Amaç: Koroner arter baypas greft cerrahisi geçiren hastalarda uzamış ekstübasyon süreleri postoperatif komplikasyonlar, morbidite ve mortalite artışı, yoğun bakım ünitesi ve hastanede kalış sürelerinin uzaması ile ilişkilidir. Bu çalışmada, koroner arter baypas greft cerrahisi geçiren hastalarda ekstübasyon süresine etki eden faktörlerin belirlenmesi amaçlamıştır. Gereç ve Yöntemler: Bu retrospektif kesitsel çalışmaya elektif şartlarda izole koroner arter baypas greft cerrahisi uygulanmış olan 81 hasta dâhil edildi. Hastalar ekstübe edildikleri saate göre gruplandırıldı. Yoğun bakım ünitesinde 6 saatten önce ekstübe edilenler Grup 1'e (n=49); 6 saatten sonra ekstübe edilenler ise Grup 2'ye dâhil edildi (n=32). Bulgular: Grup 2'deki hastaların preoperatif hematokrit değerlerinin daha düşük (p=0,02); pre (p=0,02) ve postoperatif kan üre nitrojeni (p<0,001) ve postoperatif kreatinin (p=0,001) düzeylerinin ise Grup 1'e göre daha yüksek olduğu saptandı. Ayrıca intraoperatif ultrafiltrasyon ihtiyacı olanların (p=0,02) daha geç ekstübe olduğu ve Grup 2'deki hastalara postoperatif dönemde daha fazla eritrosit süspansiyonu (p<0,001) ve taze donmuş plazma (p=0,003) replasmanının yapıldığı saptandı. Son olarak Grup 2'deki hastaların yoğun bakım ünitesi (p=0,002) ve hastane kalış süreleri (p=0,056) daha uzun olarak saptandı. Sonuç: Koroner arter baypas greft cerrahisi geçiren hastalarda postoperatif ekstübasyon süresine etki edebilecek faktörlere dikkat edilmesi hastaların daha kısa sürede ekstübe edilmesine katkı sunacaktır. Bu da postoperatif morbidite ve mortalitenin azalması ve yoğun bakım ünitesi ile hastanede kalış sürelerinin kısalmasına katkı sunacaktır.
Anahtar Kelimeler: Koroner arter baypas greft; ekstübasyon; yoğun bakım ünitesi
Objective: Prolonged extubation times in patients undergoing coronary artery bypass grafting are associated with increased postoperative complications, morbidity, and mortality, as well as prolonged intensive care unit and hospital stays. This study aimed to identify the factors affecting extubation time in patients undergoing coronary artery bypass grafting surgery. Material and Methods: This retrospective cross-sectional study included 81 patients who underwent elective isolated coronary artery bypass grafting surgery. The patients were grouped based on their extubation time. Those extubated within 6 hours in the intensive care unit were classified as Group 1 (n=49), while those extubated after 6 hours were classified as Group 2 (n=32). Results: Patients in Group 2 had lower preoperative hematocrit levels (p=0.02), higher preoperative (p=0.02) and postoperative blood urea nitrogen (p<0.001), and higher postoperative creatinine (p=0.001) levels compared to Group 1. Additionally, patients who required intraoperative ultrafiltration (p=0.02) had delayed extubation, and more erythrocyte suspension (p<0.001) and fresh frozen plasma (p=0.003) transfusions were administered postoperatively in Group 2. Lastly, intensive care unit (p=0.002) and hospital stays (p=0.056) were longer in Group 2. Conclusion: Paying attention to factors that may affect postoperative extubation time in patients undergoing coronary artery bypass grafting surgery can contribute to earlier extubation. This may help reduce postoperative morbidity and mortality, as well as intensive care unit and hospital stay durations.
Keywords: Coronary artery bypass grafting; extubation; intensive care unit
- World Health Organization [Internet]. © 2024 WHO [Cited: September 24, 2024]. Cardiovascular diseases (CVDs). Available from: [Link]
- Crawford TC, Magruder JT, Grimm JC, Sciortino C, Conte JV, Kim BS, et al. Early extubation: a proposed new metric. Semin Thorac Cardiovasc Surg. 2016;28(2):290-9. [Crossref] [PubMed]
- E Silva RAG, Borgomoni GB, Maia ADS, do Vale Juniora CF, Pereira EDS, Silvestre LGI, et al; Grupo de estudos REPLICCAR. Extubation in the operating room after coronary artery bypass graft surgery reduces hospital stay. J Cardiothorac Vasc Anesth. 2023;37(10):1938-45. [Crossref] [PubMed]
- Grant MC, Crisafi C, Alvarez A, Arora RC, Brindle ME, Chatterjee S, et al. Perioperative Care in Cardiac Surgery: A Joint Consensus Statement by the Enhanced Recovery After Surgery (ERAS) Cardiac Society, ERAS International Society, and The Society of Thoracic Surgeons (STS). Ann Thorac Surg. 2024;117(4):669-89. Erratum in: Ann Thorac Surg. 2024;118(2):524-5. [Crossref] [PubMed]
- Daza-Arana JE, Lozada-Ramos H, Ávila-Hernández DF, Ordoñez-Mora LT, Sánchez DP. Prolonged mechanical ventilation following coronary artery bypass graft in Santiago De Cali, Colombia. Vasc Health Risk Manag. 2022;18:767-81. [Crossref] [PubMed] [PMC]
- Lima CA, Ritchrmoc MK, Leite WS, Silva DARG, Lima WA, Campos SL, et al. Impact of fast-track management on adult cardiac surgery: clinical and hospital outcomes. Rev Bras Ter Intensiva. 2019;31(3):361-7. Erratum in: Rev Bras Ter Intensiva. 2020;32(2):332. [Crossref] [PubMed] [PMC]
- Goeddel LA, Hollander KN, Evans AS. Early Extubation after cardiac surgery: a better predictor of outcome than metric of quality? J Cardiothorac Vasc Anesth. 2018;32(2):745-7. [Crossref] [PubMed]
- Faraoni D, Ng WCK. Pro: early extubation after pediatric cardiac surgery. J Cardiothorac Vasc Anesth. 2020;34(9):2539-41. [Crossref] [PubMed]
- Fitch ZW, Debesa O, Ohkuma R, Duquaine D, Steppan J, Schneider EB, et al. A protocol-driven approach to early extubation after heart surgery. J Thorac Cardiovasc Surg. 2014;147(4):1344-50. [Crossref] [PubMed]
- Taylor M, Apparau D, Mosca R, Nwaejike N. Does early extubation after cardiac surgery lead to a reduction in intensive care unit length of stay? Interact Cardiovasc Thorac Surg. 2022;34(5):731-4. [Crossref] [PubMed] [PMC]
- Grocott HP. Early extubation after cardiac surgery: the evolution continues. J Thorac Cardiovasc Surg. 2017;154(5):1654-5. [Crossref] [PubMed]
- Shahbazi S, Kazerooni M. Predictive factors for delayed extubation in the intensive care unit after coronary artery bypass grafting; a southern Iranian experience. Iran J Med Sci. 2012;37(4):238-41. [PubMed] [PMC]
- Walthall H, Robson D, Ray S. Do any preoperative variables affect extubation time after coronary artery bypass graft surgery? Heart Lung. 2001;30(3):216-24. [Crossref] [PubMed]
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