Turkiye Klinikleri Journal of Pediatrics

.: ORIGINAL RESEARCH
Researching the Presence of P Dispersion Among Children of Adult Patients with Idiopathic Atrial Fibrillation
İdiyopatik Atriyal Fibrilasyonlu Erşkinlerin Çocuklarında P Dalga Dispersiyonu Varlığının Değerlendirilmesi
Serkan Bilge KOCAa, Senem ÖZGÜRb, Selmin KARADEMİRb, Süleyman KALAYCIc
aClinic of Endocrinology, Denizli State Hospital, Denizli, TURKEY
bClinic of Pediatric Cardiology, Dr. Sami Ulus Children Training and Research Hospital, Ankara, TURKEY
cClinic of Cardiology, Zonguldak Atatürk State Hospital, Zonguldak, TURKEY
Turkiye Klinikleri J Pediatr. 2021;30(1):22-30
doi: 10.5336/pediatr.2020-75455
Article Language: EN
Full Text
ABSTRACT
 Objective: Interatrial and intraatrial conduction problems were detected in individiuals with atrial fibrillation (AF). Genetic studies in AF patients has been suggested that atrial and ventricular arrhythmias are both associated with common genes. The conduction patterns in atrial arrhythmias are defined by P-wave dispersion (PWD) index. Material and Methods: Twenty six children of 16 idiopathic AF patients and 29 healthy children from 29 different families were enrolled in the study. One group had a family history of idiopathic AF, in one of the parents. Electrocardiography findings [heart rate, rhythm, maximum (max) and minimum (min) durations of P wave, QT, QTc intervals, and also dispersions] were recorded. Electronic ruler measurement mean values were calculated from 3 subsequent cycles of the DII derivation. Results: Comparing the factors of Pmin, QRS, QTmax, QTmin, QTd, QTcmax, QTcmin, QTc dispersion and J point-T peak time, no significant difference was detected between the two groups (p>0.05). Pmax and PWD (108.4±11 ms versus 94.2±9.6 ms and 54±11 ms versus 43±9 ms p

Keywords: Atrial fibrillation; child; electrocardiography
ÖZET
 Amaç: Sinüs uyarılarının intraatriyal ve interatriyal ileti sürelerinde uzama atriyal fibrilasyon (AF) bulunan hastalarda gözlenen temel elektrofizyolojik bozukluklardandır. Genetik çalışmalarda idiyopatik atriyal ve ventriküler aritmilerin benzer genlerle ilişkisi saptanmıştır. Atriyal aritmili hastalardaki iletim kalıbı, P dalga dispersiyonu [P-wave dispersion (PWD)] adı verilen indeksle değerlendirilmektedir. Gereç ve Yöntemler: Çalışmaya 16 erişkin idiyopatik AF hastasının 26 sağlıklı çocuğu ve 29 farklı aileden 29 sağlıklı çocuk dâhil edildi. Ebeveynlerinden birinde idiyopatik AF olan çocuklar ve aile öyküsünde kalp hastalığı bulunmayan sağlıklı çocuklarda elektrokardiyografi bulguları [kalp hızı, ritim, P dalgası, QT ve QTc intervallerinin maksimum (maks) ve minimum (min) süreleri, QT, QTc ve PWD] kaydedildi. Ölçümler D II derivasyonundan elde edilerek bilgisayar ortamında elektronik hassas cetvel ile üç ardışık derivasyon ölçümlerinin ortalaması alındı. Bulgular: Çalışma grubunda sırasıyla Pmaksve PWD daha yüksek (108,4±11 ms; 94,2±9,6 ms, 54±11 ms; 43±9 ms p0,05). Sonuç: PWD, presemptomatik evredeki AF olasılığını belirlemek için kullanılabilir. Aile öyküsünde idiyopatik AF olan çocukların erişkin dönemde AF geliştirme açısından uzun dönemde izlenmesi ve sonuçlarını içeren yeni çalışmalara ihtiyaç vardır.

Anahtar Kelimeler: Atriyal fibrilasyon; çocuk; elektrokardiyografi
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