Turkiye Klinikleri Journal of Medical Sciences

.: REVIEW
Fetal Yara İyileşmesi: Literatürün Gözden Geçirilmesi
FETAL WOUND HEALING: A REVIEW OF THE LITERATURE
Ferruh BİNGÜLa, Doğan TUNCALIa, Serdar GÖKREMa, Gürcan ASLANa
aII. Plastik, Rekonstrüktif ve Estetik Cerrahi Kliniği, Ankara Eğitim ve Araştırma Hastanesi, ANKARA
Turkiye Klinikleri J Med Sci. 2005;25(4):569-75
Article Language: TR
Full Text
ÖZET
Bu çalışmada; fetal yara iyileşmesinde rol oynayan faktörler ve erişkin yara iyileşmesi ile olan farklılıklar literatür ışığı altında tartışılmıştır. İntrauterin skarsız iyileşme, plastik cerrahi kliniklerinde sıkça karşılaşılan yarık dudak ve yarık damak gibi fasiyal dismorfolojilerdeki skar oluşumunu oldukça azaltabilir ya da engelleyebilir. Bununla birlikte riskleri nedeniyle açık fetal cerrahinin günümüzde sadece yaşamı tehdit eden anomaliler için uygulanması tavsiye edilmektedir. Kraniyofasiyal anomaliler için fetal cerrahi; açık fetal cerrahinin tabiatında olan riskleri hem anne hem de fetüs için doğurabilir. Fakat bazı çalışmacılar yeni endoskopik cerrahi yaklaşımlarla, seçilmiş hasta gruplarında, fetal cerrahinin güvenle uygulanabileceğini savunurlar. Plastik cerrahide ana hedef, fonksiyon ve yapıların restorasyonu yanında en az skar oluşturmaktır. Gelecekte yapılacak çalışmalarla fetal yara iyileşmesinin tüm sırlarını çözmek, ideal doku onarımı için güzel bir model oluşturabilecektir.

Anahtar Kelimeler: Skar, fetal yara iyileşmesi, plastik cerrahi,açık fetal cerrahi
ABSTRACT
In this study, we discuss the factors that play a role in fetal wound healing and differentiate these with those at work in adult wound healing. According to the current literature, in utero scar-less wound healing may minimize or even prevent the facial dysmorphology associated with anomalies frequently encountered in plastic surgery clinics, such as cleft lip and palate. However, human fetal surgery has to date been recommended only for a minority of patients with life-threatening fetal conditions. Fetal surgery for craniofacial anomalies does not justify the inherent risks of surgery to both mother and fetus. Nevertheless, some researchers claim that in selected patients, should the maternal-fetal safety risks be considered to be at acceptably low levels and endoscopic surgery is indicated, fetal surgery can be safely performed. The restoration of structure and function is the primary goal in plastic surgery. With the help of further research that will hopefully reveal the mechanisms of fetal wound healing, a blueprint for ideal tissue repair may be attained in the future.

Keywords: Cicatrix, fetal wound healing, surgery,plastic surgery

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30.03.2014

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