.: ORİJİNAL ARAŞTIRMA
The Assessment of Age-Related Changes in Anterior Segment Parameters Measured by Dual Scheimpflug Analyzer
Yaşla Beraber Ön Segment Parametrelerindeki Değişimin Dual Scheimpflug Topografi ile Değerlendirilmesi
Turkiye Klinikleri J Ophthalmol. 2020;29(1):31-7
doi: 10.5336/ophthal.2019-64912
Makale Dili: EN
Tam Metin
ABSTRACT
Objective: The aim of this study was to investigate the changes according to age in anterior segment parameters measured by Galilei Dual Scheimpflug Analyzer. Material and Methods: Healthy subjects were recruited and classified into seven groups according to age. Group 1 consisted of subjects whose ages ranged between 5 and 10 years. Group 2, 3, 4, 5, 6, 7 consisted of subjects who were in their second, third, forth, fifth, sixth and seventh decades, respectively. After a detailed examination, anterior segment parameters were assessed by using Galilei Dual Scheimpflug Analyzer. The following parameters were obtained from topographic and pachymetric maps for analysis: anterior chamber angle (ACA), anterior chamber depth (ACD), anterior chamber volume (ACV), central corneal thickness (CCT), pupil diameter (PD) and corneal horizontal diameter (CHD). Statistical analysis was performed by using SPSS for Windows version 23.0. Results: The age of subjects ranged between 5 and 67 years. Of 229 subjects, 152 (66.4%) were female and 77 (33.6%) were male. The decrease in CCT, CHD, PD, ACD and ACA with age was statistically significant and a negative correlation was present (p=0.000). Except Group 1, the decline in ACV by increasing age was statistically significant and a negative correlation was present [r (458) =-0.34. p=0.000]. Conclusion: All anterior segment parameters except mean ACV measured by Galilei Dual Scheimpflug Analyzer were found to decline with age and mean ACD achieved to adult size till the beginning of the second decade.
Keywords: Dual scheimpflug analyzer; anterior segment parameters; age
Objective: The aim of this study was to investigate the changes according to age in anterior segment parameters measured by Galilei Dual Scheimpflug Analyzer. Material and Methods: Healthy subjects were recruited and classified into seven groups according to age. Group 1 consisted of subjects whose ages ranged between 5 and 10 years. Group 2, 3, 4, 5, 6, 7 consisted of subjects who were in their second, third, forth, fifth, sixth and seventh decades, respectively. After a detailed examination, anterior segment parameters were assessed by using Galilei Dual Scheimpflug Analyzer. The following parameters were obtained from topographic and pachymetric maps for analysis: anterior chamber angle (ACA), anterior chamber depth (ACD), anterior chamber volume (ACV), central corneal thickness (CCT), pupil diameter (PD) and corneal horizontal diameter (CHD). Statistical analysis was performed by using SPSS for Windows version 23.0. Results: The age of subjects ranged between 5 and 67 years. Of 229 subjects, 152 (66.4%) were female and 77 (33.6%) were male. The decrease in CCT, CHD, PD, ACD and ACA with age was statistically significant and a negative correlation was present (p=0.000). Except Group 1, the decline in ACV by increasing age was statistically significant and a negative correlation was present [r (458) =-0.34. p=0.000]. Conclusion: All anterior segment parameters except mean ACV measured by Galilei Dual Scheimpflug Analyzer were found to decline with age and mean ACD achieved to adult size till the beginning of the second decade.
