Turkiye Klinikleri Journal of Dental Sciences

.: ORIGINAL RESEARCH
Farklı İçeriklere Sahip Ağız Gargaralarının Gömülü Üçüncü Molar Cerrahileri Sonrası Gözlenen İnflamatuar Komplikasyonlar ve Erken Yara İyileşmesi Üzerine Etkilerinin Karşılaştırılması: Randomize Klinik Çalışma
Comparison of the Effects of the Mouthwashes with Different Ingredients on Inflammatory Complications and Early Wound Healing After Impacted Third Molar Surgery: Randomized Clinical Trial
Mustafa Sami DEMİRSOYa, Aras ERDİLb,c, Mehmet Kemal TÜMERd
aSakarya Üniversitesi Diş Hekimliği Fakültesi, Ağız, Diş ve Çene Cerrahisi ABD, Sakarya, TÜRKİYE
bSivas Ağız ve Diş Sağlığı Hastanesi, Ağız, Diş ve Çene Cerrahisi Kliniği, Sivas, TÜRKİYE
cUşak Üniversitesi Diş Hekimliği Fakültesi, Ağız, Diş ve Çene Cerrahisi ABD, Uşak, TÜRKİYE
dAlaaddin Keykubat Üniversitesi Diş Hekimliği Fakültesi, Ağız, Diş ve Çene Cerrahisi ABD, Antalya, TÜRKİYE
Turkiye Klinikleri J Dental Sci. 2022;28(1):21-30
doi: 10.5336/dentalsci.2021-83696
Article Language: TR
Full Text
ÖZET
 Amaç: Bu prospektif randomize klinik çalışmanın amacı, gömülü mandibular 3. molar dişlerin cerrahi çekimleri sonrası oluşan ağrı, ödem, trismus miktarları ve operasyon sahası iyileşmesi üzerine farklı içeriğe sahip gargara kullanımının etkilerini araştırmaktı. Gereç ve Yöntemler: Yaşları 18 ile 47 arasında değişen, Pederson zorluk indeksine göre orta zorlukta gömülü mandibular 3. molar dişlere sahip, 60 katılımcı çalışmaya dâhil edilmiştir. Katılımcılar randomize halde, her birinde 20 kişinin olduğu 3 gruba ayrılmıştır. Postoperatif olarak 1. gruba benzidamin HCl (%0,15)+klorheksidin glukonat (%0,12), 2. gruba çinko klorit (ZnCl2) (%0.02)+borik asit (H3BO3) (%0,01), 3. gruba propolis (%1)+klorheksidin glukonat (%0,02) içerikli gargaralar reçete edilmiştir. Maksimum ağız açıklığı, ödem, ağrı miktarları ve erken iyileşme indeksi skorları ameliyat öncesi ve sonrası 2 ve 7. günlerde ölçülmüştür. Bulgular: Postoperatif 2 ve 7. günde 1, 2 ve 3. grupların ağrı değerleri arasında (p=0,000 ve p=0,022) ve erken iyileşme skorları arasında (p=0,018, p=0,002) istatistiksel olarak anlamlı farklılıklar gözlenmiştir. Ayrıca postoperatif 2 ve 7. günde 1, 2 ve 3. grupların ağız açıklığı değerleri açısından, istatistiksel olarak 2. günde anlam bulunurken (p=0,020), 7. günde anlamlı bir fark görülmemiştir (p=0,425). Çalışma gruplarının ödem ölçümleri arasında ise takip sürecinde anlamlı farklılık tespit edilmemiştir. Sonuç: Gömülü mandibular 3. molar cerrahileri sonrası ortaya çıkan inflamatuar komplikasyonlar ve yara iyileşmesi açısından etkinliği araştırılan farklı içeriklere sahip ağız gargaralarının postoperatif rutin kullanımlarında olumlu etkiler oluşturabilecekleri gözlenmiştir.

Anahtar Kelimeler: Dişler, gömülü; yara iyileşmesi; postoperatif komplikasyonlar; propolis; borik asitler
ABSTRACT
 Objective: This prospective, randomized clinical trial aimed to investigate the effects of mouthwashes with different ingredients on pain, edema, trismus, and postoperative mucosal healing following surgical removal of impacted mandibular third molars. Material and Methods: Sixty participants, aged between 18-47, with impacted mandibular third molars, which had moderate surgical difficulty according to the Pederson difficulty index, were included. Participants were randomly divided into 3 groups, each containing 20 patients. In the first group Benzydamine HCl (0.15%)+ Chlorhexidine Gluconate (0.12%), in the second group Zinc Chloride (ZnCl2) (0.02%)+Boric Acid (H3BO3) (0.01%), and in the third group Propolis (1%)+Chlorhexidine Gluconate (0.02%) containing mouthwashes were prescribed. Maximum mouth opening, edema, pain measurements, and early healing index scores were examined pre- and postoperatively on the second and seventh days. Results: Significant differences were observed between the 1st, 2nd, and 3rd groups' pain (p=0.000 and p=0.022) and early healing index scores (p=0.018, p=0.002) in the postoperative second and seventh days. Also, maximum mouth opening measurements of the 1st, 2nd, and 3rd groups significantly differed on the postoperative second day (p=0.020), but the differences were insignificant on the postoperative seventh day (p=0.425). In edema measurements, no significant difference was observed between the groups, neither on the postoperative second day nor on the seventh day. Conclusion: It has been observed that postoperative routine use of mouthwashes with different ingredients, which have been evaluated regarding inflammatory complications and wound healing activities that occur following surgical removal of mandibular third molars, can reveal positive effects.

Keywords: Teeth, impacted; wound healing; postoperative complications; propolis; boric acids
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