Turkiye Klinikleri Journal of Health Sciences

.: ORIGINAL RESEARCH
The Acute Effect of Exercise Test on Exhaled Carbon Monoxide Rate
Egzersiz Testinin Ekshale Karbon Monoksit Oranı Üzerindeki Akut Etkisi
Hazal YAKUTa, Sevgi ÖZALEVLİa, Oğuz KILINÇb
aSchool of Physical Therapy and Rehabilitation, Dokuz Eylül University, İzmir, TURKEY
bDepartment of Pulmonology and Critical Care, Dokuz Eylül University Faculty of Medicine, İzmir, TURKEY
Turkiye Klinikleri J Health Sci. 2021;6(2):267-73
doi: 10.5336/healthsci.2020-75826
Article Language: EN
Full Text
ABSTRACT
 Objective: The aim of this study is to analyze the acute effect of exercise on the rate of exhaled carbon monoxide (CO) in healty young smokers. Material and Methods: Twenty four male smokers were included in the study. Pulmonary functions of the participants were evaluated by spirometer forced expiratory volume in one second (FEV1), forced vital capacity (FVC), FEV1/FVC, peak flow rate (PEF) and forced expiratory flow at 25 to 75% of FVC (FEF 25%-75%). Exercise testing was performed by using bicycle ergometer. Maximal load, maximum oxygen uptake (VO2max), rest and maximal heart rate were recorded. CO levels before and after the test were mesured with portable breath CO monitor. CO levels and changes were assessed and compared on the exercise test day and rest day (without exercise test). Results: 25% of the participants have dyspnea, 20.8% have cough and 50% have sputum complaints. The results of the pulmonary function test and exercise test of young healthy smokers are as follows: % FEV1=89.7±9.9, % FEV1/FVC=87.4±8.2, % PEF=77.4±9.5, mean rest heart rate=94.8±9.8 bpm, mean maximal heart rate=170.3±9.7 bpm and mean VO2max=30.9±6.5 mL/min/kg. There is a statistically significant difference between the first and the second CO values of the participants measured on both days (p<0.001). There is a significant difference between the mean change of CO on the exercise test day and rest day (p<0.001). Conclusion: Our results show that smoking causes respiratory symptoms, impaired cardiopulmonary responses to exercise and increased CO level and exercise increases to the exhaled CO rate in young and healthy male.

Keywords: Smokers; carbon monoxide; exercise; pulmonary function
ÖZET
 Amaç: Bu çalışmanın amacı, sigara içen genç sağlıklı bireylerde egzersizin ekshale karbon monoksit (CO) oranı üzerindeki akut etkisinin araştırılmasıdır. Gereç ve Yöntemler: Çalışmaya sigara içen 24 erkek birey dâhil edildi. Katılımcıların solunum fonksiyonları spirometri birinci sn zorlu ekspirasyon volümü [forced expiratory volume in one second (FEV1)], zorlu vital kapasite [forced vital capacity (FVC)], FEV1/FVC, tepe akım hızı [peak flow rate (PEF)], FVC'nin %25 ile 75'inde zorlu ekspiratuar akış (FEF %25-75) ile değerlendirildi. Egzersiz testi bisiklet ergometresi kullanılarak yapıldı ve test sırasında maksimum yük, maksimum oksijen tüketimi (VO2max), istirahat ve maksimum kalp hızı değerleri kaydedildi. Bireylerin CO düzeyleri egzersiz testi öncesi ve sonrası portatif CO cihazı ile ölçüldü. CO düzeyleri ve değişiklikler egzersiz testinin yapıldığı gün ve (egzersiz testinin yapılmadığı) istirahat gününde değerlendirildi ve karşılaştırıldı. Bulgular: Katılımcıların %25'inde dispne, %20,8'inde öksürük ve %50'sinde balgam şikâyeti bulunmaktadır. Katılımcıların solunum fonksiyon testi ve egzersiz testi sonuçları şöyledir: % FEV1=89,7±9,9, % FEV1/FVC=87,4±8,2, % PEF=77,4±9,5, ortalama istirahat kalp hızı=94,8±9,8, ortalama maksimum kalp hızı=170,3±9,7 ve ortalama VO2max=30,9±6,5 mL/min/kg. Katılımcıların her 2 gün ölçülen 1. ve 2. CO değerleri arasında istatistiksel olarak anlamlı bir fark vardır (p<0.001). Egzersiz testi yapılarak değerlendirilen CO değişimi ile egzersiz testi yapılmadan değerlendirilen CO değişimi arasında istatistiksel olarak anlamlı bir fark vardır (p<0.001). Sonuç: Bu çalışmaya katılan genç ve sağlıklı erkeklerde sigara tüketimi solunumsal semptomlara, egzersize verilen kardiyopulmoner yanıtların bozulmasına ve CO seviyesinin artmasına neden olmuştur. Bu bireylerde atılan CO miktarının egzersizle birlikte daha fazla olduğu görülmüştür.

Anahtar Kelimeler: Sigara içicileri; karbon monoksit; egzersiz; pulmoner fonksiyon
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