Keywords: Dual scheimpflug analyzer; anterior segment parameters; age
ÖZET
Amaç: Yaşla beraber ön segment parametrelerindeki değişimin Galilei Dual Scheimpflug Topografi ile değerlendirilmesi. Gereç ve Yöntemler: Çalışmaya sağlıklı denekler alınarak yaşlarına göre 7 gruba ayrıldı. Grup 1'deki deneklerin yaşları 5 ile 10 arasında idi. Grup 2, 3, 4, 5, 6 ve 7 ise yaşları sırasıyla ikinci, üçüncü, dördüncü, beşinci, altıncı ve yedinci on yıllarında olan deneklerden oluşturuldu. Detaylı göz muayenesinden sonra Galilei Dual Scheimpflug Topografi ile ön segment parametreleri değerlendirildi. Ön kamara açısı (ÖKA), ön kamara derinliği (ÖKD), ön kamara hacmi (ÖKH), merkezi kornea kalınlığı (MKK), pupilla çapı (PÇ) ve horizontal kornea çapı (KÇ) değerleri topografik ve pakimetrik haritalar incelenerek değerlendirildi. İstatistiksel analiz SPSS 23,0 programı ile yapıldı. Bulgular: Çalışmaya katılan 229 deneğin yaşları 5 ile 67 arasında değişmekte ve 152'si (%66,4) kadın, 77'si (%33,6) ise erkekti. Analiz sonucunda MKK, KÇ, PÇ, ÖKD ve ÖKA yaşla beraber azalmakta ve yaş ile bu değerler arasında istatistiksel olarak negatif korelasyon mevcuttu (p=0,000). ÖKH'de ise Grup 1 hariç diğer gruplar arasında yaşla beraber düşme olduğu gözlenmiş ve istatistiksel olarak negatif korelasyon bulunmuştur [r (458) =-0,34. p=0,000]. Sonuç: Galilei Dual Scheimpflug topografi ile ortalama ÖKH hariç tüm ön segment parametreleri yaşla birlikte azalmıştır. ÖKD'nin ikinci on yıldan itibaren erişkin boyutuna ulaştığı gözlenmiştir.
Anahtar Kelimeler: Dual scheimpflug topografi; ön segment parametreleri; yaş
Amaç: Yaşla beraber ön segment parametrelerindeki değişimin Galilei Dual Scheimpflug Topografi ile değerlendirilmesi. Gereç ve Yöntemler: Çalışmaya sağlıklı denekler alınarak yaşlarına göre 7 gruba ayrıldı. Grup 1'deki deneklerin yaşları 5 ile 10 arasında idi. Grup 2, 3, 4, 5, 6 ve 7 ise yaşları sırasıyla ikinci, üçüncü, dördüncü, beşinci, altıncı ve yedinci on yıllarında olan deneklerden oluşturuldu. Detaylı göz muayenesinden sonra Galilei Dual Scheimpflug Topografi ile ön segment parametreleri değerlendirildi. Ön kamara açısı (ÖKA), ön kamara derinliği (ÖKD), ön kamara hacmi (ÖKH), merkezi kornea kalınlığı (MKK), pupilla çapı (PÇ) ve horizontal kornea çapı (KÇ) değerleri topografik ve pakimetrik haritalar incelenerek değerlendirildi. İstatistiksel analiz SPSS 23,0 programı ile yapıldı. Bulgular: Çalışmaya katılan 229 deneğin yaşları 5 ile 67 arasında değişmekte ve 152'si (%66,4) kadın, 77'si (%33,6) ise erkekti. Analiz sonucunda MKK, KÇ, PÇ, ÖKD ve ÖKA yaşla beraber azalmakta ve yaş ile bu değerler arasında istatistiksel olarak negatif korelasyon mevcuttu (p=0,000). ÖKH'de ise Grup 1 hariç diğer gruplar arasında yaşla beraber düşme olduğu gözlenmiş ve istatistiksel olarak negatif korelasyon bulunmuştur [r (458) =-0,34. p=0,000]. Sonuç: Galilei Dual Scheimpflug topografi ile ortalama ÖKH hariç tüm ön segment parametreleri yaşla birlikte azalmıştır. ÖKD'nin ikinci on yıldan itibaren erişkin boyutuna ulaştığı gözlenmiştir.
