.: ORİJİNAL ARAŞTIRMA
Evaluation of Demographic and Hematologic Parameters in Nephrolithiasis Patients with and without Prostate Stones: Cross-sectional Study
Prostat Taşı Olan ve Olmayan Böbrek Taşlı Olgularda Demografik ve Hematolojik Parametrelerin Değerlendirilmesi: Kesitsel Çalışma
Turkiye Klinikleri J Med Sci. 2021;41(3):214-8
doi: 10.5336/medsci.2020-78637
Makale Dili: EN
Tam Metin
ABSTRACT
Objective: Prostate stones are regarded as asymptomatic and clinically insignificant and ignored by clinicians.To investigate the clinical and demographic differences between patients with and without prostate stones. Material and Methods: Since similar etiological factors play a role in the formation of prostate stones and kidney stones, male patients with clinically important kidney stones were retrospectively analyzed and grouped as patients with and without prostate stones. The presence of prostate calculi was detected with abdominopelvic non-contrast computerized tomography. A total of 244 patients were included in the study (144 [59.02%] had no prostate stone, 100 [40.98%] had prostate stones). The demographic and clinical data (age, urine pH, urine density, leukocyte count, neutrophil count, lymphocyte count, thrombocyte count, mean thrombocyte volume (MPV), neutrophil-lymphocyte ratio (NLR), thrombocyte lymphocyte ratio (PLR), kidney stone volume, kidney stone Hounsfield unit (HU), abdominal anterior wall fat thickness) were analyzed between those with and without prostate stones. Results: Demographic and clinical data analysis between patients with and without prostate stones obtained statistical results for age (p=0.000), urine pH (p=0.479), urine density (p=0.215), leukocyte count (p=0.168), neutrophil count (p=0.055), lymphocyte count (p=0.712), platelet count (p=0.589), mean platelet volume (p=0.682), NLR (p=0.045), PLR (p=0.902), stone volume (p=0.307), HU (p=0.117), and anterior abdominal fat thickness (p=0.751). Conclusion: Advanced age and high NLR can be considered risk factors for prostate stone formation.
Keywords: Prostate stone; nephrolithiasis; inflammation; neutrophil
Objective: Prostate stones are regarded as asymptomatic and clinically insignificant and ignored by clinicians.To investigate the clinical and demographic differences between patients with and without prostate stones. Material and Methods: Since similar etiological factors play a role in the formation of prostate stones and kidney stones, male patients with clinically important kidney stones were retrospectively analyzed and grouped as patients with and without prostate stones. The presence of prostate calculi was detected with abdominopelvic non-contrast computerized tomography. A total of 244 patients were included in the study (144 [59.02%] had no prostate stone, 100 [40.98%] had prostate stones). The demographic and clinical data (age, urine pH, urine density, leukocyte count, neutrophil count, lymphocyte count, thrombocyte count, mean thrombocyte volume (MPV), neutrophil-lymphocyte ratio (NLR), thrombocyte lymphocyte ratio (PLR), kidney stone volume, kidney stone Hounsfield unit (HU), abdominal anterior wall fat thickness) were analyzed between those with and without prostate stones. Results: Demographic and clinical data analysis between patients with and without prostate stones obtained statistical results for age (p=0.000), urine pH (p=0.479), urine density (p=0.215), leukocyte count (p=0.168), neutrophil count (p=0.055), lymphocyte count (p=0.712), platelet count (p=0.589), mean platelet volume (p=0.682), NLR (p=0.045), PLR (p=0.902), stone volume (p=0.307), HU (p=0.117), and anterior abdominal fat thickness (p=0.751). Conclusion: Advanced age and high NLR can be considered risk factors for prostate stone formation.
