Turkiye Klinikleri Journal of Anesthesiology Reanimation

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Perkütan Nefrolitotomilerde Hemodinamik, Metabolik ve Elektrolit Değişiklikleri
Haemodynamic, Metabolic and Electrolyte Changes During Percutaneous Nephrolithotomy
Sıtkı GÖKSUa, Mehri T. CENGİZa, Ayşe MIZRAKa, Senem KORUKa, Gülşen TANRIVERDİa, Ünsal ÖNERa
aAnesteziyoloji ve Reanimasyon AD, Gaziantep Üniversitesi Tıp Fakültesi, Gaziantep
Turkiye Klinikleri J Anest Reanim. 2011;9(2):79-83
Article Language: TR
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Amaç: Perkütan nefrolitotomi esnasında böbreklerin devamlı irrigasyonu, aşırı su absorbsiyonuna ve hidrostatik basıncın artışına neden olabilir. Sonuçta intravasküler volümde metabolik, endokrin ve hemodinamik değişiklikler görülebilir. Çalışmamızın amacı, perkütan nefrolitotomi uygulanan hastalarda, irrigasyon solüsyonu olarak %0,9'luk serum fizyolojik kullanıldığında meydana gelen hemodinamik, elektrolit ve metabolik değişiklikleri araştırmaktır. Gereç ve Yöntemler: Perkütan nefrolitotomi yapılacak olan 15-65 yaş arası ASA I-II grubunda 35 hasta çalışmaya alındı. Hematokrit, üre ve kreatinin değerleri, kan basınçları, KAH (Kalp Atım Hızı), kan gazları ve elektrolit değerleri irrigasyondan önce, irrigasyon esnasında, 15, 30, 60. dakikalarda, erken post- operatif dönemde ve operasyondan 24 saat sonra kaydedildi. Ayrıca irrigasyon, anestezi ve cerrahi süreleri, irrigasyon volümü kaydedildi. Bulgular: Ortalama yaş 36,14 ± 14,46 yıl ve kadın/erkek oranı 16/19 idi. Sistolik ve diastolik kan basınçları, KAH, elektrolitler, üre ve kreatinin düzeylerinde irrigasyondan önceki (kontrol) değerler ile irrigasyon sırası ve sonrasındaki değerlere göre istatistiksel farklılık yoktu (p>0,05). Arteriyel kan gazındaki tüm parametrelerde (pH, PaO2, PaCO2, HCO3, BE, Hematokrit) kontrol değerlerine göre istatistiksel olarak anlamlı farklılık vardı (p< 0,05). PaO2'deki değişiklikler irrigasyon süresi, cerrahi süre ve anestezi süresi ile korele bulundu. Hemodinamik değişiklikler, üre ve kreatinin değerleri ile anestezi, cerrahi ve irrigasyon süresi ve volümü, perkütan girişim sayısı arasında korelasyon yoktu. Sonuç: Perkütan nefrolitotomi uygulanan hastalarda, özellikle renal ve metabolik bozukluğu varsa düzenli arteriyel kan gazı ve hematokrit takiplerinin yapılmasını tavsiye ederiz.

Anahtar Kelimeler: Nefrostomi, perkütan; asid-baz dengesi; irrigasyon
ABSTRACT
Objective: The continuous irrigation may cause the excessive fluid absorption and an increase in hydrostatic pressure during percutaneous nephrolithotomy. At the end of procedure, metabolic, endocrine and haemodynamic changes may occur. We aimed to investigate the changes occurred during the use of 0.9%NaCl as the irrigation solution in the patients undergoing percutaneous nephrolithotomy. Material and Methods: 35 patients (15-65 yrs ASA I-II) undergoing percutaneous nephrolithotomy were enrolled to the study. Haematocrit, urea and creatinine values, blood pressures, HR (heart rate), blood gases and electrolytes were recorded before irrigation, during irrigation at 15, 30, 60th min and at early period and postoperative 24th hour. Durations of anaesthesia, operation and irrigation; volumes of irrigation fluid used were also recorded. Results: The mean age was 36.14 ± 14.46 years and the sex ratio was 16/19 (F/M). There was no difference between the values before irrigation such as systolic and diastolic blood pressures, HR, electrolytes, urea, creatinine and the same kind values during and after irrigation (p> 0.05). There was a statistically important difference in all parameters of arterial gases (pH, PaO2, PaCO2, HCO3, BE, Haematocrit) between the control values (p< 0.05). It was found that the changes in PaO2 were correlated with the durations of irrigation, operation, anaesthesia. There was no correlation with the haemodynamic changes, urea, creatinine values and the durations of anaesthesia, operation, irrigation and volume, and number of percutaneous interventions. Conclusion: It is advisable to monitor arterial blood gases and haematocrit values undergoing percutaneous nephrolithotomy if they especially have the renal and metabolic disorder.

Keywords: Nephrostomy, percutaneous; acid-base equilibrium; ırrigation

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