Turkiye Klinikleri Journal of Dental Sciences

.: ORIGINAL RESEARCH
Kalsiyum Silikat İçerikli Pulpa Kapaklama Materyallerinin Farklı Adeziv Sistemler ile Kompozit Rezinlere Makaslama Bağlanma Dayanımı: İn Vitro Çalışma
Shear Bond Strength of Calcium Silicate-Based Pulp Capping Materials to Composite Resins with Different Adhesive Systems: In Vitro Study
Gülşah TONGAa, Emine ŞİRİN KARAARSLANb, Hüseyin HATIRLIa
aTokat Gaziosmanpaşa Üniversitesi Diş Hekimliği Fakültesi, Restoratif Diş Tedavisi ABD, Tokat, Türkiye
bSerbest Hekim, Gaziantep, Türkiye
Turkiye Klinikleri J Dental Sci. 2022;28(3):673-81
doi: 10.5336/dentalsci.2021-86153
Article Language: TR
Full Text
ÖZET
 Amaç: Bu çalışmanın amacı, kalsiyum silikat içerikli pulpa kapaklama materyallerinin farklı adeziv sistemler kullanılarak kompozit rezinlere makaslama bağlanma dayanımını değerlendirmektir. Gereç ve Yöntemler: Yüz seksen adet merkezinde boşluk olan akrilik rezin blok hazırlandı. Akrilik rezin bloklar 3 gruba ayrıldı ve kalsiyum silikat içerikli materyallerden (ProRoot MTA, Biodentin, TheraCal LC) biri ile dolduruldu. Bu örnekler daha sonra kullanılan adeziv sistem (total-etch, 2 aşamalı self-etch ve üniversal adeziv) ve kompozit rezinlere (6 grup, n=10) göre alt gruplara ayrıldı. Adeziv sistemler uygulandı ve üniversal (Estelite Sigma Quick, Tokuyama) veya akışkan kompozit rezin (Estelite Universal Flow, Tokuyama) tabakalı olarak yerleştirildi ve 20 sn ışıkla sertleştirildi. Daha sonra tüm örnekler 5.000 termal döngü ile yaşlandırmaya tabi tutuldu. Numuneler daha sonra üniversal test cihazı kullanılarak makaslama bağlanma dayanımı açısından değerlendirildi. Bulgular: Üç-yönlü ANOVA sonuçları, totaletch adeziv ile üniversal kompozit rezine bağlanan ProRoot MTA'nın en yüksek makaslama bağlanma kuvvetine sahip olduğunu ve en düşük makaslama bağlanma kuvveti değerinin 2 aşamalı self-ech adeziv ile üniversal kompozite bağlanan TheraCal LC'de gözlendi (p<0,05). Sonuç: Termal yaşlandırma sonrasında TheraCal LC gruplarında çoğunlukla koheziv kırılma görüldü. Biodentin ve MTA ile karşılaştırıldığında, TheraCal LC total-etch ve 2 aşamalı self-etch adeziv kullanılarak üniversal kompozit rezine bağlanan gruplarda daha fazla makaslama bağlanma dayanımı değerleri daha düşüktü.

Anahtar Kelimeler: Dental pulpa kapaklama; mineral trioksit agregat; kalsiyum silikat
ABSTRACT
 Objective: The aim of this study was to evaluate the shear bond strength of calcium silicate-based pulp capping materials bonded to composite resins with different adhesive systems. Material and Methods: A total of 180 acrylic resin blocks were prepared with a central hole. Acrylic resin blocks were divided into three groups and each group filled with one of the three calcium silicate-based materials (ProRoot MTA, Biodentine, TheraCal LC). These samples were then subdivided according to the adhesive systems (total-etch, 2 step selfetch, and universal adhesive) and composite resins used (6 groups, n=10). Adhesive systems were applied and universal (Estelite Sigma Quick, Tokuyama) or flowable (Estelite Universal Flow, Tokuyama) composite resin was placed incrementally and light-cured for 20 s. After that, all specimens were subjected to 5,000 thermal aging cycles. The specimens were then evaluated for shear bond strength using a universal testing machine. Results: Three-way ANOVA results revealed that the ProRoot MTA bonded to the universal composite resin with a totaletch adhesive had the highest shear bond strength, and the lowest mean shear bond strength value was observed in the TheraCal LC bonded to the universal composite resin with a two-step self-etch adhesive (p<0.05). Conclusion: TheraCal LC groups showed mainly cohesive fracture after thermal aging. Shear bond strength values were lower in groups bonded to the universal composite resin using TheraCal LC with total-etch and two-step self-etch adhesive compared to Biodentine and ProRoot MTA.