Keywords: Prostate stone; nephrolithiasis; inflammation; neutrophil
ÖZET
Amaç: Prostat taşları asemptomatik ve klinik önemsiz olarak kabul edilerek klinisyenler tarafından göz ardı edilmektedirler. Prostat taşı olan hastalarla olmayanlar arasındaki demografik ve hematolojik parametereleri incelemeyi amaçladık. Gereç ve Yöntemler: Prostat ve böbrek taşı oluşumunda benzer etiyolojik faktörler rol oynadığından dolayı klinik önemli böbrek taşı olan erkek hastalar retrospektif olarak incelendi ve prostat taşı olan hastalar ile olmayanlar diye gruplandırıldı. Hastaların prostat taşı mevcudiyeti ince kesit abdominopelvik bilgisarlı tomografi ile değerlendirildi. Toplam 244 (144 [%59.02] hastada prostat taşı yok, 100 [%40.98] hastada prostat taşı var) hasta çalışmaya alındı. Olguların demografik ve klinik verileri (yaş, idrar pH'si ve dansitesi, lökosit, nötrofil, lenfosit ve trombosist sayısı, ortalama trombosit hacmi (MPV), nötrofil lenfosit (NLR) ve trombosit lenfosit oranları (PLR), böbrek taş hacmi, böbrek taş Hounsfield ünitesi (HU), karın ön duvar yağ kalınlığı) analiz edildi. Bulgular: Prostat taşı olan ve olmayan hastalar arasındaki demografik ve klinik veri analizinde sadece yaşın ve NLR'nin gruplar arasında fark ettiği görüldü (p=0.000 ve p=0,045). İdrar pH'si (p=0,479), idrar yoğunluğu (p=0,215), lökosit (p=0,168), nötrofil (p=0,055), lenfosit (p=0,712) ve trombosit sayısı (p=0,589), MPV (p=0,682), PLR (p=0,902), böbrek taş hacmi (p=0,307), HU (p=0,117) ve karın ön duvar yağ kalınlığı (p=0,751) gruplar arasında farklı bulunmadı. Sonuç: İleri yaş ve yüksek NLR prostat oluşumu için risk faktörü olarak değerlendirilebilir.
Anahtar Kelimeler: Prostat taşı; nefrolitiyazis; inflamasyon; nötrofil
Amaç: Prostat taşları asemptomatik ve klinik önemsiz olarak kabul edilerek klinisyenler tarafından göz ardı edilmektedirler. Prostat taşı olan hastalarla olmayanlar arasındaki demografik ve hematolojik parametereleri incelemeyi amaçladık. Gereç ve Yöntemler: Prostat ve böbrek taşı oluşumunda benzer etiyolojik faktörler rol oynadığından dolayı klinik önemli böbrek taşı olan erkek hastalar retrospektif olarak incelendi ve prostat taşı olan hastalar ile olmayanlar diye gruplandırıldı. Hastaların prostat taşı mevcudiyeti ince kesit abdominopelvik bilgisarlı tomografi ile değerlendirildi. Toplam 244 (144 [%59.02] hastada prostat taşı yok, 100 [%40.98] hastada prostat taşı var) hasta çalışmaya alındı. Olguların demografik ve klinik verileri (yaş, idrar pH'si ve dansitesi, lökosit, nötrofil, lenfosit ve trombosist sayısı, ortalama trombosit hacmi (MPV), nötrofil lenfosit (NLR) ve trombosit lenfosit oranları (PLR), böbrek taş hacmi, böbrek taş Hounsfield ünitesi (HU), karın ön duvar yağ kalınlığı) analiz edildi. Bulgular: Prostat taşı olan ve olmayan hastalar arasındaki demografik ve klinik veri analizinde sadece yaşın ve NLR'nin gruplar arasında fark ettiği görüldü (p=0.000 ve p=0,045). İdrar pH'si (p=0,479), idrar yoğunluğu (p=0,215), lökosit (p=0,168), nötrofil (p=0,055), lenfosit (p=0,712) ve trombosit sayısı (p=0,589), MPV (p=0,682), PLR (p=0,902), böbrek taş hacmi (p=0,307), HU (p=0,117) ve karın ön duvar yağ kalınlığı (p=0,751) gruplar arasında farklı bulunmadı. Sonuç: İleri yaş ve yüksek NLR prostat oluşumu için risk faktörü olarak değerlendirilebilir.
Anahtar Kelimeler: Prostat taşı; nefrolitiyazis; inflamasyon; nötrofil
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