.: ORİJİNAL ARAŞTIRMA
Hipermetropik Anizometropik Ambliyopide Retina Tabakalarının Optik Koherens Tomografi Segmentasyon Analizi ile Değerlendirilmesi
Evaluation of Retinal Layers in Hyperopic Anisometropic Amblyopia by Optical Coherence Tomography Segmentation Analysis
Turkiye Klinikleri J Ophthalmol. 2020;29(3):192-8
doi: 10.5336/ophthal.2019-71477
Makale Dili: TR
Tam Metin
ÖZET
Amaç: Hipermetropik anizometropik ambliyopisi olan olgularda spektral domain optik koherens tomografi (OKT) kullanarak retina tabakalarını analiz etmek ve ambliyopik gözlerle normal gözleri kıyaslamak. Gereç ve Yöntemler: Detaylı oftalmolojik muayeneyi takiben hipermetropik anizometropik ambliyopisi olan olguların her iki gözü OKT ile değerlendirildi. Merkezi makula kalınlığı (MMK) analizi sonrasında, ganglion hücre tabakası, iç pleksiform tabaka, iç nükleer tabaka, dış pleksiform tabaka, dış nükleer tabaka ve retina pigment epiteli tabakasına ait ortalama kalınlıklar kaydedildi. Retinal katmanlar ayrıca iç ve dış retina katmanlar olmak üzere 2 katmana ayrılarak analiz edildi. Bulgular: Yirmi (%33,3)'si kadın, 40 (%66,7)'ı erkek hipermetropik anizometropik ambliyopiden oluşan olguların ortalama yaşı 17,3±9,0 olarak hesaplandı. Ortalama MMK ambliyopik gözlerde 27030±1815 µm, normal gözlerde ise 265,13±19,25 µm olarak hesaplandı. Ambliyopik gözlerde MMK'nin normal gözlere kıyasla istatistiksel olarak anlamlı düzeyde kalın olduğu saptandı (p0,05, her biri için). Sonuç: Hipermetropik anizometropik ambliyopisi olan olgularda ambliyopik gözlerde normal gözlere kıyasla merkezi makulanın anlamlı düzeyde daha kalın olduğu saptanırken, retina tabakaları kalınlıkları arasında istatistiksel olarak anlamlı bir fark bulunmamıştır.
Anahtar Kelimeler: Ambliyopi; anizometropi; optik koherens tomografi
Amaç: Hipermetropik anizometropik ambliyopisi olan olgularda spektral domain optik koherens tomografi (OKT) kullanarak retina tabakalarını analiz etmek ve ambliyopik gözlerle normal gözleri kıyaslamak. Gereç ve Yöntemler: Detaylı oftalmolojik muayeneyi takiben hipermetropik anizometropik ambliyopisi olan olguların her iki gözü OKT ile değerlendirildi. Merkezi makula kalınlığı (MMK) analizi sonrasında, ganglion hücre tabakası, iç pleksiform tabaka, iç nükleer tabaka, dış pleksiform tabaka, dış nükleer tabaka ve retina pigment epiteli tabakasına ait ortalama kalınlıklar kaydedildi. Retinal katmanlar ayrıca iç ve dış retina katmanlar olmak üzere 2 katmana ayrılarak analiz edildi. Bulgular: Yirmi (%33,3)'si kadın, 40 (%66,7)'ı erkek hipermetropik anizometropik ambliyopiden oluşan olguların ortalama yaşı 17,3±9,0 olarak hesaplandı. Ortalama MMK ambliyopik gözlerde 27030±1815 µm, normal gözlerde ise 265,13±19,25 µm olarak hesaplandı. Ambliyopik gözlerde MMK'nin normal gözlere kıyasla istatistiksel olarak anlamlı düzeyde kalın olduğu saptandı (p0,05, her biri için). Sonuç: Hipermetropik anizometropik ambliyopisi olan olgularda ambliyopik gözlerde normal gözlere kıyasla merkezi makulanın anlamlı düzeyde daha kalın olduğu saptanırken, retina tabakaları kalınlıkları arasında istatistiksel olarak anlamlı bir fark bulunmamıştır.
Anahtar Kelimeler: Ambliyopi; anizometropi; optik koherens tomografi
ABSTRACT
Objective: To analyse the retinal layers using spectral domain optical coherence tomography (OCT) in patients with hypermetropic anisometropic amblyopia and to compare amblyopic eyes with normal eyes. Material and Methods: Following detailed ophthalmological examination, both eyes of the participants with hypermetropic anisometropic amblyopia were evaluated by OCT. After the analysis of central macular thickness (CMT), mean thicknesses of ganglion cell layer, inner plexiform layer, inner nuclear layer, outer plexiform layer, outer nuclear layer and retinal pigment epithelium layer were recorded. The retinal layers were further divided into two layers as inner and outer retinal layers. Results: The mean age of 20 (33.3%) female and 40 (66.7%) male patients with hypermetropic anisometropic amblyopia was 17,3±9.0 years. The mean CMT was 270.30±18.15 µm in amblyopic eyes and 265.1±19.25 µm in normal eyes. In amblyopic eyes, CMT was found to be statistically significantly thicker in amblyopic eyes than normal eyes (p0.05, for each). Conclusion: The central macula was significantly thicker in amblyopic eyes than in normal eyes in patients with hypermetropic anisometropic amblyopia, but there were no statistically significant differences between the retinal layer thicknesses.
Keywords: Amblyopia; anisometropia; optical coherence tomography
Objective: To analyse the retinal layers using spectral domain optical coherence tomography (OCT) in patients with hypermetropic anisometropic amblyopia and to compare amblyopic eyes with normal eyes. Material and Methods: Following detailed ophthalmological examination, both eyes of the participants with hypermetropic anisometropic amblyopia were evaluated by OCT. After the analysis of central macular thickness (CMT), mean thicknesses of ganglion cell layer, inner plexiform layer, inner nuclear layer, outer plexiform layer, outer nuclear layer and retinal pigment epithelium layer were recorded. The retinal layers were further divided into two layers as inner and outer retinal layers. Results: The mean age of 20 (33.3%) female and 40 (66.7%) male patients with hypermetropic anisometropic amblyopia was 17,3±9.0 years. The mean CMT was 270.30±18.15 µm in amblyopic eyes and 265.1±19.25 µm in normal eyes. In amblyopic eyes, CMT was found to be statistically significantly thicker in amblyopic eyes than normal eyes (p0.05, for each). Conclusion: The central macula was significantly thicker in amblyopic eyes than in normal eyes in patients with hypermetropic anisometropic amblyopia, but there were no statistically significant differences between the retinal layer thicknesses.
Keywords: Amblyopia; anisometropia; optical coherence tomography
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