet University Medical Faculty Hospital between 1998-2004 years]. CÜ Tıp Fakültesi Dergisi. 2004;26:161-5.
- Özayar E, Değerli S, Güleç H, Şahin Ş, Dereli N. [Retrospective analysis of intoxication cases in the ICU]. Yoğun Bakım Derg. 2011; 2(3):59-62. [Crossref]
- Yağan Ö, Akan B, Erdem D, Albayrak D, Bilal B, Göğüş N. [The retrospective analysis of the acute poisoning cases applying to the emergency unit in one year]. SETB. 2009;43(2):604.
- Dağlı R, Kocaoğlu N, Bayır H, Hakkı M, Erbesler ZA, Kahraman M, et al. [Investigation of intoxication cases in our intensive care unit]. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi. 2016;3(1):17-20.
- Duran M, Uludag Ö, Yuzkat N. Analysis of adul tintoxication cases treated in ICU: a sample from Adıyaman Region of Turkey. Medical Science and Discovery. 2016;3(2):71-5.
- Yalçın Ş, Aydoğan H, Büyükfırat E, Çiçek A, Karahan MA. [Evaluating the acute intoxication cases followed in intensive care unit in Sanlıurfa]. Journal of Harran University Med Faculty. 2010;7(3):77-80.
- Destegül D, Çapar A. [Evaluation of acute intoxication cases followed in Kayseri training and research hospital anesthesiology intensive care unit]. Turkiye Klinikleri J Anest Reanim. 2018;16(1):8-13. [Crossref]
- Karabulut N, Çelik Z, Atalay C. [A retrospective analysis of intoxication cases at Artvin state hospital. Eurasian J Med. 2007;39:198201.
- Harmancı P. [Sociodemographic characteristics of suicide cases in the world and Turkey]. Hacettepe University Faculty of Health Sciences Journal. 2015;1(1).
- Altay N, Atlas A. [The retrospective analysis of acute intoxication cases in the intensive care unit]. Journal of Harran University Medical Faculty. 2013;10(1):1-5.
- Koylu R, Dundar ZD, Koylu O, Akinci E, Akilli NB, Gonen MO, et al. The experiences in a toxicology unit: a review of 623 cases. J Clin Med Res. 2014;6(1):59-65. [Crossref][PubMed] [PMC]
- Aydın G, Atasever M, Gencay I, Çolak S, Büyükkoçak Ü. [A restrospective analysis of intoxication cases in the intensive care unit]. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi. 2018;(20): 274-9. [Crossref]
- Katı İ, Silay E, Tekin M, Tomak Y, Dilek İ. [Investigation of poisoning in adults in our reanimation unit]. Van Tıp Dergisi. 2004;11(3):81-4.
- Akkose S, Fedakar R, Bulut M, Çebicci H. [Epidemiolgy of poisoning in adults: a 5 yearstudy]. Acil Tıp Dergisi. 2003;3:8-10.
- Muhammedoğlu N, Başaranoğlu G, Gül YG, Toptaş M, Baltalı S, Özütürk B. [Evaluation of suicide and intoxication cases admitted to our newly opened intensive care unit]. Med Bull Haseki. 2014;52(3):153-7. [Crossref]
- Toptaş M, Akkoç İ, Kaya R, Uzman S, Gül YG, Yılmaz Y, et al. [Profile of patients with acute poisoning and factors effecting prognosis: a retrospective analysis in the intensive care]. Med Bull Haseki. 2014;52(1):29-33. [Crossref]
- Kaya S, Kararmaz A, Karaman H, Turhanoğlu S. [The retrospective analysis of the poisoning cases in intensive care unit]. Dicle Tıp Dergisi. 2006;33:242-4.
.: İşlem Listesi