Objective: To evaluate the effect of sedative anesthesia applied during Muller muscle conjunctival resection (MMCR) on the success rate of the surgery. Material and Methods: Data from 41 eyes of 41 patients who underwent MMCR due to mild ptosis between October 2017 and December 2022 were examined retrospectively. The data obtained from 21 patients who received subconjunctival local anesthesia without epinephrine and intravenous midazolam (Group 1) were compared with the data of 20 patients who received only subconjunctival local anesthesia without epinephrine (Group 2). Margin reflex distance 1 (MRD1)>2.5 mm and MRD1<0.5 mm between the two eyes were accepted as success criteria after MMCR. Results: No significant difference was observed between the groups in terms of gender and age distribution (p=0.828 and p=0.961, respectively). Postoperatively, the mean MRD1 in the ptotic eye and the mean MRD1 difference between the two eyes were 4.2±0.2 and 0.4±0.08, respectively, in Group 1 and 4.0±0.1 ve 0.5±0.08 respectively, in Group 2. While MRD1 was found to be significantly higher in Group 1 (p=0.004), the MRD1 difference was significantly higher in Group 2 than Group 1 (p=0.017). The success rate was 95% in Group 1 and 81% in Group 2. Conclusion: We found that the success rate of the MMCR was higher in the group with sedation combined with local anesthetic without epinephrine. We believe that sedation increases patient comfort and surgical success, especially in Muller muscle surgeries where local anesthetics without epinephrine are preferred.
Keywords: Ptosis surgery; Muller muscle; sedation; local anesthesia
Amaç: Müller kası konjonktival rezeksiyonu (MKKR) sırasında uygulanan, sedatif anestezinin operasyonun başarı oranına etkisini değerlendirmek. Gereç ve Yöntemler: Ekim 2017 ve Aralık 2022 yılları arasında hafif derecede pitozis nedeni ile MKKR uygulanan 41 hastanın, 41 gözüne ait veriler geriye dönük incelendi. Epinefrin içermeyen, subkonjonktival lokal anestezi ve intravenöz midazolam uygulanan 21 hastanın (Grup 1) verileri ile sadece subkonjonktival epinefrinsiz lokal anestezi uygulanan 20 hastanın (Grup 2) verileri karşılaştırıldı. MKKR sonrası, marjin refleks mesafesi 1 (MRM1)>2,5 mm olması ve iki göz arasında MRM1 farkının <0,5 mm olması başarı kriteri olarak kabul edildi. Bulgular: Gruplar arasında cinsiyet ve yaş dağılımı açısından anlamlı farklılık izlenmedi (sırasıyla p=0,828 ve p=0,961). Operasyon sonrası pitotik gözde ortalama MRM1 ve iki göz arasında ortalama MRM1 farkı Grup 1 de sırasıyla 4,2±0,2 ve 0,4±0,08 iken Grup 2 de sırasıyla 4,0±0,1 ve 0,5±0,08 idi. MRM1 Grup 1 de anlamlı düzeyde yüksek saptanırken (p=0,004) MRM1 farkı Grup 2 de Grup 1 den anlamlı düzeyde yüksek saptandı (p=0,017). Başarı oranı Grup 1 de %95, Grup 2 de ise %81 olarak saptandı. Sonuç: Epinefrin içermeyen lokal anestezik ile birlikte sedasyon uygulanan grupta, MKKR operasyonun başarı oranının daha yüksek olduğunu saptadık. Özellikle epinefrinsiz lokal anestezik tercih edilecek olan Müller kası cerrahilerinde sedatif anestezinin hasta konforunu ve operasyon başarısını arttırdığını düşünüyoruz.
