Turkiye Klinikleri Journal of Dental Sciences

.: ORIGINAL RESEARCH
Ön Açık ve Tam Akrilik Kaplı Hızlı Üst Çene Genişletme Apareylerinin Dental ve İskeletsel Yapılar Üzerine Etkisinin Karşılaştırılması: Retrospektif Kohort Çalışması
Comparison of the Effect of Open Front and Full Coverage Rapid Maxillary Expansion Appliances on Dental and Skeletal Structures: A Retrospective Cohort Study
Gökhan ÇOBANa , Merve Ece ERDEMa , Yunus Emre UÇAKERa , Celal IRGINa , Taner ÖZTÜRKa
aErciyes Üniversitesi Diş Hekimliği Fakültesi, Ortodonti AD, Kayseri, Türkiye
Turkiye Klinikleri J Dental Sci. 2024;30(2):256-66
doi: 10.5336/dentalsci.2023-98387
Article Language: TR
Full Text
ÖZET
 Amaç: Bu retrospektif çalışmanın amacı, büyüme-gelişimi devam etmekte olan tek ya da çift taraflı üst çene darlığına sahip hastaların, iki farklı tip hızlı üst çene genişletme (HÜÇG) apareyi ile tedavileri sonucunda dental ve iskeletsel yapılarında meydana gelen sefalometrik değişimlerin değerlendirilmesidir. Gereç ve Yöntemler: Çalışmaya tek veya çift taraflı üst çene darlığı bulunan, ön açık hızlı üst çene apareyi ile tedavi görmüş 15 (8 kadın ve 7 erkek, ortalama yaş: 15,08±1,33 yıl) hasta ve tam akrilik kaplı HÜÇG apareyi ile tedavi görmüş 15 (10 kadın ve 5 erkek, ortalama yaş: 15,79±1,42 yıl) hasta olmak üzere toplam 30 adölesan birey dâhil edilmiştir. Bireylere ait sefalometrik analizler Dolphin sefalometrik görüntüleme yazılımı kullanılarak gerçekleştirilmiştir. Verilerin grup içi karşılaştırılmasında bağımlı örneklem t-testi ve Wilcoxon Signed-Rank testi; gruplar arası karşılaştırmada ise bağımsız örneklem t-testi ve Mann-Whitney U kullanılmıştır. İstatistiksel anlamlılık değeri p<0,05 olarak kabul edilmiştir. Bulgular: Ön açık HÜÇG apareyi uygulanan grupta tedavi sonunda ANB ve SN-GoGn açıları anlamlı şekilde artarken U1/SN açısı anlamlı şekilde azalmıştır. Tam akrilik kaplı HÜÇG apareyi uygulanan grupta ise tedavi sonunda SNB ve N-Pog değerleri anlamlı derecede azalırken; ANB, SN/GoGn, L1/NB ve L1-NB değerleri anlamlı derecede artmıştır. İki grup arasında tedavi sonucunda meydana gelen değişiklikler kıyaslandığında anlamlı bir farklılık olmadığı tespit edilmiştir. Sonuç: Farklı aparey tipleri ile gerçekleştirilen HÜÇG'sinde meydana gelen sefalometrik değişikliklerin aparey tipine göre farklılık göstermediği ve her iki apareyinde benzer etkiler gösterdiği belirlenmiştir.

Anahtar Kelimeler: Damak genişletme tekniği; sefalometri; üst çene kemiği
ABSTRACT
 Objective: The aim of this retrospective study is to evaluate the cephalometric changes in dental and skeletal structures after the application of two different rapid maxillary expansion (RME) appliances in patients with uni- or bilateral maxillary crossbite whose growth-development period continues. Material and Methods: A total of 30 adolescent individuals, including 15 patients with unilateral or bilateral maxillary crossbite who were treated with Open front (8-females and 7-males, 15.08±1.33 years) and 15 patients treated with full coverage RME (10-females and 5-males, 15.79±1.42 years) appliances, were included in the study. Cephalometric analyzes of individuals were performed with Dolphin cephalometric imaging software. Paired samples-t and Wilcoxon Signed-Rank tests were used to compare data within groups, while Mann-Whitney U and Independent Samples-t tests were used for intergroup comparisons. Statistical significance value was accepted as p<0.05. Results: At the end of the treatment, in the group where the Open front appliance was applied, the ANB and SNGoGn angles increased significantly, while the U1/SN angle decreased significantly. In the group where fully coverage RME appliance was applied, SNB and N-Pog values decreased significantly at the end of the treatment; ANB, SN/GoGn, L1/NB and L1-NB values increased significantly. When the changes occurring as a result of treatment were compared between the two groups, it was determined that there was no significant difference. Conclusion: It has been determined that the cephalometric changes occurring in maxillary expansion performed with different appliance types do not differ according to the appliance type and that both appliances show similar effects.

