.: ORİJİNAL ARAŞTIRMA
The Severity of Chronic Obstructive Pulmonary Disease Affect Lower Urinary Tract Symptoms and Sexual Function
Kronik Obstrüktif Akciğer Hastalığının Şiddeti Alt Üriner Sistem Semptomlarını ve Cinsel Fonksiyonu Etkilemektedir
J Reconstr Urol. 2021;11(1):7-11
doi: 10.5336/urology.2020-80457
Makale Dili: EN
Tam Metin
ABSTRACT
Objective: The present study aimed to investigate the incidence of lower urinary tract symptoms, overactive bladder (OAB) syndrome, and erectile dysfunction (ED) in chronic obstructive pulmonary disease (COPD) patients. Material and Methods: The study included a total of 707 male patients with COPD. The Overactive Bladder Questionnaire, the International Prostate Symptom Score (IPSS), and the International Index of Erectile Function (IIEF) were administered to each patient. Additionally, each patient was also queried as to whether they had any loss of libido. Pulmonary examination was performed based on physical examination findings, spirometric measurements, and arterial blood gas analyses. Results: Mean age of the patients was 52.5±10.6 years and a significant relationship was found between patient age and ED and lower urinary tract symptoms (p=0.01). Mean body mass index (BMI) was 33.2±5.6 kg/m2 . A significant relationship was found between BMI >35 kg/m2 and ED (p=0.042). Mean OAVB-V8 score was 7.71±4.44. Mean IPSS score was 10.3±5.7 and mean IIEF score was found to be 11.6±6.44. A significant relationship was established between severe and most severe COPD and lower urinary tract symptoms including urgency and urge incontinence (p=0.035 and p=0.021, respectively). A significant relationship was detected between COPD severity and ED (p=0.001). Moreover, the incidence of ED was higher in patients with oxygen saturation of ≤90 (p=0.044). Normal libido was reported by 91% of the patients. Conclusion: Our results indicated that the prevalence of ED is increased in patients with severe and most severe COPD and that the prevalence of lower urinary tract symptoms (especially urge incontinence and urgency) is higher in COPD patients.
Keywords: Pulmonary disease; chronic obstructive erectile dysfunction; lower urinary tract symptoms; libido; urinary bladder, overactive
Objective: The present study aimed to investigate the incidence of lower urinary tract symptoms, overactive bladder (OAB) syndrome, and erectile dysfunction (ED) in chronic obstructive pulmonary disease (COPD) patients. Material and Methods: The study included a total of 707 male patients with COPD. The Overactive Bladder Questionnaire, the International Prostate Symptom Score (IPSS), and the International Index of Erectile Function (IIEF) were administered to each patient. Additionally, each patient was also queried as to whether they had any loss of libido. Pulmonary examination was performed based on physical examination findings, spirometric measurements, and arterial blood gas analyses. Results: Mean age of the patients was 52.5±10.6 years and a significant relationship was found between patient age and ED and lower urinary tract symptoms (p=0.01). Mean body mass index (BMI) was 33.2±5.6 kg/m2 . A significant relationship was found between BMI >35 kg/m2 and ED (p=0.042). Mean OAVB-V8 score was 7.71±4.44. Mean IPSS score was 10.3±5.7 and mean IIEF score was found to be 11.6±6.44. A significant relationship was established between severe and most severe COPD and lower urinary tract symptoms including urgency and urge incontinence (p=0.035 and p=0.021, respectively). A significant relationship was detected between COPD severity and ED (p=0.001). Moreover, the incidence of ED was higher in patients with oxygen saturation of ≤90 (p=0.044). Normal libido was reported by 91% of the patients. Conclusion: Our results indicated that the prevalence of ED is increased in patients with severe and most severe COPD and that the prevalence of lower urinary tract symptoms (especially urge incontinence and urgency) is higher in COPD patients.
