Turkiye Klinikleri Journal of Dental Sciences

.: ORIGINAL RESEARCH
The Impact of Intracanal Heating and Irrigation Solution Activation on Organic Tissue Removal from Internal Resorption Cavities: An in vitro Study
İnternal Rezorpsiyon Kavitesinden Organik Doku Uzaklaştırılmasına İntrakanal Isıtma ve İrrigasyon Solüsyonu Aktivasyonunun Etkisi: in vitro Çalışma
Öznur SARIYILMAZa , Emek BAYINDIRa , Evren SARIYILMAZa , Kardelen YILDIRIMb , Mahmut Can TOKAŞb
aÇanakkale Onsekiz Mart University Faculty of Dentistry, Department of Endodontics, Çanakkale, Türkiye
bÇanakkale Onsekiz Mart University Faculty of Dentistry, Çanakkale, Türkiye
Turkiye Klinikleri J Dental Sci. 2025;31(1):59-66
doi: 10.5336/dentalsci.2024-105761
Article Language: EN
Full Text
ABSTRACT
 Objective: This study aimed to compare various activation techniques for removing organic tissue from simulated internal resorption cavities, utilizing sodium hypochlorite (NaOCl) at both intracanal heated and room temperature. Material and Methods: A total of 120 mandibular premolar teeth were horizontally divided into two parts, and internal resorption cavities were created in each part. Bovine muscle tissue samples were inserted into resorption cavities. Roots were reassembled, and teeth divided into two groups (n=60) by irrigation temperature (room temperature, intracanal heated). Each of the two groups was further divided into 5 subgroups for irrigation activation purposes: standard needle irrigation (SNI), EndoActivator (EA), EDDY, passive ultrasonic irrigation, XP-endo Finisher (XPF). After irrigation protocols, organic tissue remnants in resorption cavities were scored and differences among tissue removal scores were analyzed. Results: XPF demonstrated superior organic tissue removal compared to SNI in both room temperature and intracanal heated NaOCl groups. All activation groups showed no significant difference in the efficacy of organic tissue removal between NaOCl at room temperature and when heated intracanal. Conclusion: The XPF was found to be the most effective method for removing organic tissue from internal resorption cavities. Intracanal heating NaOCl did not have any significant effect on removing organic tissue from internal resorption cavities.

Keywords: Sodium hypochlorite; root canal irrigants; root resorption
ÖZET
 Amaç: Bu çalışma ile simüle edilmiş internal rezorpsiyon kavitelerinden organik dokunun uzaklaştırılması için hem kanal içinde ısıtılan hem de oda sıcaklığındaki sodyum hipoklorite (NaOCl) uygulanan aktivasyon tekniklerinin karşılaştırılması amaçlanmıştır. Gereç ve Yöntemler: Toplamda 120 mandibular premolar diş yatay olarak 2 parçaya bölünmüş ve her parçaya internal rezorpsiyon kaviteleri oluşturulmuştur. Rezorpsiyon kavitelerine sığır kas dokusu yerleştirilmiş ve kökler tekrar birleştirilmiştir. Dişler, irrigasyon sıcaklığına göre 2 gruba (n=60) ayrılmıştır (oda sıcaklığı, intrakanal ısıtma). Her iki grup, irrigasyon aktivasyon yöntemlerine göre 5 alt gruba ayrılmıştır: standart iğne irrigasyonu [standard needle irrigation (SNI)], EndoActivator (EA), EDDY, pasif ultrasonik irrigasyon, XP-endo Finisher (XPF). İrrigasyon protokollerinden sonra rezorpsiyon kavitelerinde kalan organik doku kalıntıları değerlendirilmiş ve doku uzaklaştırma skorları arasındaki farklar analiz edilmiştir. Bulgular: XPF hem oda sıcaklığındaki hem de intrakanal ısıtılmış NaOCl gruplarında SNI'ya kıyasla daha üstün organik doku uzaklaştırma performansı göstermiştir. Tüm aktivasyon gruplarında, NaOCl'nin oda sıcaklığı ve intrakanal ısıtma arasındaki organik doku uzaklaştırma etkinliği açısından anlamlı bir fark bulunmamıştır. Sonuç: XPF internal rezorpsiyon kavitelerinden organik doku uzaklaştırmada en etkili yöntem olarak bulunmuştur. NaOCl'nin kanal içi ısıtılmasının internal rezorpsiyon kavitesinden organik doku uzaklaştırılması üzerinde önemli bir etkisi olmamıştır.