Keywords: Dental pulp capping; mineral trioxide aggregate; calcium silicate
REFERENCES:
  1. Hargreaves KM, Goodis HE, Tay FR. Seltzer and Bender's Dental Pulp. 2nd ed. Hanover Park, IL: Quintessence Pub.; 2012.
  2. Hilton TJ. Keys to clinical success with pulp capping: a review of the literature. Oper Dent. 2009;34(5):615-25. [Crossref]  [PubMed]  [PMC] 
  3. Tziafas D, Smith AJ, Lesot H. Designing new treatment strategies in vital pulp therapy. J Dent. 2000;28(2):77-92. [Crossref]  [PubMed] 
  4. Kopel HM. Considerations for the direct pulp capping procedure in primary teeth: a review of the literature. ASDC J Dent Child. 1992; 59(2):141-9. [PubMed] 
  5. Hilton TJ, Ferracane JL, Mancl L; Northwest Practice-based Research Collaborative in Evidence-based Dentistry (NWP). Comparison of CaOH with MTA for direct pulp capping: a PBRN randomized clinical trial. J Dent Res. 2013;92(7 Suppl):16S-22S. [Crossref]  [PubMed]  [PMC] 
  6. de Souza Costa CA, Duarte PT, de Souza PP, Giro EM, Hebling J. Cytotoxic effects and pulpal response caused by a mineral trioxide aggregate formulation and calcium hydroxide. Am J Dent. 2008;21(4):255-61. [PubMed] 
  7. Briso AL, Rahal V, Mestrener SR, Dezan Junior E. Biological response of pulps submitted to different capping materials. Braz Oral Res. 2006;20(3):219-25. [Crossref]  [PubMed] 
  8. Parirokh M, Torabinejad M, Dummer PMH. Mineral trioxide aggregate and other bioactive endodontic cements: an updated overview-part I: vital pulp therapy. Int Endod J. 2018;51(2):177-205. [Crossref]  [PubMed] 
  9. Giraud T, Jeanneau C, Rombouts C, Bakhtiar H, Laurent P, About I. Pulp capping materials modulate the balance between inflammation and regeneration. Dent Mater. 2019;35(1):24-35. [Crossref]  [PubMed] 
  10. Camilleri J, Laurent P, About I. Hydration of Biodentine, Theracal LC, and a prototype tricalcium silicate-based dentin replacement material after pulp capping in entire tooth cultures. J Endod. 2014;40(11):1846-54. [Crossref]  [PubMed] 
  11. Makkar S, Vashisht R, Kalsi A, Gupta P. The effect of altered ph on push-out bond strength of biodentin, glass ionomer cement, mineral trioxide aggregate and theracal. Stomatol Glas Srb. 2015;62(1):7-13. [Crossref] 
  12. Macwan C, Deshpande A. Mineral trioxide aggregate (MTA) in dentistry: a review of literature. J Oral Res. 2014;6(2):71-4. [Crossref] 
  13. Dammaschke T. A new bioactive cement for direct pulp capping. Int Dent. 2012;7:52-8. [Link] 
  14. Dawood AE, Parashos P, Wong RHK, Reynolds EC, Manton DJ. Calcium silicate-based cements: composition, properties, and clinical applications. J Investig Clin Dent. 2017;8(2). [Crossref]  [PubMed] 
  15. Giraud T, Jeanneau C, Bergmann M, Laurent P, About I. Tricalcium silicate capping materials modulate pulp healing and inflammatory activity in vitro. J Endod. 2018;44(11):1686-91. [Crossref]  [PubMed] 
  16. Jeanneau C, Laurent P, Rombouts C, Giraud T, About I. Light-cured tricalcium silicate toxicity to the dental pulp. J Endod. 2017;43(12):2074-80. [Crossref]  [PubMed] 
  17. Tunç ES, Sönmez IS, Bayrak S, Eğilmez T. The evaluation of bond strength of a composite and a compomer to white mineral trioxide aggregate with two different bonding systems. J Endod. 2008;34(5):603-5. [Crossref]  [PubMed] 
  18. Alzraikat H, Taha NA, Qasrawi D, Burrow MF. Shear bond strength of a novel light cured calcium silicate based-cement to resin composite using different adhesive systems. Dent Mater J. 2016;35(6):881-7. [Crossref]  [PubMed] 
