Objective: Organ preservation strategy in laryngeal carcinoma is now the fundamental treatment choice in laryngeal carcinoma. Endolaryngeal surgery (ELS) is one of the successful treatment modalities for organ preservation. With the introduction of transoral robotic surgery (TORS) into glottic laryngeal cancer treatmet options, TORS failure patient management became more important for surgeons interested in head and neck surgery. The aim of this study was to evaluate the functional results, local control, and survival rates in a series of 7 patients who were consecutively managed with Supracricoid Partial Laryngectomy (SCPL) for persistent and recurrence tumors after TORS cordectomy. Material and Methods: Patients who underwent SCPL after failed TORS cordectomy over a seven-year period were enrolled in the study. The patients' age, sex, previous cordectomy type, tumor stage, recurrence interval, recurrence stage, neck dissection adjuvant therapy, decannulation time, and start to oral feeding type were recorded. Results: After salvage surgery, the mean decannulation time was 17.4±3.49 days in 5 patients who could be decannulated. The mean oral intake time was 26.57±23.66 days. The recurrence rate was 14.28% (1/7). The local control rate and organ preservation rate was 85.72%. The functional preservation rate was 71.42%. All patients are feeding orally (100%). Conclusion: With suitable oncologic and functional rates, SCPL is a feasible surgical choice after TORS failure.
Keywords: Glottic cancer; partial laryngectomy; recurrence; robotic surgery; larynx
Amaç: Laringeal karsinomlardada organ koruma stratejisi, temel tedavi seçeneğidir. Endolaringeal cerrahi (ELS) organ korunmasında başarılı tedavi yöntemlerinden biridir. Transoral robotik cerrahinin (TORS) glottik laringeal kanser tedavi seçeneklerine girmesiyle, TORS sonrası nüks etmiş hastaların yönetimi baş ve boyun cerrahisi ile ilgilenen cerrahlar için daha önemli hale gelmiştir. Bu çalışmanın amacı, TORS kordektomi sonrası nüks eden ve Suprakrikoid Parsiyel Larenjektomi (SKPL) ile tedavi edilen 7 hastadan oluşan bir seride fonksiyonel sonuçları, lokal kontrol ve sağkalım oranlarını değerlendirmektir. Gereç ve Yöntemler: Yedi yıl içinde TORS kordektomisi sonrası nüks eden ve SKPL uygulanan hastalar çalışmaya alındı. Hastaların yaşı, cinsiyeti, önceki kordektomi tipi, tümör evresi, nüks aralığı, nüks evresi, boyun diseksiyonu adjuvan tedavisi, dekanülasyon süresi ve oral beslenmeye geçilme süresi kaydedildi. Bulgular: Kurtarma ameliyatından sonra, dekanüle edilebilen 5 hastada ortalama dekanülasyon süresi 17,4 ±3,49 gündü. Ortalama oral alım süresi 26,57±23,66 gündü. Nüks oranı %14,28 (1/7) idi. Lokal kontrol oranı ve organ koruma oranı %85,72 idi. Fonksiyon koruma oranı %71,42 idi. Tüm hastalarda oral yolla beslenme sağlandı (%100). Sonuç: Uygun onkolojik ve fonksiyonel oranlar ile TORS başarısızlığından sonra SKPL uygun bir cerrahi seçimdir.