Keywords: Palatal expansion technique; cephalometry; maxillae
REFERENCES:
  1. Çoban G, Türker G, Öztürk T, Hashimli N, Göksu M, Avcı ÖF. Ortodontik malokluzyonlarin orta anadolu bölgesinde yaşayan bireylerdeki prevelanslarinin ve karakteristiklerinin incelenmesi [Evaluation of prevalence and characteristics of orthodontic malocclusions in individuals in central anatolia]. Sağlık Bilimleri Dergisi. 2022;31(1):15-23. [Crossref] 
  2. Yavuz İ, Çakmak G. Maksiller darlik ve mandibular asimetrinin teşhis yöntemleri [Diagnostic methods of maxillary transversal deficiency and mandibular asymmetry]. Sağlık Bilimleri Dergisi. 2017;26(2):169-74. [Link] 
  3. Halicioglu K, Kiki A, Yavuz İ. Hızlı üst çene genişletmesinin tıbbi faydaları: literatür derlemesi [Medical profits of the rapid maxillary expansion: literature review]. Cumhuriyet Dental Journal. 2011;14(3):258-63. [Link] 
  4. Işeri H, Tekkaya AE, Oztan O, Bilgiç S. Biomechanical effects of rapid maxillary expansion on the craniofacial skeleton, studied by the finite element method. Eur J Orthod. 1998;20(4):347-56. [Crossref]  [PubMed] 
  5. Wertz RA. Skeletal and dental changes accompanying rapid midpalatal suture opening. Am J Orthod. 1970;58(1):41-66. [Crossref]  [PubMed] 
  6. Basciftci FA, Karaman AI. Effects of a modified acrylic bonded rapid maxillary expansion appliance and vertical chin cap on dentofacial structures. Angle Orthod. 2002;72(1):61-71. [PubMed] 
  7. Haas AJ. Rapid expansion of the maxillary dental arch and nasal cavity by opening the midpalatal suture. Angle Orthodontics 1961;31(2):73-90. [Link] 
  8. Haas AJ. The treatment of maxillary deficiency by opening the midpalatal suture. Angle Orthod. 1965;35:200-17. [PubMed] 
  9. Haas AJ. Palatal expansion: just the beginning of dentofacial orthopedics. Am J Orthod. 1970;57(3):219-55. [Crossref]  [PubMed] 
  10. Erverdi N, Sabri A, Küçükkeleş N. Cephalometric evaluation of Haas and Hyrax rapid maxillary appliances in the treatment of the skeletal maxillary transverse deficiency. J Marmara Univ Dent Fac. 1993;1(4):361-6. [PubMed] 
  11. Bishara SE, Staley RN. Maxillary expansion: clinical implications. Am J Orthod Dentofacial Orthop. 1987;91(1):3-14. [Crossref]  [PubMed] 
  12. Hicks EP. Slow maxillary expansion. A clinical study of the skeletal versus dental response to low-magnitude force. Am J Orthod. 1978;73(2):121-41. [PubMed] 
  13. McNamara JA Jr, Baccetti T, Franchi L, Herberger TA. Rapid maxillary expansion followed by fixed appliances: a long-term evaluation of changes in arch dimensions. Angle Orthod. 2003;73(4):344-53. [PubMed] 
  14. Ugolini A, Cossellu G, Rusconi FME, De Luca SD. Analysis of the palatal rugae following Rapid Maxillary Expansion (RME) by using a 3D-3D superimposition procedure. Australian Journal of Forensic Sciences. 2023;55(2):191-202. [Crossref] 
  15. Ramoglu SI, Sari Z. Maxillary expansion in the mixed dentition: rapid or semi-rapid? Eur J Orthod. 2010;32(1):11-8. [Crossref]  [PubMed] 
  16. Brennan J. An introduction to digital radiography in dentistry. J Orthod. 2002;29(1):66-9. [Crossref]  [PubMed] 
  17. Gupta A. On imaging modalities for cephalometric analysis: a review. Multimedia Tools and Applications. 2023;82(24):36837-58. [Crossref] 
