Anemia comprises various causative factors such as traumatic blood loss, insufficient intake of essential nutrients for red blood cell production (iron, B12 or folic acid), chronic diseases, thalassemia or enzymatic abnormalities along with bone marrow suppression caused by various factors. This study aimed at exploring the impact and effectiveness of pharmacist on management of anemia-related issues. A comprehensive literature review was undertaken from various databases like PubMed®, ScienceDirect®, Google Scholar® and Web of Science® to gather relevant information. Clinical studies investigating the effects of pharmaceutical care on anemia treatment were included into this review. According to available literature findings suggest that pharmacist-led intervention improve the level of adherence to medical recommendations given to patients thus resulting in higher quality levels delivered through enhanced healthcare practices leading to favorable health outcomes especially concerning anemic conditions where patients require compliance with complex medical regimens. Pharmaceutical care provided by the pharmacist leads to healthy consumption levels of iron supplements. These services result in lower costs as well as increased haemoglobin levels. In addition, cognitive pharmacy services reduce the workload of physicians, resulting in less risk of drug overdose among patients. Hence pharmacists must play a more active role during anemia treatment management to improve patient outcomes.
Keywords: Anemia; pharmacist; pharmaceutical care; evidence-based pharmaceutical care; anemia treatment
Anemi, kan kaybı, eritrositlerin üretimi için gerekli besinlerin (demir, B12 veya folik asit) yetersiz alımı, kronik hastalıklar, talasemi veya enzimatik anormallikler ile belirli ilaçların neden olduğu kemik iliği baskılanması gibi çeşitli nedensel faktörlerden dolayı ortaya çıkan bir durumdur. Bu çalışma, eczacıların anemi ile ilgili sorunların yönetimi ve tedavisi üzerindeki etkisini ve etkinliğini araştırmayı amaçlamıştır. PubMed®, ScienceDirect®, Google Scholar® ve Web of Science® veri tabanlarından kapsamlı bir literatür taraması yapılarak, eczacılar tarafından yürütülen, anemik hastaların tedavisine yönelik farmasötik bakımla ilgili klinik çalışmalar ve eczacıların sağlık hizmeti sunumu sırasında hastalara sundukları hizmetler aracılığıyla anemi tedavisi ve yönetimi gibi sağlık durumunu iyileştirmeye yönelik katkıları derlenmiştir. Mevcut literatür bulgularına göre eczacıların yönettiği anemi tedavisinde, hastalara verilen farmasötik bakım hizmeti uyum düzeyini artırmakta ve böylece hastaların karmaşık tıbbi rejimlere uyum sağlamalarını gerektiren anemik durumlarla ilgili olarak faydalı sağlık sonuçlarına yol açarak tedaviden elde edilerek faydayı artırmaktadırlar. Eczacı tarafından sunulan farmasötik bakım hizmeti, demir takviyelerinin akılcı ilaç kullanımı çerçevesinde kullanılmasınayol açmaktadır. Bu hizmetler hemoglobin düzeylerinin yükselmesinin yanı sıra daha düşük maliyetlerle sonuçlanmaktadır. Ayrıca kognitif eczacılık hizmetleri hekimlerin iş yükünü azaltırken, hastalar arasında daha az ilaç doz aşımı riskine neden olmaktadır. Bu nedenle eczacılar, hasta sonuçlarını iyileştirmek için anemi tedavisi yönetimi sırasında daha aktif bir rol oynamalıdır.