Anahtar Kelimeler: Sodyum hipoklorit; kök kanalı sulayıcıları; kök rezorpsiyonu
REFERENCES:
  1. Patel S, Ricucci D, Durak C, Tay F. Internal root resorption: a review. J Endod. 2010;36(7):1107-21. [Crossref]  [PubMed] 
  2. Lyroudia KM, Dourou VI, Pantelidou OC, Labrianidis T, Pitas IK. Internal root resorption studied by radiography, stereomicroscope, scanning electron microscope and computerized 3D reconstructive method. Dent Traumatol. 2002;18(3):148-52. [Crossref]  [PubMed] 
  3. Whitten BH, Gardiner DL, Jeansonne BG, Lemon RR. Current trends in endodontic treatment: report of a national survey. J Am Dent Assoc. 1996;127(9):1333-41. [Crossref]  [PubMed] 
  4. Haapasalo M, Shen Y, Wang Z, Gao Y. Irrigation in endodontics. Br Dent J. 2014;216(6):299-303. [Crossref]  [PubMed] 
  5. Neelakantan P, Cheng CQ, Mohanraj R, Sriraman P, Subbarao C, Sharma S. Antibiofilm activity of three irrigation protocols activated by ultrasonic, diode laser or Er:YAG laser in vitro. Int Endod J. 2015;48(6):602-10. [Crossref]  [PubMed] 
  6. Ulusoy ÖI, Savur IG, Alaçam T, Çelik B. The effectiveness of various irrigation protocols on organic tissue removal from simulated internal resorption defects. Int Endod J. 2018;51(9):1030-6. [Crossref]  [PubMed] 
  7. Estevez R, Conde AJ, Valencia de Pablo O, de la Torre F, Rossi-Fedele G, Cisneros R. Effect of passive ultrasonic activation on organic tissue dissolution from simulated grooves in root canals using sodium hypochlorite with or without surfactants and EDTA. J Endod. 2017;43(7):1161-5. [Crossref]  [PubMed] 
  8. Guneser MB, Arslan D, Usumez A. Tissue dissolution ability of sodium hypochlorite activated by photon-initiated photoacoustic streaming technique. J Endod. 2015;41(5):729-32. [Crossref]  [PubMed] 
  9. Sirtes G, Waltimo T, Schaetzle M, Zehnder M. The effects of temperature on sodium hypochlorite short-term stability, pulp dissolution capacity, and antimicrobial efficacy. J Endod. 2005;31(9):669-71. [Crossref]  [PubMed] 
  10. Rossi-Fedele G, De Figueiredo JA. Use of a bottle warmer to increase 4% sodium hypochlorite tissue dissolution ability on bovine pulp. Aust Endod J. 2008;34(1):39-42. [Crossref]  [PubMed] 
  11. Cunningham WT, Balekjian AY. Effect of temperature on collagen-dissolving ability of sodium hypochlorite endodontic irrigant. Oral Surg Oral Med Oral Pathol. 1980;49(2):175-7. [Crossref]  [PubMed] 
  12. Cunningham WT, Joseph SW. Effect of temperature on the bactericidal action of sodium hypochlorite endodontic irrigant. Oral Surg Oral Med Oral Pathol. 1980;50(6):569-71. [Crossref]  [PubMed] 
  13. Berutti E, Marini R. A scanning electron microscopic evaluation of the debridement capability of sodium hypochlorite at different temperatures. J Endod. 1996;22(9):467-70. [Crossref]  [PubMed] 
  14. Yared G, Al Asmar Ramli G. Antibacterial ability of sodium hypochlorite heated in the canals of ınfected teeth: an ex vivo study. Cureus. 2020;12(2):e6975. [Crossref]  [PubMed]  [PMC] 
  15. Iandolo A, Abdellatif D, Amato M, Pantaleo G, Blasi A, Franco V, et al. Dentinal tubule penetration and root canal cleanliness following ultrasonic activation of intracanal-heated sodium hypochlorite. Aust Endod J. 2020;46(2):204-9. [Crossref]  [PubMed] 
  16. Leonardi DP, Grande NM, Tomazinho FSF, Marques-da-Silva B, Gonzaga CC, Baratto-Filho F, et al. Influence of activation mode and preheating on intracanal irrigant temperature. Aust Endod J. 2019;45(3):373-7. [Crossref]  [PubMed] 
  17. de Hemptinne F, Slaus G, Vandendael M, Jacquet W, De Moor RJ, Bottenberg P. In vivo ıntracanal temperature evolution during endodontic treatment after the ınjection of room temperature or preheated sodium hypochlorite. J Endod. 2015;41(7):1112-5. [Crossref]  [PubMed] 
  18. Macedo RG, Verhaagen B, Versluis M, van der Sluis L. Temperature evolution of preheated irrigant injected into a root canal ex vivo. Clin Oral Investig. 2017;21(9):2841-50. [Crossref]  [PubMed] 