  19. Karadas M, Cantekin K, Gumus H, Ateş SM, Duymuş ZY. Evaluation of the bond strength of different adhesive agents to a resin-modified calcium silicate material (TheraCal LC). Scanning. 2016;38(5):403-11. [Crossref]  [PubMed] 
  20. Woronko GA Jr, St Germain HA Jr, Meiers JC. Effect of dentin primer on the shear bond strength between composite resin and ena mel. Oper Dent. 1996;21(3):116-21. [PubMed] 
  21. Stanley HR. Pulp capping: conserving the dental pulp--can it be done? Is it worth it? Oral Surg Oral Med Oral Pathol. 1989;68(5):628-39. [Crossref]  [PubMed] 
  22. Raina A, Sawhny A, Paul S, Nandamuri S. Comparative evaluation of the bond strength of self-adhering and bulk-fill flowable composites to MTA Plus, Dycal, Biodentine, and TheraCal: an in vitro study. Restor Dent Endod. 2020;45(1):e10. [Crossref]  [PubMed]  [PMC] 
  23. Akbiyik SY, Bakir EP, Bakir Se. Evaluation of the bond strength of different pulp capping materials to dental adhesive systems: an in vitro study. J Adv Oral Res. 2021:12(2). [Crossref] 
  24. Sismanoglu S, Yildirim-Bilmez Z, Gurcan A, Gumustas B. Influence of application mode of universal adhesive on the surface morphology, elemental composition and bond strength of calcium silicate-based cements to composite resin: a SEM-EDX microanalysis study. J Adhes Sci Technol. 2021:1-14. [Crossref] 
  25. Buldur B, Öznurhan F, Kayabaşı M, Şahin F. Shear bond strength of two calcium silicate-based cements to compomer. Cumhur Dent J. 2018;21(1):18-23. [Crossref] 
  26. Savadi Oskoee S, Bahari M, Kimyai S, Motahhari P, Eghbal MJ, Asgary S. Shear bond strength of calcium enriched mixture cement and mineral trioxide aggregate to composite resin with two different adhesive systems. J Dent (Tehran). 2014;11(6):665-71. [PubMed]  [PMC] 
  27. Cantekin K, Avci S. Evaluation of shear bond strength of two resin-based composites and glass ionomer cement to pure tricalcium silicate-based cement (Biodentine®). J Appl Oral Sci. 2014;22(4):302-6. [Crossref]  [PubMed]  [PMC] 
  28. Atabek D, Sillelioğlu H, Olmez A. Bond strength of adhesive systems to mineral trioxide aggregate with different time intervals. J Endod. 2012;38(9):1288-92. [Crossref]  [PubMed] 
  29. Bachoo IK, Seymour D, Brunton P. A biocompatible and bioactive replacement for dentine: is this a reality? The properties and uses of a novel calcium-based cement. Br Dent J. 2013;214(2):E5. [Crossref]  [PubMed] 
  30. Gandolfi MG, Taddei P, Siboni F, Modena E, Ciapetti G, Prati C. Development of the foremost light-curable calcium-silicate MTA cement as root-end in oral surgery. Che mical-physical properties, bioactivity and biological behavior. Dent Mater. 2011;27(7): e134-57. [Crossref]  [PubMed] 
  31. Cantekin K. Bond strength of different restorative materials to light-curable mineral trioxide aggregate. J Clin Pediatr Dent. 2015;39(2):143-8. [Crossref]  [PubMed] 
  32. Guneser MB, Akbulut MB, Eldeniz AU. Effect of various endodontic irrigants on the push-out bond strength of biodentine and conventional root perforation repair materials. J Endod. 2013;39(3):380-4. [Crossref]  [PubMed] 
  33. Pradeep P, Randhya R, Shanavas Palliyal MK, Hima S. An in vitro comparative evaluation of shear bond strength of biodentine and MTA. Int J Appl Dent Sci. 2018;4(2):01-03. [Link] 
  34. Hashem DF, Foxton R, Manoharan A, Watson TF, Banerjee A. The physical characteristics of resin composite-calcium silicate interface as part of a layered/laminate adhesive restoration. Dent Mater. 2014;30(3):343-9. [Crossref]  [PubMed] 
  35. Yoshida Y, Yoshihara K, Hayakawa S, Nagaoka N, Okihara T, et al. HEMA inhibits interfacial nano-layering of the functional monomer MDP. J Dent Res. 2012;91(11):1060-5. [Crossref]  [PubMed] 