Keywords: Pulmonary disease; chronic obstructive erectile dysfunction; lower urinary tract symptoms; libido; urinary bladder, overactive
ÖZET
Amaç: Bu çalışmada, kronik obstrüktif akciğer hastalığı (KOAH) olan hastalarda alt üriner sistem semptomları, aşırı aktif mesane [overactive bladder (OAB)] sendromu ve erektil disfonksiyon (ED) görülme sıklığı araştırıldı. Gereç ve Yöntemler: Çalışmaya KOAH'lı toplam 707 erkek hasta dâhil edildi. Her hastaya Aşırı Aktif Mesane Anketi, Uluslararası Prostat Semptom Skoru [International Prostate Symptom Score (IPSS)] ve Uluslararası Erektil Fonksiyon İndeksi [International Index of Erectile Function (IIEF)] formu dolduruldu. Ek olarak, her hasta libido kaybı olup olmadığı konusunda da sorgulandı. Akciğer muayenesi; fizik muayene bulguları, spirometrik ölçümler ve arteriyel kan gazı analizleri ile yapıldı. Bulgular: Hastaların ortalama yaşı 52,5±10,6 yıl idi ve hasta yaşı ile ED ve alt üriner sistem semptomları arasında anlamlı bir ilişki bulundu (p=0,01). Ortalama beden kitle indeksi (BKİ) 33,2±5,6 kg/m2 idi. BKİ> 35 kg/m2 ile ED arasında anlamlı bir ilişki bulundu (p=0,042). Ortalama OAVBV8 skoru 7,71±4,44, ortalama IPSS skoru 10,3±5,7 ve ortalama IIEF skoru 11,6±6,44 bulundu. Şiddetli ve ileri KOAH ile acil ve idrar kaçırma da dâhil olmak üzere alt üriner sistem semptomları arasında anlamlı bir ilişki bulundu (sırasıyla p=0,035 ve p=0,021). KOAH şiddeti ile ED arasında anlamlı ilişki saptandı (p=0,001). Ayrıca, oksijen saturasyonu ≤90 olan hastalarda ED insidansı daha yüksek bulundu (p=0,044). Hastaların %91'inde normal libidonun normal olduğu görüldü. Sonuç: Sonuçlarımız şiddetli ve ileri şiddetli KOAH'lı hastalarda ED prevalansının arttığını ve KOAH hastalarında alt üriner sistem semptomlarının (özellikle urge inkontinans ve urgency) prevalansının daha yüksek olduğunu göstermiştir.
Anahtar Kelimeler: Pulmoner hastalık; kronik obstrüktif sertleşme bozukluğu; alt üriner sistem semptomları; libido; mesane, aşırı aktif
Amaç: Bu çalışmada, kronik obstrüktif akciğer hastalığı (KOAH) olan hastalarda alt üriner sistem semptomları, aşırı aktif mesane [overactive bladder (OAB)] sendromu ve erektil disfonksiyon (ED) görülme sıklığı araştırıldı. Gereç ve Yöntemler: Çalışmaya KOAH'lı toplam 707 erkek hasta dâhil edildi. Her hastaya Aşırı Aktif Mesane Anketi, Uluslararası Prostat Semptom Skoru [International Prostate Symptom Score (IPSS)] ve Uluslararası Erektil Fonksiyon İndeksi [International Index of Erectile Function (IIEF)] formu dolduruldu. Ek olarak, her hasta libido kaybı olup olmadığı konusunda da sorgulandı. Akciğer muayenesi; fizik muayene bulguları, spirometrik ölçümler ve arteriyel kan gazı analizleri ile yapıldı. Bulgular: Hastaların ortalama yaşı 52,5±10,6 yıl idi ve hasta yaşı ile ED ve alt üriner sistem semptomları arasında anlamlı bir ilişki bulundu (p=0,01). Ortalama beden kitle indeksi (BKİ) 33,2±5,6 kg/m2 idi. BKİ> 35 kg/m2 ile ED arasında anlamlı bir ilişki bulundu (p=0,042). Ortalama OAVBV8 skoru 7,71±4,44, ortalama IPSS skoru 10,3±5,7 ve ortalama IIEF skoru 11,6±6,44 bulundu. Şiddetli ve ileri KOAH ile acil ve idrar kaçırma da dâhil olmak üzere alt üriner sistem semptomları arasında anlamlı bir ilişki bulundu (sırasıyla p=0,035 ve p=0,021). KOAH şiddeti ile ED arasında anlamlı ilişki saptandı (p=0,001). Ayrıca, oksijen saturasyonu ≤90 olan hastalarda ED insidansı daha yüksek bulundu (p=0,044). Hastaların %91'inde normal libidonun normal olduğu görüldü. Sonuç: Sonuçlarımız şiddetli ve ileri şiddetli KOAH'lı hastalarda ED prevalansının arttığını ve KOAH hastalarında alt üriner sistem semptomlarının (özellikle urge inkontinans ve urgency) prevalansının daha yüksek olduğunu göstermiştir.
Anahtar Kelimeler: Pulmoner hastalık; kronik obstrüktif sertleşme bozukluğu; alt üriner sistem semptomları; libido; mesane, aşırı aktif
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