Anahtar Kelimeler: Pitozis cerrahisi; Müller kası; sedasyon; lokal anestezi
- Putterman AM, Urist MJ. Müller muscle-conjunctiva resection. Technique for treatment of blepharoptosis. Arch Ophthalmol. 1975;93(8):619-23. [Crossref] [PubMed]
- Cohen LM, Rootman DB. Blepharoptosis repair: external versus posterior approach surgery: why I select one over the other. Facial Plast Surg Clin North Am. 2021;29(2):195-208. [Crossref] [PubMed]
- Leung VC, Dupuis JE, Ashraf DC, Idowu OO, Massicotte E, Vagefi MR, et al. Müller muscle conjunctival resection: a multicentered prospective analysis of surgical success. Ophthalmic Plast Reconstr Surg. 2023;39(3):226-31. Erratum in: Ophthalmic Plast Reconstr Surg. 2023;39(3):304. [Crossref] [PubMed]
- Dan J, Sinha KR, Rootman DB. Predictors of success following müller's muscle-conjunctival resection. Ophthalmic Plast Reconstr Surg. 2018;34(5):483-6. [Crossref] [PubMed]
- Rootman DB, Karlin J, Moore G, Goldberg R. The role of tissue resection length in the determination of post-operative eyelid position for Muller's muscle-conjunctival resection surgery. Orbit. 2015;34(2):92-8. [Crossref] [PubMed]
- Mohammad S, Hussain A. Outcomes of conjunctival-Müller's muscle resection surgery with and without epinephrine in local anesthetic. Orbit. 2022;41(1):84-8. [Crossref] [PubMed]
- Bartley GB, Lowry JC, Hodge DO. Results of levator-advancement blepharoptosis repair using a standard protocol: effect of epinephrine-induced eyelid position change. Trans Am Ophthalmol Soc. 1996;94:165-73; discussion 174-7. [PubMed] [PMC]
- Sajja K, Putterman AM. Müller's muscle conjunctival resection ptosis repair in the aesthetic patient. Saudi J Ophthalmol. 2011;25(1):51-60. [Crossref] [PubMed] [PMC]
- Matsuda H, Kabata Y, Takahashi Y, Hanzawa Y, Nakano T. Influence of epinephrine contained in local anesthetics on upper eyelid height in transconjunctival blepharoptosis surgery. Graefes Arch Clin Exp Ophthalmol. 2020;258(6):1287-92. [Crossref] [PubMed]
- Lake S, Mohammad-Ali FH, Khooshabeh R. Open sky müller's muscle-conjunctiva resection for ptosis surgery. Eye (Lond). 2003;17(9):1008-12. [Crossref] [PubMed]
- Waqar S, McMurray C, Madge SN. Transcutaneous blepharoptosis surgery-advancement of levator aponeurosis. Open Ophthalmol J. 2010;4:76-80. [Crossref] [PubMed] [PMC]
- Yanagidate F, Strichartz GR. Local anesthetics. Handb Exp Pharmacol. 2007;(177):95-127. [Crossref] [PubMed]
- Neal JM. Effects of epinephrine in local anesthetics on the central and peripheral nervous systems: neurotoxicity and neural blood flow. Reg Anesth Pain Med. 2003;28(2):124-34. [Crossref] [PubMed]
- Strosberg AD. Structure, function, and regulation of adrenergic receptors. Protein Sci. 1993;2(8):1198-209. [Crossref] [PubMed] [PMC]
- Esmaeli-Gutstein B, Hewlett BR, Pashby RC, Oestreicher J, Harvey JT. Distribution of adrenergic receptor subtypes in the retractor muscles of the upper eyelid. Ophthalmic Plast Reconstr Surg. 1999;15(2):92-9. [Crossref] [PubMed]
- Putterman AM, Fett DR. Müller's muscle in the treatment of upper eyelid ptosis: a ten-year study. Ophthalmic Surg. 1986;17(6):354-60. [Crossref] [PubMed]
- Rootman DB, Sinha KR, Goldberg RA. Change in eyelid position following muller's muscle conjunctival resection with a standard versus variable resection length. Ophthalmic Plast Reconstr Surg. 2018;34(4):355-60. [Crossref] [PubMed]
- Zatezalo CC, Tavakoli M, Ayala-Haedo J, Callaway NF, Ko MJ, Anagnostopoulos AG, et al. A prospective randomized comparative clinical trial to analyze pain and surgical outcomes between frontal nerve blocks and subconjunctival anesthesia for conjunctival mullerectomy resection. Ophthalmic Plast Reconstr Surg. 2018;34(6):575-8. [Crossref] [PubMed]
- Han HH, Kim MS. Transconjunctival müller's muscle tucking method for non-incisional correction of mild ptosis: the effectiveness and maintenance. Aesthetic Plast Surg. 2019;43(4):938-45. [Crossref] [PubMed]
- El-Saadani, Mandour SS, Ramadan AE. Müller's muscle-conjunctival resection for blepharoptosis repair. Menoufia Med J. 2015;28:954-9. [Crossref]
- Guo Z, Park DDH, Park K, Guo N. Three different anesthesia approaches in blepharoptosis surgery. Plast Reconstr Surg Glob Open. 2019;7(4):e2136. [Crossref] [PubMed] [PMC]
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