Anahtar Kelimeler: Glottik kanser; parsiyel larinjektomi; rekürrens; robotik cerrahi; larinks
- Rettig EM, D?Souza G. Epidemiology of head and neck cancer. Surg Oncol Clin N Am. 2015;24(3):379-96. [Crossref] [PubMed]
- Warner L, Chudasama J, Kelly CG, Loughran S, McKenzie K, Wight R, et al. Radiotherapy versus open surgery versus endolaryngeal surgery (with or without laser) for early laryngeal squamous cell cancer. Cochrane Database Syst Rev. 2014;12(12):CD002027.[Crossref] [PubMed]
- Mendelsohn AH, Remacle M. Transoral robotic surgery for laryngeal cancer. Curr Opin Otolaryngol Head Neck Surg. 2015;23(2):148-52. [Crossref] [PubMed]
- Marioni G, Marchese-Ragona R, Kleinsasser NH, Lionello M, Lawson G, Hagen R, et al. Partial laryngeal surgery in recurrent carcinoma. Acta Otolaryngol. 2015;135(2):119-24.[Crossref] [PubMed]
- Marioni G, Marchese-Ragona R, Pastore A, Staffieri A. The role of supracricoid laryngectomy for glottic carcinoma recurrence after radiotherapy failure: a critical review. Acta Otolaryngol. 2006;126(12):1245-51. [Crossref] [PubMed]
- Paleri V, Thomas L, Basavaiah N, Drinnan M, Mehanna H, Jones T. Oncologic outcomes of open conservation laryngectomy for radiorecurrent laryngeal carcinoma: a systematic review and meta-analysis of English-language literature. Cancer. 2011;117(12):2668-76.[Crossref] [PubMed]
- Lucioni M, Bertolin A, Lionello M, Giacomelli L, Rizzotto G, Marioni G. Open partial horizontal laryngectomy for salvage after failure of CO₂ laser-assisted surgery for glottic carcinoma. Eur Arch Otorhinolaryngol. 2016;273:169-75. [Crossref] [PubMed]
- Compton CC, Byrd DR, Garcia-Aguilar jJ, Kurtzman SH, Olawaiye A, Washington MK. AJCC Cancer Staging 7th Atlas. 2nd ed. New York, NY: Springer; 2010. p.79-90.
- Remacle M, van Haverbeke C, Eckel H, Bradley P, Chevalier D, Djukic V, et al. Proposal for revision of the European Laryngological Society classification of endoscopic cordectomies. Eur Arch Otorhinolaryngol. 2007;264(5):499-504. [Crossref] [PubMed]
- Cohen EE, LaMonte SJ, Erb NL, Beckman KL, Sadeghi N, Hutcheson KA, et al. American Cancer Society head and neck cancer survivorship care guideline. CA Cancer J Clin. 2016;66(3):203-39. [Crossref] [PubMed]
- Leone CA, Capasso P, Topazio D, Russo G. Supracricoid partial laryngectomy for recurrent laryngeal cancer after chemoradiotherapy: a systematic review and meta-analysis. Acta Otorhinolaryngol Ital. 2016;36(6):439-49.
- Huang J, Yu Z, Fang J, Chen X, Chen X, Huang Z. Salvage transoral laser microsurgery for early recurrent glottic carcinoma after primary laser treatment. Acta Otolaryngol. 2013;133(5):531-7. [Crossref] [PubMed]
- Bertino G, Degiorgi G, Tinelli C, Cacciola S, Occhini A, Benazzo M. CO ₂ laser cordectomy for T1-T2 glottic cancer: oncological and functional long-term results. Eur Arch Otorhinolaryngol. 2015;272(9):2389-95. [Crossref] [PubMed]
- Roedel RM, Matthias C, Wolff HA, Christiansen H. Repeated transoral laser microsurgery for early and advanced recurrence of early glottic cancer after primary laser resection. Auris Nasus Larynx. 2010;37(3):340-6.[Crossref] [PubMed]
- Canis M, Ihler F, Martin A, Matthias C, Steiner W. Transoral laser microsurgery for T1a glottic cancer: review of 404 cases. Head Neck. 2015;37(6):889-95. [Crossref] [PubMed]
- Ansarin M, Cattaneo A, De Benedetto L, Zorzi S, Lombardi F, Alterio D, et al. Retrospective analysis of factors influencing oncologic outcome in 590 patients with early-intermediate glottic cancer treated by transoral laser microsurgery. Head Neck. 2017;39(1):71-81.[Crossref] [PubMed]
- Mortuaire G, Francois J, Wiel E, Chevalier D. Local recurrence after CO2 laser cordectomy for early glottic carcinoma. Laryngoscope. 2006;116(1):101-5. [Crossref] [PubMed]
- Lallemant B, Chambon G, Garrel R, Kacha S, Rupp D, Galy-Bernadoy C, et al. Transoral robotic surgery for the treatment of T1-T2 carcinoma of the larynx: preliminary study. Laryngoscope. 2013;123(10):2485-9. [Crossref] [PubMed]
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