.: ORİJİNAL ARAŞTIRMA
Examination of Clinical Features of COVID-19 Patients in a City Türkiye: A Cross-Sectional Study
Türkiye'de Bir İlde COVID-19 Hastalarının Klinik Özelliklerinin İncelenmesi: Kesitsel Bir Çalışma
Turkiye Klinikleri J Nurs Sci. 2022;14(4):1046-56
doi: 10.5336/nurses.2022-91799
Makale Dili: EN
Tam Metin
ABSTRACT
Objective: The aim of this study was to examine the clinical characteristics of coronavirus disease-2019 (COVID-19) patients, such as their symptoms, laboratory and radiographic results. This is the first study to describe the clinical characteristics of COVID-19 patients in the Eastern Black Sea region of Türkiye. Material and Methods: This is a single-center cross-sectional study. The sample of the study consisted of 556 patients who received inpatient treatment in pandemic clinics and intensive care units with the diagnosis of laboratory-approved COVID-19 infection in a public hospital in XXX province between 20 March 2020-27 August 2020 and whose patient information was recorded in an electronic environment and in the patient files. Results: The mean age of 556 hospitalized patients with COVID-19 was 58.08±17.18 years, and the three most common symptoms were cough (44.4%), fever (20.5%), and fatigue (17.3%). 30.2% of the patients had lymphocytopenia, 67.8% had high C-reactive protein (CRP), 37.9% had high lactate dehydrogenase, and 30.5% had positive D-dimer levels. Symptomatic patients had greater comorbidities and higher CRP levels than asymptomatic patients. High CRP odds ratio 2.069, high ferritin odds ratio 3.605, and platelet odds ratio 0.995 were found to be associated with abnormal thoracic tomography in the logistic regression. Conclusion: This study provides basic data to show the importance of determining the clinical characteristics of COVID-19 patients in the Eastern Black Sea region of Türkiye. Results can be used as a knowledge base for future research and to implement procedures for improving safety perceptions among patients.
Keywords: COVID-19; SARS-CoV-2; Türkiye; clinical characteristics; outbreak
Objective: The aim of this study was to examine the clinical characteristics of coronavirus disease-2019 (COVID-19) patients, such as their symptoms, laboratory and radiographic results. This is the first study to describe the clinical characteristics of COVID-19 patients in the Eastern Black Sea region of Türkiye. Material and Methods: This is a single-center cross-sectional study. The sample of the study consisted of 556 patients who received inpatient treatment in pandemic clinics and intensive care units with the diagnosis of laboratory-approved COVID-19 infection in a public hospital in XXX province between 20 March 2020-27 August 2020 and whose patient information was recorded in an electronic environment and in the patient files. Results: The mean age of 556 hospitalized patients with COVID-19 was 58.08±17.18 years, and the three most common symptoms were cough (44.4%), fever (20.5%), and fatigue (17.3%). 30.2% of the patients had lymphocytopenia, 67.8% had high C-reactive protein (CRP), 37.9% had high lactate dehydrogenase, and 30.5% had positive D-dimer levels. Symptomatic patients had greater comorbidities and higher CRP levels than asymptomatic patients. High CRP odds ratio 2.069, high ferritin odds ratio 3.605, and platelet odds ratio 0.995 were found to be associated with abnormal thoracic tomography in the logistic regression. Conclusion: This study provides basic data to show the importance of determining the clinical characteristics of COVID-19 patients in the Eastern Black Sea region of Türkiye. Results can be used as a knowledge base for future research and to implement procedures for improving safety perceptions among patients.
