Amaç: İnternal üretrotomi, üroloji kliniklerinde en sık yapılan cerrahi uygulamalarından biridir. Çalışmanın amacı, çeşitli sebeplerle anterior üretra darlığı gelişen hastalarda erken üretral kateter dilatasyonunun (yumuşak self kateter) nüks üzerine etkisinin araştırılmasıdır. Gereç ve Yöntemler: Kliniğimizde soğuk bıçak yöntemiyle internal üretrotomi yapılan 42 hasta, dilatasyon uygulanan zamana göre gruplandırıldı; üçüncü ay sonunda üroflowmetri sonucuyla değerlendirilip gruplar arasındaki fark karşılaştırıldı. Dilatasyonun ilk uygulama zamanı postoperatif beşinci gün olan ve altı kez/aylık toplam 18 kez dilatasyon yapılan 1. grup 16 hasta, uygulama zamanı postoperatif 15. gün olan iki kez/aylık toplam altı kez dilatasyon yapılan 2. grup 13 hasta ve dilatasyon uygulanmayan 3. grup 13 hasta olmak üzere toplam 42 hasta çalışmaya dâhil edildi. Üçüncü ay sonunda üroflowmetri ile değerlendirilen hastalar erken nüks oranları açısından karşılaştırıldı. Bulgular: Erken dilatasyon uygulanan, anterior üretra darlıklı 1. gruptaki hastalarla geç başlangıçlı dilatasyon uygulanan 2. gruptaki hastalar arasında nüks açısından istatistiksel olarak anlamlı fark saptanmadı. Dilatasyon uygulanmayan 3. grupta, 1. gruba göre nüks lehine istatistiksel olarak anlamlı bir fark saptandı. Dilatasyon uygulanan 1 ve 2. gruplar dilatasyon uygulanmayan 3. grupla karşılaştırıldığında sınırda anlamlı fark saptanırken, 2. grup ile 3. grubun kıyaslamasında istatistiksel olarak anlamlı fark bulunmadı. Sonuç: İnternal üretrotomi sonrası sık tekrarlayan nüks en büyük sorundur. Bu nedenle uygulanan mükerrer internal üretrotomiler hem başarı açısından düşük yüzdelere sahiptir hem de bu yaklaşım, daha sonra uygulanacak üretroplastinin başarı şansını azaltmaktadır. Postoperatif erken dilatasyon ile bu endoskopik yöntemin başarı oranının artırılabileceği ve mükerrer üretral darlıkların önüne geçilebileceği düşünülmektedir.
Anahtar Kelimeler: İnternal üretrotomi; erken dilatasyon; nüks
Objective: Internal urethrotomy is one of the most frequently performed surgeries in urology clinics. The aim of this study was to investigate the effect of early urethral catheter dilatation (soft self-catheter) on recurrence in patients with anterior urethral stricture. Material and Methods: The patients who underwent internal urethrotomy with cold knife method were grouped according to the time of dilatation and evaluated by uroflowmetry at the end of the third month. A total of 42 patients were included in the study. The patients who underwent first dilatation at the 5th day after the operation, with a total number of 18 dilatations (16 patients), were included in the first group. The patients who underwent first dilatation at the 15th day after the operation, with a total number of 6 dilatations (13 patients), were included in the second group. The patients who did not undergo dilatation were included in the third group (13 patients). Patients were compared in terms of early recurrence rates with uroflowmetry at the end of the third month. Results: There was no statistically significant difference between the first and second group of patients in terms of recurrence in ureteral stricture. However, there was a statistically significant difference in terms of relapse in urethral stricture between the first group and the third group who had not gone dilatation. There was no statistically significant difference between the second and third groups. When compared in terms of the same variable. Conclusion: Recurrent strictures after internal urethrotomy is the most challenging problem. Repeated internal urethrotomy have low success rates and also decrease the success rate of urethroplasty. We suggest that the success rate of the endoscopic method can be increased by postoperative early dilatation and by this approach, repeated urethral strictures can be prevented.
Keywords: Internal urethrotomy; early dilatation; recurrence
- Mundy AR, Andrich DE. Urethral strictures. BJU Int. 2011;107(1):6-26. [Crossref] [PubMed]
- Jordan GH, McCammon KA. Surgery of the penis and urethra. In: Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA, eds. Campbell-Walsh Urology. 10th ed. Philadelphia: WB Saunders; 2012. p.956-1000. [Crossref]
- Rasswailer J, Teber D, Kuntz R, Hofmann R. Complications of transurethral resection of the prostate (TURP)--incidence, management and prevention. Eur Urol. 2006;50(5):969-79. [Crossref] [PubMed]
- Varkarakis I, Kyriakakis Z, Delis A, Protogerou V, Deliveliotis C. Long-term results of open transvesical prostatectomy from a contemporary series of patients. Urology. 2004;64(2): 306-10. [Crossref] [PubMed]
- Altinova S, Serefoglu EC, Ozdemir AT, Atmaca AF, Akbulut Z, Balbay MD. Factors affecting urethral stricture development after radical retropubic prostatectomy. Int Urol Nephrol. 2009;41(4):881-4. [Crossref] [PubMed]
- Moltzahn F, Dal Pra A, Furrer M, Thalmann G, Spahn M. Urethral stricture after radiation therapy for prostate cancer. Investig Clin Urol. 2016;57(5):309-15. [Crossref] [PubMed] [PMC]
- Sachse H. [Cystoscopic transurethral incision of urethral stricture with a sharp instrument (author?s transl)]. MMW Munch Med Wochenschr. 1974;116(49):2147-50.
