Turkiye Klinikleri Journal of Ophthalmology

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Prematüre Retinopatisi İçin Uygulanan İntravitreal Enjeksiyon Sonrası Gelişen İyatrojenik Lens Opasitesi
The Iatrogenic Lens Opacity Developed After Intravitreal Injection for Premature Retinopathy
Halil İbrahim ATEŞOĞLUa , Özdemir ÖZDEMİRb
aTatvan Devlet Hastanesi, Göz Hastalıkları Kliniği, Bitlis, Türkiye
bSağlık Bilimleri Üniversitesi Ankara Şehir Hastanesi, Göz Hastalıkları AD, Ankara, Türkiye
Turkiye Klinikleri J Ophthalmol. 2024;33(2):133-6
doi: 10.5336/ophthal.2023-101159
Article Language: TR
Full Text
ÖZET
 Yirmi dördüncü haftada 550 g olarak doğan ve postmenstrüel 33. haftadaki göz muayenesinde her iki gözde Zon I'de 12 saat kadranı Evre 1 prematüre retinopatisi ile arterio-venöz şantların ve retinal hemorajilerin eşlik ettiği yoğun plus hastalık bulunan olguya agresif prematüre retinopati tanısı konuldu. Olgunun her iki gözüne anti-vasküler endotelyal büyüme faktörü ajanlarından bevasizumab uygulanması kararı alındı. Her iki gözüne intravitreal 0,3 mg/0,0125 mL bevasizumab enjeksiyonu yapılan olgunun postoperatif birinci gün muayenesinde, sol gözde intravitreal enjeksiyon iğnesinin lens arkasına temas ettiği görüldü. Bu lezyon ilerleyen günlerde lens arka kapsülünde küçük bir lens opasitesine dönüştü. Fakat lens opasitesi görsel aksı kapatmadığı için takip edilmesine karar verildi.

Anahtar Kelimeler: Bevasizumab; enjeksiyon; katarakt; prematüre retinopatisi; vasküler endotelyal büyüme faktörü
ABSTRACT
 Aggressive retinopathy of prematurity was detected at the 33rd postmenstrual week in a patient who was born 550 g at 24 weeks, had Stage 1 retinopathy of prematurity in Zone I at 12 hour quadrants and plus disease with arterio-venous shunts and retinal hemorrhages in both eyes. It was decided to apply bevacizumab, an antivascular endothelial growth factor agent, to both eyes of the patient. 0.3 mg/0.0125 mL intravitreal bevacizumab was injected into both eyes. In the eye examination performed on the first postoperative day, it was observed that the intravitreal injection needle contacted the back of the lens in the left eye. This lesion turned into a small lens opacity in the posterior lens capsule in the following days. However, since the lens opacity did not obscure the visual axis, it was decided to follow up.

Keywords: Bevacizumab; injection; cataract; retinopathy of prematurity; vascular endothelial growth factor
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