Amaç: Bu çalışma, ilk banyoda kullanılan temizleme ürününün ve suyun geç preterm ve term yenidoğanların cilt bariyerlerine etkisini değerlendirmek amacıyla yapılmıştır. Gereç ve Yöntemler: Araştırma çok merkezli, tek kör, randomize kontrollü çalışmadır. Araştırma Eylül 2021-Eylül 2022 arasında Türkiye'de bir üniversite hastanesi ve iki devlet hastanesinin yenidoğan yoğun bakım ünitelerinde gerçekleştirildi. Gestasyon yaşları 34 0/7 hafta ile 41 6/7 hafta arasındaki yenidoğanlar, girişim (n=60) veya kontrol grubuna (n=60) rastgele atandı. Girişim grubundaki bebeklerin ilk banyoları, bir temizleme ürünü kullanılarak gerçekleştirildi. Kontrol grubundaki bebekler, ilk banyolarında sadece su ile yıkandı. Bebeklerin transepidermal su kaybı (TESK) ve cilt pH'ı banyodan önce, banyo başladıktan 10. ve 30. dk'larda ölçüldü. Bulgular: Araştırma toplam 120 bebek ile tamamlandı. Gruplara ve zamana göre TESK ve cilt pH'sı açısından istatistiksel olarak anlamlı bir fark yoktu (p>0,05). Girişim grubu, takip sırasında ön kolda (p=0,369; β=-2,20, 0,40) ve sternumda (p=0,154; β=-2,92, 0,60) kontrol grubuna göre benzer bir TESK değerine sahipti. Kontrol grubunun ortalama cilt pH değeri (p=0,369; β=-0,78, -0,43) girişim grubu ile benzerlik gösterdi. Sonuç: Bu araştırmada, geç preterm ve term yenidoğanların ilk banyosunda kullanılan temizleme ürününün sadece su ile yapılan banyodan farklı bir cilt bariyer etkisi olmadığı ortaya konulmuştur. Bu nedenle ilk banyoda, kolay ulaşılabilir ve masrafsız olan su ile yıkama tercih edilebilir veya doğru seçilmiş bir temizleme ürünü yenidoğanın ilk banyosunda güvenle kullanılabilir.
Anahtar Kelimeler: Cilt bariyeri; erken doğmuş bebek; ilk banyo; temizleme ürünü; transepidermal su kaybı
Objective: This study was conducted to evaluate the effect of the cleaning product and water used in the first bath on the skin barriers of late preterm and term infants. Material and Methods: The research is a multicenter, single-blind, randomized controlled study. The research was conducted between September 2021 and September 2022 in the neonatal intensive care units of a university hospital and two state hospitals in Türkiye. Infants with gestational ages between 34 0/7 weeks and 41 6/7 weeks were randomly assigned to the intervention (n=60) or control group (n=60). The first baths of infants in the intervention group were performed using a cleaning product. Infants in the control group were bathed with only water in their first bath. Transepidermal water loss (TEWL) and skin pH of the infants were measured before the bath and at the 10th and 30th minutes after the bath started. Results: The research was completed with a total of 120 infants. There was no statistically significant difference in TEWL and skin pH according to groups and time (p>0.05). The intervention group had a similar TEWL value to the control group at follow-up at the forearm (p=0.369; β=-2.20, 0.40) and sternum (p=0.154; β=-2.92, 0.60). The mean skin pH value of the control group (p=0.369; β=-0.78, -0.43) was similar to the intervention group. Conclusion: This study found that using a cleaning product during the first bath of late preterm and term newborns does not affect the skin barrier differently compared to bathing with water alone. Therefore, for the first bath, it is suggested to use easily accessible and inexpensive water, or if preferred, a suitable cleaning product can be safely used.
Keywords: Skin barrier; preterm infant; first bath; cleaning product; transepidermal water loss
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