Keywords: COVID-19; SARS-CoV-2; Türkiye; clinical characteristics; outbreak
ÖZET
Amaç: Bu çalışmanın amacı, koronavirüs hastalığı-2019 [coronavirus disease-2019 (COVID-19)] hastalarının epidemiyolojik ve klinik özelliklerini, laboratuvar bulgularını, radyolojik özelliklerini, tedavisini ve sonuçlarını tanımlamaktır. Gereç ve Yöntemler: Bu, tek merkezli kesitsel bir çalışmadır. Araştırmanın örneklemini, 20 Mart27 Ağustos 2020 tarihleri arasında XXX ilindeki bir hastanede, en az bir numunesi COVID-19 pozitif çıkan, pandemi klinikleri ve yoğun bakım ünitelerinde yatarak tedavi alan ve hasta bilgilerinin elektronik ortamda ya da hasta dosyalarında kayıtlı olduğu 556 hasta oluşturdu. Bulgular: COVID-19 ile hastaneye yatırılan 556 hastanın yaş ortalaması 58,08±17,18 yıl olarak bulunmuştur. En yaygın 3 semptom öksürük (%44,4), ateş (%20,5) ve hâlsizlik (%17,3) olmuştur. Hastaların %30,2'sinde lenfositopeni, %67,8'inde yüksek C-reaktif protein (CRP), %37,9'unda yüksek laktat dehidrogenaz, yaklaşık olarak 1/3'ünde (%30,5) pozitif D-dimer seviyesi tespit edilmiştir. Semptomatik hastaların asemptomatik hastalara göre daha fazla komorbiditeye sahip olduğu bulunmuştur. Semptomatik hastaların CRP düzeyleri, asemptomatik hastalardan daha yüksek bulunmuştur. Yapılan lojistik regresyonda, yüksek CRP odds ratio 2,069, yüksek ferritin odds ratio 3,605 ve trombosit odds ratio 0,995 anormal toraks tomografisi ile ilişkili olduğu saptanmıştır. Sonuç: Bu çalışma, Türkiye'nin Doğu Karadeniz Bölgesi'ndeki COVID19 enfeksiyonu olan hastaların klinik özelliklerin önemini gösteren temel veriler sunmaktadır. Bulgular, gelecekteki araştırmalarda bir bilgi tabanı olarak ve hastalar arasında güvenlik algılarını iyileştirmeye yönelik prosedürleri uygulamak için kullanılabilir.
Anahtar Kelimeler: COVID-19; SARS-CoV-2; Türkiye; klinik özellikler; salgın
Amaç: Bu çalışmanın amacı, koronavirüs hastalığı-2019 [coronavirus disease-2019 (COVID-19)] hastalarının epidemiyolojik ve klinik özelliklerini, laboratuvar bulgularını, radyolojik özelliklerini, tedavisini ve sonuçlarını tanımlamaktır. Gereç ve Yöntemler: Bu, tek merkezli kesitsel bir çalışmadır. Araştırmanın örneklemini, 20 Mart27 Ağustos 2020 tarihleri arasında XXX ilindeki bir hastanede, en az bir numunesi COVID-19 pozitif çıkan, pandemi klinikleri ve yoğun bakım ünitelerinde yatarak tedavi alan ve hasta bilgilerinin elektronik ortamda ya da hasta dosyalarında kayıtlı olduğu 556 hasta oluşturdu. Bulgular: COVID-19 ile hastaneye yatırılan 556 hastanın yaş ortalaması 58,08±17,18 yıl olarak bulunmuştur. En yaygın 3 semptom öksürük (%44,4), ateş (%20,5) ve hâlsizlik (%17,3) olmuştur. Hastaların %30,2'sinde lenfositopeni, %67,8'inde yüksek C-reaktif protein (CRP), %37,9'unda yüksek laktat dehidrogenaz, yaklaşık olarak 1/3'ünde (%30,5) pozitif D-dimer seviyesi tespit edilmiştir. Semptomatik hastaların asemptomatik hastalara göre daha fazla komorbiditeye sahip olduğu bulunmuştur. Semptomatik hastaların CRP düzeyleri, asemptomatik hastalardan daha yüksek bulunmuştur. Yapılan lojistik regresyonda, yüksek CRP odds ratio 2,069, yüksek ferritin odds ratio 3,605 ve trombosit odds ratio 0,995 anormal toraks tomografisi ile ilişkili olduğu saptanmıştır. Sonuç: Bu çalışma, Türkiye'nin Doğu Karadeniz Bölgesi'ndeki COVID19 enfeksiyonu olan hastaların klinik özelliklerin önemini gösteren temel veriler sunmaktadır. Bulgular, gelecekteki araştırmalarda bir bilgi tabanı olarak ve hastalar arasında güvenlik algılarını iyileştirmeye yönelik prosedürleri uygulamak için kullanılabilir.
Anahtar Kelimeler: COVID-19; SARS-CoV-2; Türkiye; klinik özellikler; salgın
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