Turkiye Klinikleri Journal of Dermatology

.: ORIGINAL RESEARCH
Hidradenitis Suppurativa: A 9-Year Retrospective Study from Malatya, Turkey
Hidradenitis Süpürativa: Türkiye Malatya'dan 9 Yıllık Retrospektif Bir Çalışma
Nihal ALTUNIŞIKa, Serpil ŞENERa
aDepartment of Dermatology, İnonu University Faculty of Medicine, Malatya, TURKEY
Turkiye Klinikleri J Dermatol. 2019;29(2):69-74
doi: 10.5336/dermato.2019-66868
Article Language: EN
Full Text
ABSTRACT
 Objective: Hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory skin disease. Our aim of this study is to review the demographic, clinical characteristics, treatment options of the patients who were being followed up with diagnosis of HS in our hospital during the last 9 years and to make a comparison with the data from other countries. Material and Methods: A total of 59 patients with HS diagnosed in our Dermatology Department between 2010-2019 were evaluated retrospectively. Results: Seventeen (28.8%) of 59 patients were female, 42 (71.2%) were male. The mean age at diagnosis was 31.05±1.61 (minimum / maximum: 14-60). Seventeen patients (28.8%) had stage 1, 26 patients (44.1%) had stage 2 and 16 patients (27.1%) had stage 3 disease. Axilla was the most affected area. Topical agents (topical clindamycin, antiseptic solutions) and oral antibiotics (doxycycline, ciprof loxacin, ampicillin-sulbactam, amoxicillin-clavulanic acid) were the most commonly used treatment options. Treatment resistant eight patients were treated with a biological agent adalimumab. Conclusion: In literature, there are few epidemiological studies related to HS in Turkey. The clinical, demographic and therapeutic data of 59 HS cases in our clinic were summarized. However, we believe that multi-center studies conducted with larger number of patients are needed in order to reach more comprehensive data on this subject.

Keywords: Hidradenitis suppurativa; hidradenitis; disease management
ÖZET
 Amaç: Hidradenitis süpürativa (HS) kronik, tekrarlayan inflamatuar bir cilt hastalığıdır. Bu çalışmada amacımız, son 9 yılda hastanemizde HS tanısı ile takip edilen hastaların demografik, klinik özellikleri, tercih edilen tedavi seçeneklerini gözden geçirmek ve diğer ülkelerdeki verilerle karşılaştırmaktır. Gereç ve Yöntemler: Çalışmamızda 2010-2019 yılları arasında Dermatoloji kliniğinde tanı koyulan 59 HS hastası retrospektif olarak değerlendirildi. Bulgular: Elli dokuz hastanın 17'si (%28,8) kadın, 42'si (%71,2) erkekti. Hastaların tanı sırasındaki yaş ortalaması 31,05±1,61 (minimum/ maksimum: 14-60) idi. Hastalardan 17'si (%28,8) evre 1,26'sı (%44,1) evre 2,16'sı (%27,1) evre 3 olarak değerlendirildi. Aksilla en fazla etkilenen bölgeydi. Topikal ajanlar (topikal klindamisin, antiseptik solüsyonlar) ve oral antibiyotikler (doksisiklin, siprofloksasin, ampisilin-sulbaktam, amoksisilin-klavulanik asit) en sık kullanılan tedavi seçenekleriydi. Tedaviye dirençli 8 hasta biyolojik ajanlardan adalimumab ile tedavi edildi. Sonuç: Literatürde, Türkiye'de HS ile ilgili yapılan az sayıda epidemiyolojik çalışma bulunmaktadır. Kliniğimizde takip edilen 59 HS vakasının klinik, demografik ve terapötik verileri özetlendi. Ancak, bu konuda daha kapsamlı verilere ulaşmak için çok merkezli ve daha fazla vaka içeren çalışmalara ihtiyaç olduğuna inanıyoruz.

Anahtar Kelimeler: Hidradenitis süpürativa; hidradenit; hastalık yönetimi
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