Turkiye Klinikleri Journal of Dental Sciences

.: ORIGINAL RESEARCH
The Investigation of Osteoporotic Changes in Patients with Primary Hyperparathyroidism with Radiomorphometric Indices Determined on Panoramic Radiography
Primer Hiperparatiroidili Hastalardaki Osteoporotik Değişikliklerin Panoramik Radyografide Belirlenen Radyomorfometrik İndeksler ile İncelenmesi
Özkan MİLOĞLUa, Furkan CANTÜRKa, Gülsüm AKKAYAa, Arzu BİLENb
aDepartment of Oral and Maxillofacial Radiology, Atatürk University Faculty of Dentistry, Erzurum, TURKEY
bDepartment of Endocrinology, Atatürk University Faculty of Medicine, Erzurum, TURKEY
Turkiye Klinikleri J Dental Sci. 2021;27(4):586-93
doi: 10.5336/dentalsci.2021-81152
Article Language: EN
Full Text
ABSTRACT
 Objective: The aim of this study was to compare osteoporotic changes of jaw bones between normal population and patients with primary hyperparathyroidism (pHPT) by using panoramic radiomorphometric analyses. Material and Methods: Panoramic radiographs of 48 healthy individuals and 48 patients with pHPT were evaluated. The values of the panoramic mandibular index (PMI), mental index (MI) mandibular cortical width (MCW), amount of alveolar bone resorption (AABR) were measured. Mandibular cortical index (MCI) was recorded on panoramic radiographs according to C1, C2 and C3 classes with increased trabecular structure of the cortical bone. In panoramic radiographs, carotid artery calcification was examined. Results: There was no statistically significant difference between the patient group and the control group for PMI, MI, MCW and AABR values from radiomorphometric measurements. While there was a significant difference between categories C1 and C3 of MCI values between patient and control group; there was no significant difference for category C2 values. Unilateral carotid artery calcification was observed on panoramic radiography of 5 individuals in the patient group. Conclusion: Osteoporotic changes were not observed in patients with pHPT as compared with control group by using radiomorphometric analysis, while mandibular cortical destruction was observed in pHPT patient group.

Keywords: Primary hyperparathyroidism; cortical bone; radiomorphometry; panoramic radiography
ÖZET
 Amaç: Bu çalışma, primer hiperparatiroidili (pHPT) hastalardaki çene kemiğine ait osteoporotik değişikliklerin, panoramik radyografi kullanılarak belirlenen radyomorfometrik indeksler ile değerlendirilmesini amaçlamıştır. Gereç ve Yöntemler: pHPT tanısı alan 48 birey ile kontrol grubunu oluşturan sağlıklı 48 bireyin panoramik radyografileri üzerinde; panoramik mandibular indeks (PMI), mental indeks (MI), mandibular kortikal kalınlık (MKK), alveoler kemik rezorpsiyon miktarı (AKRM) ölçüldü. Mandibular kortikal indeks (MKI) panoramik radyografiler üzerinde, kortikal kemiğin artmış trabeküler yapısının C1, C2 ve C3 sınıflarından uyumlu görünüm sergilediği sınıfa göre kaydedildi. Panoramik radyografide, karotid arter kalsifikasyonu varlığı araştırıldı. Bulgular: Radyomorfometrik ölçümlerden PMI, MI, MKK ve AKRM değerleri için hasta grubu ile kontrol grubu arasında istatistiksel olarak anlamlı fark bulunmadı. Hasta grubu ile kontrol grubu arasında MKI sınıflandırmalarından C1 ve C3 sınıf değerleri arasında anlamlı bir fark var iken; C2 sınıf değerleri arasında anlamlı bir fark bulunmamıştır. Hasta grubundaki, 5 bireyin panoramik radyografisinde unilateral karotid arter kalsifikasyonu izlendi. Sonuç: Radyomorfometrik analizler ile pHPT hastalarında kontrol grubuna kıyasla anlamlı osteoporotik değişiklikler izlenmemiş olmakla birlikte pHPT'li hastalarda, mandibular kortikal destrüksiyon tespit edilmiştir.

Anahtar Kelimeler: Primer hiperparatiroidi; kortikal kemik; radyomorfometri; panoramik radyografi
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