Anahtar Kelimeler: Anemi; eczacı; farmasötik bakım; kanıta dayalı farmasötik bakım; anemi tedavisi
- Saibaba S, Ramu B. Role of community pharmacist in management of anaemia. Pharmacy & Pharmacology International Journal. 2018;6(3):216-20. [Crossref]
- Vieth JT, Lane DR. Anemia. Emerg Med Clin North Am. 2014;32(3):613-28. [Crossref] [PubMed]
- Turner J, Parsi M, Badireddy M. Anemia. StatPearls Publishing. 2022. [Link]
- Peng YF, Zhang QS, Luo WG. The clinical usefulness of mean corpuscular hemoglobin concentration in patients with pneumoconiosis. Int J Gen Med. 2023;16:3171-7. [Crossref] [PubMed] [PMC]
- Manolakis PG, Skelton JB. Pharmacists' contributions to primary care in the United States collaborating to address unmet patient care needs: the emerging role for pharmacists to address the shortage of primary care providers. Am J Pharm Educ. 2010;74(10):S7. [Crossref] [PubMed] [PMC]
- Marouf BH, Ahmed Yusif I, Najim RH. Role of pharmacist intervention in the management of anemia associated with chronic kidney diseases at the hemodialysis setting. Journal of Young Pharmacists: 2020;12(2):162-8. [Crossref]
- Tahaineh LM, Khasawneh AH. A randomised control trial to evaluate the clinical pharmacist's role in managing iron deficiency anaemia patients. Int J Pharm Pract. 2018;26(1):55-62. [Crossref] [PubMed]
- Nasir BB, Fentie AM, Adisu MK. Adherence to iron and folic acid supplementation and prevalence of anemia among pregnant women attending antenatal care clinic at Tikur Anbessa Specialized Hospital, Ethiopia. PLoS One. 2020;15(5):e0232625. [Crossref] [PubMed] [PMC]
- Bahnasawy SM, El Wakeel LM, Beblawy NE, El-Hamamsy M. Clinical pharmacist-provided services in iron-overloaded beta-thalassaemia major children: a new insight into patient care. Basic Clin Pharmacol Toxicol. 2017;120(4):354-9. [Crossref] [PubMed]
- Heryadi PL, Sauriasari R, Andrajati R. The influence of pharmacist counseling on changes in hemoglobin levels of pregnant women at a community health center in Indonesia. Asian Journal of Pharmaceutical and Clinical Research. 2017;10(Special Issue October):114-15. [Crossref]
- Debenito JM, Billups SJ, Tran TS, Price LC. Impact of a clinical pharmacy anemia management service on adherence to monitoring guidelines, clinical outcomes, and medication utilization. J Manag Care Spec Pharm. 2014;20(7):715-20. [Crossref] [PubMed] [PMC]
- Han J, Bhat S, Gowhari M, Gordeuk VR, Saraf SL. Impact of a clinical pharmacy service on the management of patients in a sickle cell disease outpatient center. Pharmacotherapy. 2016;36(11):1166-72. [Crossref] [PubMed] [PMC]
- Ohnishi J, Miyake A, Kuwatsuka K, Onoue Y, Lee M, Koyama T, et al. Effect of pharmacist management on serum hemoglobin levels with renal anemia in hemodialysis outpatients. Biol Pharm Bull. 2011;34(10):1609-12. [Crossref] [PubMed]
- Weil E, Oxencis C. Pharmacist collaborative practice agreement for the management of anemia in malignant disease with erythropoiesis-stimulating agents. Support Care Cancer. 2015;23(8):2507-13. [Crossref] [PubMed]
- van den Oever FJ, Heetman-Meijer CFM, Birnie E, Vasbinder EC, Swart EL, Schrama YC. A pharmacist-managed dosing algorithm for darbepoetin alfa and iron sucrose in hemodialysis patients: A randomized, controlled trial. Pharmacol Res Perspect. 2020;8(4):e00628. [Crossref] [PubMed] [PMC]
- Wall G, Sharma V, Taylor MJ, Schneider R, Adams K, Gasperi L, et al. Retrospective safety evaluation of a pharmacist-assisted total dose iron sucrose protocol in hospital inpatients with iron deficiency anemia. J Pharm Pract. 2021;34(4):573-6. [PubMed]
- Walton T, Holloway KP, Knauss MD. Pharmacist-managed anemia program in an outpatient hemodialysis population. Hospital Pharmacy. 2005;40(12):1057-6. [Crossref]
- Wee HL, Seng BJ, Lee JJ, Chong KJ, Tyagi P, Vathsala A, et al. Association of anemia and mineral and bone disorder with health-related quality of life in Asian pre-dialysis patients. Health Qual Life Outcomes. 2016;14:94. [Crossref] [PubMed] [PMC]
.: Process List