Objective: People with rheumatoid arthritis (RA) often experience fatigue. However, most of these individuals are not assessed for fatigue. The purpose of this study was to examine the relationship between functional status, pain, disease activity, and fatigue in people with RA. Material and Methods: 141 individuals with RA participated in this study. Patients' pain intensity was assessed using the visual analog scale (VAS). The Health Assessment Questionnaire (HAQ) was used to determine functional status. The scale for assessing the disease activity of the participants was the Disease Activity Score-28 (DAS28). To assess fatigue, the Fatigue Symptom Inventory (FSI) was used. Results: Duration scores (amount of time felt tired, number of days felt tired), interference score and severity scores (current, mean, minimum, maximum) of FSI had statistically significant relationships with the number of tender and swollen joints, HAQ, DAS-28, VAS motion and rest scores (p<0.05). FSI scores were not associated with duration or age. The HAQ score was a statistically significant predictor of high clinical fatigue in logistic regression analysis. Conclusion: Fatigue was found to affect patients with RA independently of disease duration. Fatigue was associated with functional status, pain, and disease activity. The findings suggest that functional status independently associated with clinical fatigue. Fatigue should be considered as a considerable symptom in the clinical assessment of patients and associated factors should be addressed.
Keywords: Fatigue; rheumatoid arthritis; pain
Amaç: Romatoid artritli (RA) hastalarda yorgunluk yaygın olarak görülen bir semptomdur ancak bu hastaların çoğu yorgunluk açısından değerlendirilmemektedir. Bu çalışmada, RA'lı hastalarda yorgunluk ile fonksiyonel durum, hastalık aktivitesi ve ağrı arasındaki ilişkiyi belirlemek amaçlanmıştır. Gereç ve Yöntemler: Çalışmaya toplam 141 RA'lı hasta dâhil edilmiştir. Hastalarda görsel analog skala [visual analog scale (VAS)] kullanılarak ağrının şiddeti değerlendirilmiştir. Katılımcıların fonksiyonel durumları Sağlık Değerlendirme Anketi [Health Assessment Questionnaire (HAQ)], hastalık aktiviteleri ise Hastalık Aktivite Skoru-28 [Disease Activity Score-28 (DAS-28)] ile belirlenmiştir. Yorgunluğu değerlendirmek için Yorgunluk Semptom Envanteri [Fatigue Symptom Inventory (FSI)] kullanılmıştır. Bulgular: İstatistiksel olarak FSI süre skorları (yorgun hissedilen süre, yorgun hissedilen gün sayısı), interferans skoru, şiddet skorları (mevcut, ortalama, minimum, maksimum) ile şiş ve hassas eklem sayısı, HAQ, DAS-28, VAS skorları arasında bir ilişki mevcuttu (p<0,05). Hastalık süresi ve yaş ile FSI skorları arasında istatistiksel olarak bir ilişki görülmemiştir. Lojistik regresyon analizi, HAQ skorunun yüksek klinik yorgunluğun istatistiksel olarak anlamlı bir belirleyicisi olduğunu göstermiştir. Sonuç: Hastalık süresinden bağımsız olarak RA'lı hastalarda yorgunluk hastaları etkilemektedir. Yorgunluk RA'lı hastalarda ağrı, fonksiyonel durum ve hastalık aktivitesi ile ilişkilidir. Bulgular RA'lı hastalarda fonksiyonel durum ile klinik yorgunluğun bağımsız olarak ilişkili olduğunu göstermektedir. Yorgunluk RA'lı hastaların klinik değerlendirmesinde önemli bir semptom olarak göz önünde bulundurulmalı ve ilişkili faktörler ele alınmalıdır.
Anahtar Kelimeler: Yorgunluk; romatoid artrit; ağrı
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