Objective: Vitamins and minerals, micronutrients, play a role in the cellular structure of the normal hair follicle cycle, essential for the growth and function of matrix cells in the hair follicle. They can cause hair loss when they are insufficient. We aimed to investigate the potential role of deficiencies of micronutrients in the etiology of male hair loss. Material and Methods: A total of 116 male patients aged 18-30 years, who were admitted between November 2018 and October 2019, were included in the study. Male patients with a diagnosis of androgenetic alopecia (AGA) and telogen effluvium (TE) were included. The factors that may play a role in the etiology, were investigated with the following tests; hemogram, fasting blood glucose, serum iron, ferritin, folate, vitamin B12 and D levels, zinc levels and thyroid function tests. Results: The mean age of the patients with TE was 23.18±3.6 years, and the mean age of the patients with AGA was 24.43±3.59 years. AGA was found to be 62.06% and TE was found to be 37.93% in the study group. In general, the deficiencies of vitamin D, vitamin B12 and low ferritin levels were found as 54.3 (n=63), 45.6 (n=53) and 15.5% (n=18) respectively. The mean time of hair loss was 37.7±35 months. Family history was positive 69.44% (n=50) in AGA, 45.5% (n=20) in TE. Conclusion: Especially vitamins D and B12 levels were found to be lower. Therefore, we recommend that these tests should be requested in male patients with hair loss and we think this will contribute to the treatment.
Keywords: Androjenik alopesi; saç dökülmesi; erkekler; mikrobesinler; telogen effluvium
Amaç: Vitaminler ve mineraller, yani mikro besinler, normal saç folikülü döngüsünde hücresel yapıda rol oynarlar, kıl folikülünde matriks hücrelerinin büyümesi ve işlevi için gereklidir. Yetersiz olduklarında saç dökülmesine neden olabilirler. Bu çalışmada, saç dökülmesi ve seyrelmesi ile başvuran erkek hastalarda etiyolojinin olası rolünü araştırmayı amaçladık. Gereç ve Yöntemler: Kasım 2018 ile Ekim 2019 arasında saç dökülmesi şikâyeti ile başvuran toplam 116 hasta çalışmaya alındı. Androgenetik alopesi (AGA) ve telogen effluvium (TE) tanısı alan 18-30 yaş arası genç yetişkin erkekler araştırmaya dâhil edildi. Hemogram, açlık kan şekeri, serum demir, ferritin, folat, vitamin B12 ve D düzeyleri, çinko düzeyleri ve tiroid fonksiyon testleri incelenerek etiyolojide rol oynayabilen faktörler araştırıldı. Bulgular: TE'li hastaların ortalama yaşı 23,18±3,6 yıl, AGA'lı hastaların ortalama yaşı 24,43±3,59 yıldı. Hastaların %62,06'sında AGA, %37,93'ünde TE saptandı. Tüm hastalarda D vitamini eksikliği %54,3 (n=63), B12 vitamini eksikliği %45,6 (n=53), ferritin değerinde düşüklük %15,5 (n=18) olarak bulundu. Saç dökülmesinin ortalama süresi 37,7±35 aydı. Aile öyküsü AGA'da %69,44 (n=50), TE'de %45,5 (n=20) pozitif idi. Sonuç: Çalışmamızda özellikle vitamin D ve B12 düzeyleri daha düşük bulundu. Bu nedenle saç dökülmesi olan erkek hastalarda bu testlerin istenmesini öneriyoruz, bunun tedaviye de katkıda bulunacağını düşünüyoruz.
Anahtar Kelimeler: Androgenic alopecia; hair loss; men; micronutrients; telogen effluvium
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