Anahtar Kelimeler: Dual scheimpflug topografi; ön segment parametreleri; yaş
REFERANSLAR:
- Altan C, Bayraktar S, Altan T, Eren H, Yilmaz OF. Anterior chamber depth, iridocorneal angle width, and intraocular pressure changes after uneventful phacoemulsification in eyes without glaucoma and with open iridocorneal angles. J Cataract Refract Surg. 2004;30(4):832-8. [Crossref] [PubMed]
- Auffarth GU, Wang L, Völcker HE. Keratoconus evaluation using the Orbscan topography system. J Cataract Refract Surg. 2000;26(2):222-8. [Crossref]
- Behndig A, Markström K. Determination of the aqueous humour volume by three dimensional mapping of the anterior chamber. Ophthalmic Res. 2005;37(1):13-6. [Crossref] [PubMed]
- Pflugfelder SC, Liu Z, Feuer W, Verm A. Corneal thickness indices discriminate between keratoconus and contact lens induced corneal thinning. Ophthalmology. 2002;109(12):2336-41. [Crossref]
- Javaloy J, Vidal MT, Villada JR, Artola A, Alióet JL. Comparison of four corneal pachymetry techniques in corneal refractive surgery. J Refract Surg. 2004;20(1):29-34. [Crossref] [PubMed]
- Rüfer F, Schröder A, Bader C, Erb C. Age-related changes in central and peripheral corneal thickness. Cornea. 2007;26(1):1-5. [Crossref] [PubMed]
- Hoerauf H, Wirbelauer C, Scholz C, Engelhardt R, Koch P, Laqua H, et al. Slitlamp adapted optical coherence tomography of the anterior segment. Graefes Arch Clin Exp Ophthalmol. 2000;238(1):8-18. [Crossref] [PubMed]
- Shankar H, Taranath D, Santhirathelagan CT, Pesudovs K. Anterior segment biometry with the Pentacam: comprehensive assessment of repeatability of automated measurements. J Cataract Refract Surg. 2008;34(1):103-13. [Crossref] [PubMed]
- Cosar CB, Sener AB. Orbscan corneal topography system in evaluating the anterior structures of the human eye. Cornea. 2003;22(2):118-21. [Crossref] [PubMed]
- Savini G, Carbonelli M, Barboni P, Hoffer KJ. Repeatability of automatic measurements performed by a dual Scheimpflug analyzer in unoperated and post-refractive surgery eyes. J Cataract Refract Surg. 2011;37(2):302-9. [Crossref] [PubMed]
- Jonsson M, Markström K, Behndig A. Slit-scan tomography evaluation of the anterior chamber and corneal configurations at different ages. Acta Ophthalmol Scand. 2006;84(1): 116-20. [Crossref] [PubMed]
- Hashmani N, Hashmani S, Hanfi AN, Ayub M, Saad CM, Rajani H, et al. Effect of age, sex, and refractive errors on central corneal thickness measured by Oculus Pentacam®. Clin Ophthalmol. 2017;11:1233-8. [Crossref] [PubMed] [PMC]
- Atchison DA, Markwell EL, Kasthurirangan S, Pope JM, Smith G, Swann PG. Age-related changes in optical and biometric characteristics of emmetropic eyes. J Vis. 2008;8(29):1-20. [Crossref] [PubMed]
- Prasad A, Fry K, Hersh PS. Relationship of age and refraction to central corneal thickness. Cornea. 2011;30(5):553-5. [Crossref] [PubMed]
- Altinok A, Sen E, Yazici A, Aksakal FN, Oncul H, Koklu G. Factors influencing central corneal thickness in a Turkish population. Curr Eye Res. 2007;32(5):413-9. [Crossref] [PubMed]
- Cho P, Lam C. Factors affecting the central corneal thickness of Hong Kong-Chinese. Curr Eye Res. 1999;18(5):368-74. [Crossref] [PubMed]
- Guillon M, Dumbleton K, Theodoratos P, Gobbe M, Wooley CB, Moody K. The effects of age, refractive status, and luminance on pupil size. Optom Vis Sci. 2016;93(9):1093-100. [Crossref] [PubMed] [PMC]
- Yan PS, Lin HT, Wang QL, Zhang ZP. Anterior segment variations with age and accommodation demonstrated by slit-lamp-adapted optical coherence tomography. Ophthalmology. 2010;117(12):2301-7. [Crossref] [PubMed]
- Chang DH, Davis EA. Phakic intraocular lenses. Curr Opin Ophthalmol. 2006;17(1):99-104. [Crossref] [PubMed]
- Sanders DR, Vukich JA, Doney K, Gaston M; Implantable Contact Lens in Treatment of Myopia (ITM) Study Group. U.S. Food and Drug Administration clinical trial of the implantable contact lens for moderate to high myopia. Ophthalmology. 2003;110(2):255-66. [Crossref]
- Sanders DR, Doney K, Poco M; ICL in Treatment of Myopia (ITM) Study Group. United States Food and Drug Administration clinical trial of the Implantable Collamer Lens (ICL) for moderate to high myopia: three-year follow-up. Ophthalmology. 2004;111(9):1683-92. [Crossref] [PubMed]
- Dalal LK, Dhasmana R, Maitreya A. Cross-sectional, observational study of anterior segment parameters using anterior segment optical coherence tomography in north indian population. Ann Afr Med. 2017;16(3):131-5. [Crossref] [PubMed] [PMC]
- Orucoglu F, Akman M, Onal S. Analysis of age, refractive error and gender related changes of the cornea and the anterior segment of the eye with Scheimpflug imaging. Cont Lens Anterior Eye. 2015;38(5):345-50. [Crossref] [PubMed]
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