Turkiye Klinikleri Journal of Medical Sciences

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Hemisferik Asimetri: Tek Yanlı Uyarı,Bilateral Elektrodermal Aktivite
HEMISPHERIC ASYMMETRY: UNILATERAL STIMULATION,BILATERAL ELECTRODERMAL ACTIVITY
Ferhan ESEN*
*, Osmangazi Üniversitesi Tıp Fakültesi Biyofizik AD, ESKİŞEHİR
Turkiye Klinikleri J Med Sci. 2002;22(1):82-6
Article Language: TR
Full Text
ÖZET
Beynin lateralitesi ile ilgili çalışmalar sağ ve sol hemisferler arasında fonksiyonel farklılık olduğu düşüncesini destekler nitelikte olup otonom sinir sisteminin bir bileşeni olan elektrodermal aktivitenin (EDA) de lateralize olabileceğini düşündürmektedir. Bu nedenle, bu çalışmada palmar EDA'nın bilateral asimetri gösteren parametrelerini ortaya koymak ve bu parametrelerin bağıl hemisferik aktivasyonun göstergesi olarak yararlılığını değerlendirmek üzere tercihli olarak sağ elini kullanan 25 erkekte deri direnç düzeyi (SRL), deri direnç yanıtı (SRR) ve SRR latansı (L) incelenmiştir. Çalışmada, EDA değişkenlerinin uyarı bölgesi ve el tercihi ile ilişkili asimetrilerini belirlemede tek yanlı uyarı (klik şeklinde işitsel / patella tendonuna mekanik) ile çift yanlı kayıtlama yapılmıştır. Elektrodermal aktivitede (SRR/SRL) önemli bir asimetri bulunmamış, fakat SRR latansının önemli farklılık taşıdığı gözlenmiştir. İşitsel uyaran için, ipsilateral yanıtların kontralateral yanıtlardan daha hızlı olması, limbik sistemin uyarıldığı durumda gözlenen bilateral EDA'nın ipsilateral kontrol altında olduğunu düşündürmektedir. Motor aktivasyona karşı gözlenen yanıt latansı, kullanılan uyarı bölgesinden bağımsız olarak, dominant elde daha küçüktür. Bu sonuç, tercihli olarak sağ elini kullanan bireylerde, sol bazal gangliyonun sağdakinden daha aktif olduğunu düşündürmektedir. Sonuçlar, korteks ve periferik yapıların her ikisinin de EDA üzerindeki etkilerinin önemini vurgularken, bu durum yanıtın latansında görülen asimetriyi modüle eden bir tek kortikal mekanizmanın bulunmadığını göstermektedir.

Anahtar Kelimeler: Bilateral EDA, Latans, Hemisferik asimetri
ABSTRACT
Research in cerebral laterality supports the idea of functional differences between the left and right hemispheres and suggest that a component of autonomic nervous system, electrodermal activity (EDA), is also lateralized. To evaluate the bilateral asymmetries in palmar EDA and the usefulness of EDA parameters as indices of relative hemispheric activation, skin resistance level (SRL), skin resistance response (SRR) and the SRR latency (L) were examined in 25 right-handed male subjects. We used bilateral recording with a unilateral stimulation (auditory click/patellar tendon tap) to assess the asymmetries of EDA variables related to the side of stimulation and to handedness. No significant asymmetry in EDA (SRR/SRL) were found but significant differences in latency were observed. Ipsilateral responses were faster than contralateral responses for auditory stimulus and this result suggest that the human bilateral EDA is under ipsilateral control when limbic structures are stimulated. Response latency to motor activation were smaller in dominant hand, regardless of the stimulation site used. This result indicates that the left basal ganglia were more active than the right for right handers. Results underline the importance both of the cortical and peripheral influences on EDA but argue against the existence of single cortical mechanism modulating the asymmetries in the latency of this response.

Keywords: Bilateral EDA, Latency, Hemispheric asymmetry.

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