.: Up To Date

.: Process List

Login

 Forgot your password?

 New Registration  

Contact

Ortadoğu Reklam Tanıtım Yayıncılık Turizm Eğitim İnşaat Sanayi ve Ticaret A.Ş.

.: Address

Turkocagi Caddesi No:30 06520 Balgat / ANKARA
Phone: +90 312 286 56 56
Fax: +90 312 220 04 70
E-mail: info@turkiyeklinikleri.com

.: Manuscript Editing Department

Phone: +90 312 286 56 56/ 2
E-mail: yaziisleri@turkiyeklinikleri.com

.: English Language Redaction

Phone: +90 312 286 56 56/ 145
E-mail: tkyayindestek@turkiyeklinikleri.com

.: Marketing Sales-Project Department

Phone: +90 312 286 56 56/ 142
E-mail: reklam@turkiyeklinikleri.com

.: Subscription and Public Relations Department

Phone: +90 312 286 56 56/ 118
E-mail: abone@turkiyeklinikleri.com

.: Customer Services

Phone: +90 312 286 56 56/ 118
E-mail: satisdestek@turkiyeklinikleri.com

1. TERMS OF USE

1.1. To use the web pages with http://www.turkiyeklinikleri.com domain name or the websites reached through the sub domain names attached to the domain name (They will be collectively referred as "SITE"), please read the conditions below. If you do not accept these terms, please cease to use the "SITE." "SITE" owner reserves the right to change the information on the website, forms, contents, the "SITE," "SITE" terms of use anytime they want.

1.2. The owner of the "SITE" is Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. (From now on it is going to be referred as "Turkiye Klinikleri", shortly) and it resides at Turkocagi cad. No:30, 06520 Balgat Ankara. The services in the "SITE" are provided by "Turkiye Klinikleri."

1.3. Anyone accessing the "SITE" with or without a fee whether they are a natural person or a legal identity is considered to agree these terms of use. In this contract hereby, "Turkiye Klinikleri" may change the stated terms anytime. These changes will be published in the "SITE" periodically and they will be valid when they are published. Any natural person or legal identity benefiting from and reaching to the "SITE" are considered to be agreed to any change on hereby contract terms done by "Turkiye Klinikleri."

1.4. The "Terms of Use" hereby is published in the website with the last change on March 30th 2014 and the "SITE" is activated by enabling the access to everyone. The "Terms of Use" hereby is also a part of the any "USER Contract" was and/or will be done with the users using "Turkiye Klinikleri" services with or without a fee an inseparable.

2. DEFINITIONS

2.1. "SITE": A website offering different kind of services and context with a certain frame determined by "Turkiye Klinikleri" and it is accessible on-line on http://www.turkiyeklinikleri.com domain name and/or subdomains connected to the domain name.

2.2. USER: A natural person or a legal identity accessing to the "SITE" through online settings.

2.3. LINK: A link enabling to access to another website through the "SITE", the files, the context or through another website to the "SITE", the files and the context.

2.4. CONTEXT: Any visual, literary and auditory images published in the "Turkiye Klinikleri", "SITE" and/or any website or any accessible information, file, picture, number/figures, price, etc.

2.5. "USER CONTRACT": An electronically signed contract between a natural or a legal identity benefiting from special services "Turkiye Klinikleri" will provide and "Turkiye Klinikleri".

3. SCOPE OF THE SERVICES

3.1. "Turkiye Klinikleri" is completely free to determine the scope and quality of the services via the "SITE".

3.2. To benefit the services of "Turkiye Klinikleri" "SITE", the "USER" must deliver the features that will be specified by "Turkiye Klinikleri". "Turkiye Klinikleri" may change this necessity any time single-sided.

3.3. Not for a limited number, the services "Turkiye Klinikleri" will provide through the "SITE" for a certain price or for free are;

- Providing scientific articles, books and informative publications for health industry.

- Providing structural, statistical and editorial support to article preparation stage for scientific journals.