- Tonkin JB, Jordan GH. Management of distal anterior urethral strictures. Nat Rev Urol. 2009;6(10):533-8. [Crossref] [PubMed]
- Veeratterapillay R, Pickard RS. Long-term effect of urethral dilatation and internal urethrotomy for urethral strictures. Curr Opin Urol. 2012;22(6):467-73. [Crossref] [PubMed]
- Albers P, Fictner J, Brühl P, Müller SC. Longterm results of internal urethrotomy. J Urol. 1996;156(5):1611-4. [Crossref] [PubMed]
- Lawrence WT, MacDonagh RP. Treatment of urethral stricture disease by internal urethrotomy followed by intermittent ?low-friction? selfcatheterization: preliminary communication. J R Soc Med. 1988;81(3):136-9. [Crossref]
- Harriss DR, Beckingham IJ, Lemberger RJ, Lawrence WT. Long-term results of intermittent low-friction self-catheterization in patients with recurrent urethral strictures. Br J Urol. 1994;74(6):790-2. [Crossref] [PubMed]
- Robertson GS, Everitt N, Lamprecht JR, Brett M, Flynn JT. Treatment of recurrent urethral strictures using clean intermittent selfcatheterisation. Br J Urol. 1991;68(1):89-92.[Crossref] [PubMed]
- Wessells H, Angermeier KW, Elliot SP, Gonzalez CM, Kodama RT, Peterson AC, et al. Male Urethral Stricture: AUA Guideline 2016. [Link]
- Baskin LS, Constantinescu SC, Howard PS, McAninch JW, Ewalt DH, Duckett JW, et al. Biochemical characterization and quantitation of the collagenous components of urethral stricture tissue. J Urol. 1993;150(2 Pt 2):642-7. [Crossref]
- Lauritzen M, Greis G, Sandberg A, Wedren H, Ojdeby G, Henningsohn L. Intermittent self-dilatation after internal urethrotomy for primary urethral strictures: a case-control study. Scand J Urol Nephrol. 2009;43(3):220-5. [Crossref] [PubMed]
- Matanhelia SS, Salaman R, John A, Matthews PN. A prospective randomized study of self dilatation in the management of urethral strictures. J R Coll Surg Edinb. 1995;40(5):2957.
- Bødker A, Ostri P, Rye-Andersen J, Edvardsen L, Struckmann J. Treatment of recurrent urethral stricture by internal urethrotomy and intermittent self-catheterization: a controlled study of a new therapy. J Urol. 1992;148(2 Pt 1):308-10. [Crossref]
- Tammela TL, Permi J, Ruutu M, Talja M. Clean intermittent self-catheterization after urethrotomy for recurrent urethral strictures. Ann Chir Gynaecol Suppl. 1993;206:80-3.
- Kjaergaard B, Walter S, Bartholin J, Andersen JT, Nøhr S, Beck H, et al. Prevention of urethral stricture recurrence using clean intermittent self-catheterization. Br J Urol. 1994;73(6):692-5. [Crossref] [PubMed]
- Pansadoro V, Emiliozzi P. Internal urethrotomy in the management of anterior urethral strictures: long-term followup. J Urol. 1996;156(1):73-5. [Crossref] [PubMed]
- Steenkamp JW, Heyns CF, de Kock ML. Internal urethrotomy versus dilation as treatment for male urethral strictures: a prospective, randomized comparison. J Urol. 1997;157(1):98-101. [Crossref]
- Mangera A, Osman N, Chapple C. Evaluation and management of anterior urethral stricture disease. F1000Res. 2016;5:153. [Crossref] [PubMed] [PMC]
- Ivaz SL, Veeratterapillay R, Jackson MJ, Harding CK, Dorkin TJ, Andrich DE, et al. Intermittent self-dilatation for urethral stricture disease in males: a systematic review and meta-analysis. Neurourol Urodyn. 2016;35(7): 759-63. [Crossref] [PubMed]
- Maciejewski C, Rourke K. Imaging of urethral stricture disease. Transl Androl Urol. 2015;4(1):2-9.
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