  18. Karaman A, Danisman H, Genc E, Buyuk SK. Comparison of skeletal and dental effects of two different tooth-tissue-borne types of rapid maxillary expansion appliances: a CBCT retrospective study. Orthod Craniofac Res. 2023;26(1):123-31. [Crossref]  [PubMed] 
  19. Lagravere MO, Major PW, Flores-Mir C. Long-term skeletal changes with rapid maxillary expansion: a systematic review. Angle Orthod. 2005;75(6):1046-52. [PubMed] 
  20. Agarwal A, Mathur R. Maxillary Expansion. Int J Clin Pediatr Dent. 2010;3(3):139-46. [Crossref]  [PubMed]  [PMC] 
  21. Akkaya S, Lorenzon S, Uçem TT. A comparison of sagittal and vertical effects between bonded rapid and slow maxillary expansion procedures. Eur J Orthod. 1999;21(2):175-80. [Crossref]  [PubMed] 
  22. McNamara JA. Maxillary transverse deficiency. Am J Orthod Dentofacial Orthop. 2000;117(5):567-70. [Crossref]  [PubMed] 
  23. Mommaerts MY. Transpalatal distraction as a method of maxillary expansion. Br J Oral Maxillofac Surg. 1999;37(4):268-72. [Crossref]  [PubMed] 
  24. Orhan M, Üsümez S, Malkoc S. Modified bonded rapid maxillary expansion appliance. World Journal of Orthodontics. 2003;4(2):119-25. [Link] 
  25. Gül Amuk N, Kurt G. Ortognatik cerrahi planlamasinda okluzal düzlem değerlendirmesinin önemi [Evaluation of occlusal plane in orthognathic surgery planning]. Turkiye Klinikleri J Oral Maxillofac Surg-Special Topics. 2017;3(3):93-101. [Link] 
  26. Alpern MC, Yurosko JJ. Rapid palatal expansion in adults with and without surgery. Angle Orthod. 1987;57(3):245-63. [PubMed] 
  27. Lima AC, Lima AL, Filho RM, Oyen OJ. Spontaneous mandibular arch response after rapid palatal expansion: a long-term study on Class I malocclusion. Am J Orthod Dentofacial Orthop. 2004;126(5):576-82. [Crossref]  [PubMed] 
  28. Da Silva Filho OG, Garib D, Ribeiro GU, Cruz RM. Interview-Eric Liou. R Dent Press Ortodon Ortop Facial. 2009;14(5):27-37. [Crossref] 
  29. Farronato G, Giannini L, Galbiati G, Maspero C. Sagittal and vertical effects of rapid maxillary expansion in Class I, II, and III occlusions. Angle Orthod. 2011;81(2):298-303. [Crossref]  [PubMed]  [PMC] 
  30. Stuart DA, Wiltshire WA. Rapid palatal expansion in the young adult: time for a paradigm shift? J Can Dent Assoc. 2003;69(6):374-7. [PubMed] 
  31. dos Santos BM, Stuani AS, Stuani AS, Faria G, Quintão CC, Stuani MB. Soft tissue profile changes after rapid maxillary expansion with a bonded expander. Eur J Orthod. 2012;34(3):367-73. [Crossref]  [PubMed] 
  32. Sari Z, Uysal T, Usumez S, Basciftci FA. Rapid maxillary expansion. Is it better in the mixed or in the permanent dentition? Angle Orthod. 2003;73(6):654-61. [PubMed] 
  33. Wendling LK, McNamara JA Jr, Franchi L, Baccetti T. A prospective study of the short-term treatment effects of the acrylic-splint rapid maxillary expander combined with the lower Schwarz appliance. Angle Orthod. 2005;75(1):7-14. [PubMed] 
  34. Lee HK, Bayome M, Ahn CS, Kim SH, Kim KB, Mo SS, et al. Stress distribution and displacement by different bone-borne palatal expanders with micro-implants: a three-dimensional finite-element analysis. Eur J Orthod. 2014;36(5):531-40. [Crossref]  [PubMed] 

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