Yenidoğanlarda oral lezyonlar nadir olarak görülse de diş hekimlerini, pediatristleri ve dermatologları yakından ilgilendirmektedir. Bu oral lezyonların sınıflandırılması için çalışmalar yapılmış, ancak standart bir tedavi rejimi ve genel kabul görmüş bir sınıflama yapılmamıştır. Yenidoğanların ağızları pek çok özelliği bakımından özgündür ve doğum periyodundaki gelişimsel olaylara bağlı olarak meydana gelen lezyonlar genellikle iyi huylu mukozal durumları içermektedir. Çalışmalarda; Bohn nodülleri, Epstein incileri ve gingival kistler en sık görülen kistik lezyonlar iken, enfeksiyona bağlı olarak en çok kandida ve herpes simpleks virüsleri ile ilişkili orolabial lezyonlar görülmektedir. Ek olarak, travmaya bağlı lezyonlar, hemanjiyom, lenfanjiyom, konjenital epulis gibi tümöral durumlar, pemfigus vulgaris gibi otoimmün hastalıklar, coğrafi dil, ankiloglossi, makroglossi gibi benign durumlar ve malign melanom ve rabdomiyosarkom gibi malign neoplazmalar da oral bölgelerde gözlenebilmektedir. Oral mukozal lezyonlar, özellikle yenidoğanlarda ve çocuklarda sistemik hastalıkların erken teşhisi için ipucu olabilir. Bundan dolayı yanlış tedavi ve araştırmalardan kaçınmak, doğru tanıya ulaşmak için görülebilecek tüm lezyonlar hakkında bilgi sahibi olmak gerekmektedir. Oral bölgede meydana gelen bir lezyonda endişeli ebeveynlerin başvuracağı merkezlerin başında diş hekimleri gelmektedir. Bunun yanında, yenidoğan oral lezyonlarıyla ilgili literatürdeki çalışma sayısı oldukça azdır ve bu çalışmada, klinikte karşımıza çıkabilecek lezyonlar, bu lezyonların görülme sıklıkları, etiyolojileri, klinik bulguları, ayırıcı tanıları ve tedavi yöntemlerinin bir araya toplanması amaçlanmıştır.
Anahtar Kelimeler: Yenidoğan; ağız mukozası; ağız hastalıkları; ağız neoplazileri
Oral lesions are rarely seen in neonates, but they are closely related to dentists, pediatricians and dermatologists. Studies have been conducted to classify these oral lesions, but a standard treatment regimen and a generally accepted classification have not been performed. Newborns' mouths are unique in terms of many features, and the lesions that occur due to developmental events in the period of birth usually involve benign mucosal conditions. While Bohn's nodules, Epstein pearls and gingival cysts are the most frequently observed cystic lesions in studies, orabial lesions related to candida and herpes simplex viruses are mostly observed in relation to infection. In addition to these, tumoral cases such as lesions caused by trauma, hemangioma, lymphangioma and congenital epulis; autoimmune illnesses such as pemphigus vulgaris; benign situations such as geographical tongue, ankyloglossia, macroglossia and malign neoplasms such as malignant melanoma and rhabdomyosarcoma are also observed in oral areas. Oral mucosal lesions may be a clue for early diagnosis of systemic diseases, especially in newborns and children. Therefore, it is necessary to avoid inappropriate treatment and investigation and to have information about all the lesions that can be seen in order to reach the correct diagnosis. In the case of a lesion that occurs in the oral region, dentists are the primary centers of concern for parents. In addition, the number of studies on neonatal oral lesions in the literature is very few, and in this review, the lesions that may be encountered in the clinic, the incidence, etiology, clinical findings, differential diagnoses and treatment methods of these lesions were collected.
Keywords: Newborn; mouth mucosa; mouth diseases; mouth neoplasms
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