4. GENERAL PROVISIONS

4.1. "Turkiye Klinikleri" is completely free to determine which of the services and contents provided in the "SITE" will be charged.

4.2. People benefiting from the services provided by "Turkiye Klinikleri" and using the website can use the "SITE" only according to the law and only for personal reasons. Users have the criminal and civil liability for every process and action they take in the "SITE". Every USER agrees, declares and undertakes that they will not proceed by any function or action infringement of rights of "Turkiye Klinikleri"s and/or other third parties', they are the exclusive right holder on usage, processing, storage, made public and revealing any written, visual or auditory information reported to Turkiye Klinikleri" and/or "SITE" to the third parties. "USER" agrees and undertakes that s/he will not duplicate, copy, distribute, process, the pictures, text, visual and auditory images, video clips, files, databases, catalogs and lists within the "SITE", s/he will not be using these actions or with other ways to compete with "Turkiye Klinikleri", directly or indirectly.

4.3. The services provided and the context published within the "SITE" by third parties is not under the responsibility of "Turkiye Klinikleri", institutions collaborated with "Turkiye Klinikleri", "Turkiye Klinikleri" employee and directors, "Turkiye Klinikleri" authorized salespeople. Commitment to accuracy and legality of the published information, context, visual and auditory images provided by any third party are under the full responsibility of the third party. "Turkiye Klinikleri" does not promise and guarantee the safety, accuracy and legality of the services and context provided by a third party.

4.4. "USER"s cannot act against "Turkiye Klinikleri", other "USER"s and third parties by using the "SITE". "Turkiye Klinikleri" has no direct and/or indirect responsibility for any damage a third party suffered or will suffer regarding "USER"s actions on the "SITE" against the rules of the hereby "Terms of Use" and the law.

4.5. "USER"s accept and undertake that the information and context they provided to the "SITE" are accurate and legal. "Turkiye Klinikleri" is not liable and responsible for promising and guaranteeing the verification of the information and context transmitted to "Turkiye Klinikleri" by the "USER"s, or uploaded, changed and provided through the "SITE" by them and whether these information are safe, accurate and legal.

4.6. "USER"s agree and undertake that they will not perform any action leading to unfair competition, weakening the personal and commercial credit of "Turkiye Klinikleri" and a third party,  encroaching and attacking on personal rights within the "SITE" in accordance with the Turkish Commercial Code Law.

4.7. "Turkiye Klinikleri" reserves the right to change the services and the context within the "SITE"  anytime. "Turkiye Klinikleri" may use this right without any notification and timelessly. "USER"s have to make the changes and/or corrections "Turkiye Klinikleri" required immediately. Any changes and/or corrections that are required by "Turkiye Klinikleri", may be made by "Turkiye Klinikleri" when needed. Any harm, criminal and civil liability resulted or will result from changes and/or corrections required by "Turkiye Klinikleri" and were not made on time by the "USER"s belongs completely to the users.

4.8. "Turkiye Klinikleri" may give links through the "SITE" to other websites and/or "CONTEXT"s and/or folders that are outside of their control and owned and run by third parties. These links are provided for ease of reference only and do not hold qualification for support the respective web SITE or the admin or declaration or guarantee for the information inside. "Turkiye Klinikleri" does not hold any responsibility over the web-sites connected through the links on the "SITE", folders and context, the services or products on the websites provided through these links or their context.

4.9. "Turkiye Klinikleri" may use the information provided to them by the "USERS" through the "SITE" in line with the terms of the "PRIVACY POLICY" and "USER CONTRACT". It may process the information or classify and save them on a database. "Turkiye Klinikleri" may also use the USER's or visitor's identity, address, e-mail address, phone number, IP number, which sections of the "SITE" they visited, domain type, browser type, date and time information to provide statistical evaluation and customized services.

5. PROPRIETARY RIGHTS

5.1. The information accessed through this "SITE" or provided by the users legally and all the elements (including but not limited to design, text, image, html code and other codes) of the "SITE" (all of them will be called as studies tied to "Turkiye Klinikleri"s copyrights) belongs to "Turkiye Klinikleri". Users do not have the right to resell, process, share, distribute, display or give someone permission to access or to use the "Turkiye Klinikleri" services, "Turkiye Klinikleri" information and the products under copyright protection by "Turkiye Klinikleri". Within hereby "Terms of Use" unless explicitly permitted by "Turkiye Klinikleri" nobody can reproduce, process, distribute or produce or prepare any study from those under "Turkiye Klinikleri" copyright protection.

