Turkiye Klinikleri Journal of Dermatology

.: ORIGINAL RESEARCH
The Evaluation of Staphylococcus aureus Nasal Colonization in Patients with Acute Folliculitis: A Case-control Study
Akut Folikülit Tanılı Hastalarda Staphylococcus aureus Nazal Taşıyıcılığın Değerlendirilmesi: Olgu Kontrol Araştırması
Burcu TUĞRULa, Hatice Gamze DEMİRDAĞb, Funda KEMERİZc, Melike BAHÇECİTAPARd
aClinic of Dermatology, Ankara City Hospital, Ankara, Türkiye
bPrivate Physician, Ankara, Türkiye
cDepartment of Dermatology, Yüksek İhtisas University Faculty of Medicine, Ankara, Türkiye
dDepartment of Statistics, Hacettepe University Faculty of Science, Ankara, Türkiye
Turkiye Klinikleri J Dermatol. 2022;32(2):113-9
doi: 10.5336/dermato.2021-87893
Article Language: EN
Full Text
ABSTRACT
 Objective: The prevalence and incidence of Staphylococcus aureus nasal carriage vary according to the population studied. It is known that there is a link between recurrence of staphylococcal skin infections and nasal carriage. The study aimed to determine the prevalence of S. aureus nasal carriage and microbiological profile of the nasal cultures in patients with acute folliculitis without a history of recurrence, to compare the results with the control group, and to evaluate the demographic factors on bacterial growth. Material and Methods: A case-control study was conducted in a secondary state hospital between May and August 2021. A total of 120 patients diagnosed with acute folliculitis in a dermatology outpatient clinic were enrolled in the study. Patients' demographics including age, gender, job, having a family history of folliculitis, history of visiting a barber regularly, having a health care worker in the family, and localization sites of folliculitis were recorded. Patients' and control groups' microbiological data from nasal swab cultures were also recorded. Results: There was bacterial growth in 29.1% of the patients' nasal cultures. Methicillinsensitive S. aureus was the most frequently isolated microorganism both in the patient and control groups. There was no statistical difference between patients and controls in terms of microbiological profiles and bacterial growth in nasal swab culture. Conclusion: S. aureus nasal colonization of patients with acute folliculitis has similar rates with the healthy population. S. aureus nasal carriage does not appear to be a risk factor and reservoir in patients with acute folliculitis.

Keywords: Folliculitis; Staphylococcus aureus; culture; nasal cavity
ÖZET
 Amaç: Staphylococcus aureus nazal taşıyıcılığının prevalansı ve insidansı, çalışma yapılan toplumlara ve gruplara göre değişkenlik göstermektedir. Stafilokok kaynaklı deri enfeksiyonlarının tekrarlaması ile nazal taşıyıcılık arasında bir bağlantı olduğu bilinmektedir. Bu çalışmada, nüks öyküsü olmayan akut folikülit hastalarında S. aureus nazal taşıyıcılık prevalansı ile nazal kültürlerin mikrobiyolojik profilinin belirlenmesi ve sonuçların kontrol grubu ile karşılaştırılması amaçlanmıştır. Ayrıca demografik faktörlerin, bakteri üremesi üzerindeki etkilerinin değerlendirilmesi de amaçlar arasındadır. Gereç ve Yöntemler: Çalışma olgu kontrol araştırması olarak, ikinci basamak sağlık kuruluşunda yapıldı. Çalışmaya, dermatoloji polikliniğine Mayıs-Ağustos 2021 tarihleri arasında başvuran ve akut folikülit tanısı alan toplam 120 hasta dâhil edildi. Hastaların yaş, cinsiyet ve meslekleri, folikülit lokalizasyonu, ailede folikülit öyküsü, düzenli olarak berbere gitme öyküsü, ailede sağlık çalışanı olup olmadığı ile ilgili bilgiler kaydedildi. Hasta ve kontrol gruplarının nazal sürüntü kültürlerinin mikrobiyolojik verileri de ayrıca kayıt altına alındı. Bulgular: Hastaların nazal kültürlerinde %29,1 oranında bakteri üremesi bulundu. Metisiline duyarlı S. aureus hem hasta hem de kontrol gruplarında oransal olarak en sık izole edilen mikroorganizmaydı. Nazal sürüntü kültüründe mikrobiyolojik profil ve bakteri üremesi açısından hasta ve kontrol grupları arasında istatistiksel fark yoktu. Sonuç: Akut folikülit tanılı hastaların S. aureus nazal kolonizasyon sıklığı, sağlıklı popülasyonla benzer oranlardadır. Akut folikülit hastalarında S. aureus nazal taşıyıcılık, bir risk faktörü ve rezervuar olarak görülmemektedir.

Anahtar Kelimeler: Folikülit; Staphylococcus aureus; kültür; nazal kavite
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