  19. Jain S, Patni PM, Jain P, Raghuwanshi S, Pandey SH, Tripathi S, et al. Comparison of dentinal tubular penetration of ıntracanal heated and preheated sodium hypochlorite through different agitation techniques. J Endod. 2023;49(6):686-91. [Crossref]  [PubMed] 
  20. Rathore V, Samel D, Moogi P, Bandekar S, Kshirsagar S, Vyas C. Antimicrobial efficacy of intracanal and extracanal heated sodium hypochlorite against enterococcus faecalis: an in vitro study. Endodontology. 2020;32(3):112-7. [Crossref] 
  21. Ruddle CJ. Endodontic disinfection: Tsunami irrigation. Saudi Endod J. 2015;5(1):1-12. [Crossref] 
  22. Raducka M, Piszko A, Piszko PJ, Jawor N, Dobrzyński M, Grzebieluch W, Mikulewicz M, Skośkiewicz-Malinowska K. Narrative Review on Methods of Activating Irrigation Liquids for Root Canal Treatment. Appl Sci. 2023; 13(13):7733. [Crossref] 
  23. Gomes BPFA, Aveiro E, Kishen A. Irrigants and irrigation activation systems in endodontics. Braz Dent J. 2023;34(4):1-33. [Crossref]  [PubMed]  [PMC] 
  24. Lauritano D, Moreo G, Carinci F, Della Vella F, Di Spirito F, Sbordone L, Petruzzi M. Cleaning Efficacy of the XP-Endo® Finisher Instrument Compared to Other Irrigation Activation Procedures: A Systematic Review. Appl Sci. 2019;9(23):5001. [Crossref] 
  25. Abu Hasna A, Monteiro JB, Abreu RT, Camillo W, Nogueira Matuda AG, de Oliveira LD, et al. Effect of passive ultrasonic ırrigation over organic tissue of simulated ınternal root resorption. Int J Dent. 2021;2021:3130813. [Crossref]  [PubMed]  [PMC] 
  26. Koc S, Er K, Hajguliyeva G, Osmanlı Z, Cabbarova L, Karayılmaz H. Pulp tissue dissolution capacities of different irrigation agitation techniques in artificial internal resorption cavities. Eur Oral Res. 2024;58(2):64-9. [PubMed]  [PMC] 
  27. Monteiro LPB, de Sousa SEM, de Castro RF, da Silva EJNL, da Silva Brandão JM. Mechanical activation with easy clean device enhanced organic tissue removal from simulated internal root resorption in a laboratory evaluation. BMC Oral Health. 2023;23(1):385. [Crossref]  [PubMed]  [PMC] 
  28. van der Sluis LW, Wu MK, Wesselink PR. The evaluation of removal of calcium hydroxide paste from an artificial standardized groove in the apical root canal using different irrigation methodologies. Int Endod J. 2007;40(1):52-7. [Crossref]  [PubMed] 
  29. Elnaghy AM, Mandorah A, Elsaka SE. Effectiveness of XP-endo finisher, endoactivator, and file agitation on debris and smear layer removal in curved root canals: a comparative study. Odontology. 2017;105(2):178-83. [Crossref]  [PubMed] 
  30. Bao P, Shen Y, Lin J, Haapasalo M. In Vitro efficacy of XP-endo Finisher with 2 different protocols on biofilm removal from apical root canals. J Endod. 2017;43(2):321-5. [Crossref]  [PubMed] 
  31. Sharki AM, Ali AH. Three-Dimensional measurement of obturation quality of bioceramic materials in filling artificial ınternal root resorption cavities using different obturation techniques: an ın vitro comparative study. J Endod. 2024;50(7):997-1003. [Crossref]  [PubMed] 
  32. Stojicic S, Zivkovic S, Qian W, Zhang H, Haapasalo M. Tissue dissolution by sodium hypochlorite: effect of concentration, temperature, agitation, and surfactant. J Endod. 2010;36(9):1558-62. [Crossref]  [PubMed] 
  33. Jaiswal S, Gupta S, Nikhil V, Bhadoria A, Raj S. Effect of intracanal and extracanal heating on pulp dissolution property of continuous chelation irrigant. J Conserv Dent. 2021;24(6):544-8. [Crossref]  [PubMed]  [PMC] 
  34. Christensen CE, McNeal SF, Eleazer P. Effect of lowering the pH of sodium hypochlorite on dissolving tissue in vitro. J Endod. 2008;34(4):449-52. [Crossref]  [PubMed] 
  35. Wedenberg C, Zetterqvist L. Internal resorption in human teeth--a histological, scanning electron microscopic, and enzyme histochemical study. J Endod. 1987;13(6):255-9. [Crossref]  [PubMed] 

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