5.2. Within hereby "Terms of Use", "Turkiye Klinikleri" reserves the rights for "Turkiye Klinikleri" services, "Turkiye Klinikleri" information, the products associated with "Turkiye Klinikleri" copyrights, "Turkiye Klinikleri" trademarks, "Turkiye Klinikleri" trade looks or its all rights for other entity and information it has through this website unless it is explicitly authorized by "Turkiye Klinikleri".

6. CHANGES IN THE TERMS OF USE

"Turkiye Klinikleri" in its sole discretion may change the hereby "Terms of Use" anytime announcing within the "SITE". The changed terms of the hereby "Terms of Use" will become valid when they are announced. Hereby "Terms of Use" cannot be changed by unilateral declarations of users.

7. FORCE MAJEURE

"Turkiye Klinikleri" is not responsible for executing late or never of this hereby "Terms of Use", privacy policy and "USER Contract" in any situation legally taken into account as force majeure. Being late or failure of performance or non-defaulting of this and similar cases like this will not be the case from the viewpoint of "Turkiye Klinikleri", and "Turkiye Klinikleri" will not have any damage liability for these situations. "Force majeure" term will be regarded as outside of the concerned party's reasonable control and any situation that "Turkiye Klinikleri" cannot prevent even though it shows due diligence. Also, force majeure situations include but not limited to natural disasters, rebellion, war, strike, communication problems, infrastructure and internet failure, power cut and bad weather conditions.

8. LAW AND AUTHORISATION TO FOLLOW

Turkish Law will be applied in practicing, interpreting the hereby "Terms of Use" and managing the emerging legal relationships within this "Terms of Use" in case of finding element of foreignness, except for the rules of Turkish conflict of laws. Ankara Courts and Enforcement Offices are entitled in any controversy happened or may happen due to hereby contract.

9. CLOSING AND AGREEMENT

Hereby "Terms of Use" come into force when announced in the "SITE" by "Turkiye Klinikleri". The users are regarded to agree to hereby contract terms by using the "SITE". "Turkiye Klinikleri" may change the contract terms and the changes will be come into force by specifying the version number and the date of change on time it is published in the "SITE".

 

30.03.2014

Privacy Policy

We recommend you to read the terms of use below before you visit our website. In case you agree these terms, following our rules will be to your favor. Please read our Terms of Use thoroughly.

www.turkiyeklinikleri.com website belongs to Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. and is designed in order to inform physicians in the field of health

www.turkiyeklinikleri.com cannot reach to user’s identity, address, service providers or other information. The users may send this information to the website through forms if they would like to. However, www.turkiyeklinikleri.com may collect your hardware and software information. The information consists of your IP address, browser type, operating system, domain name, access time, and related websites. www.turkiyeklinikleri.com cannot sell the provided user information (your name, e-mail address, home and work address, phone number) to the third parties, publish it publicly, or keep it in the website. Gathered information has a directing feature to be a source for the website’s visitor profile, reporting and promotion of the services.

www.turkiyeklinikleri.com uses the taken information:

-To enhance, improve and maintain the quality of the website

-To generate visitor’s profile and statistical data

-To determine the tendency of the visitors on using our website

-To send print publications/correspondences

-To send press releases or notifications through e-mail

-To generate a list for an event or competition

By using www.turkiyeklinikleri.com you are considered to agree that;

-Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. cannot be hold responsible for any user’s illegal and immoral behavior,

-Terms of use may change from time to time,

-It is not responsible for other websites’ contents it cannot control or the harms they may cause although it uses the connection they provided.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. may block the website to users in the following events:

-Information with wrong, incomplete, deceiving or immoral expressions is recorded to the website,

-Proclamation, advertisement, announcement, libelous expressions are used against natural person or legal identity,

-During various attacks to the website,

-Disruption of the website because of a virus.

Written, visual and audible materials of the website, including the code and the software are under protection by legal legislation.

Without the written consent of Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. the information on the website cannot be downloaded, changed, reproduced, copied, republished, posted or distributed.

All rights of the software and the design of the website belong to Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. will be pleased to hear your comments about our terms of use. Please share the subjects you think may enrich our website or if there is any problem regarding our website.

info@turkiyeklinikleri.com