From past to present, epilepsy, a long-term neurological condition marked by recurrent unprovoked seizures, has been linked to limitations in physical activity. Despite the proven benefits of exercise or physical activity in children with epilepsy, unfounded beliefs and misinformation, such as the idea that physical activity can trigger seizures or is dangerous for children with epilepsy, can influence attitudes of families and children about it, potentially leading to reduced participation in physical activities. The International League Against Epilepsy recommends physical activity for individuals diagnosed with epilepsy, highlighting that the benefits outweigh the risks. In 2016, the International League Against Epilepsy supported safe participation in sports for individuals with epilepsy, categorizing sports by their potential risk of injury or death during a seizure: minimal, moderate, or high risk. Swimming, water skiing, and sailing should be approached with caution and preferably conducted under supervision. For sports like bicycle racing, horseback riding, and gymnastics should be considered according to individual characteristics. Aerobic exercise is generally recommended for nearly all individuals with epilepsy. When recommending physical activity, it is important to consider the benefit/risk ratio, personal characteristics, seizure characteristics, and the nature of the physical activity. Physical activity can potentially reduce seizure frequency, improve mood and cognitive function, enhance overall physical health, and mitigate comorbidities which might result from epilepsy or its treatment, such as obesity and decreased bone quality. Therefore, children and adolescents should be encouraged to participate in sports activities at school or in recreational settings, while taking into account the associated risk classifications.
Keywords: Epilepsy; aerobic exercise; seizure; physical activity
Geçmişten bu yana, tekrarlayan provoke edilmemiş nöbetlerle kendini gösteren uzun süreli nörolojik bir durum olan epilepsi, fiziksel aktivite sınırlamalarıyla ilişkilendirilmiştir. Epilepsili çocuklarda egzersiz veya fiziksel aktivitenin kanıtlanmış faydalarına rağmen fiziksel aktivitenin nöbetleri tetikleyebileceği veya epilepsili çocuklar için tehlikeli olduğu fikri gibi asılsız inançlar ve yanlış bilgiler, ailelerin ve çocukların bu konuya yaklaşımını etkileyerek fiziksel aktivitelere katılımın azalmasına neden olabilmektedir. Uluslararası Epilepsi ile Savaş Ligi, epilepsi teşhisi konmuş bireyler için fiziksel aktiviteyi tavsiye etmekte ve faydalarının risklerinden daha ağır bastığını vurgulamaktadır. Uluslararası Epilepsi ile Savaş Ligi, 2016 yılında epilepsili bireylerin spora güvenli bir şekilde katılımını desteklemiş ve sporları nöbet sırasında yaralanma veya ölüm riskine göre kategorize etmiştir: minimal, orta veya yüksek risk. Yüzme, su kayağı ve yelken gibi aktivitelere dikkatle yaklaşılmalı ve tercihen gözetim altında yapılmalıdır. Bisiklet yarışı, ata binme ve jimnastik gibi sporlar için bireysel özellikler dikkate alınmalıdır. Aerobik egzersiz genellikle epilepsisi olan neredeyse tüm bireyler için önerilmektedir. Fiziksel aktivite önerirken fayda/risk oranını, kişisel özellikleri, nöbet özelliklerini ve fiziksel aktivitenin doğasını göz önünde bulundurmak önemlidir. Fiziksel aktivite potansiyel olarak nöbet sıklığını azaltabilir, ruh hâlini ve bilişsel işlevi iyileştirebilir, genel fiziksel sağlığı geliştirebilir ve obezite ve azalmış kemik kalitesi gibi epilepsi ile ilişkili komorbiditeleri hafifletebilir. Bu nedenle, çocuklar ve ergenler, ilgili risk sınıflandırmaları dikkate alınarak, okulda veya eğlence ortamlarında spor faaliyetlerine katılmaya teşvik edilmelidir.
Anahtar Kelimeler: Epilepsi; aerobik egzersiz; nöbet; fiziksel aktivite
- Beghi E, Giussani G, Sander JW. The natural history and prognosis of epilepsy. Epileptic Disord. 2015;17(3):243-53. [Crossref] [PubMed]
- Häfele CA, Freitas MP, Gervini BL, de Carvalho RM, Rombaldi AJ. Who are the individuals diagnosed with epilepsy using the Public Health System in the city of Pelotas, southern Brazil? Epilepsy Behav. 2018;78:84-90. [Crossref] [PubMed]
- Zuberi SM, Wirrell E, Yozawitz E, Wilmshurst JM, Specchio N, Riney K, et al. ILAE classification and definition of epilepsy syndromes with onset in neonates and infants: position statement by the ILAE Task Force on Nosology and Definitions. Epilepsia. 2022;63(6):1349-97. [Crossref] [PubMed]
- Arida RM, Teixeira-Machado L. Physical exercise for children and adolescents with epilepsy: what have we learned? Seizure. 2023;111:1-8. [Crossref] [PubMed]
- Ahmad Shehata G. A review of epilepsy stigma in egypt. acta psychopathologica. OMICS Publishing Group. 2016;02(02):1-7. [Crossref]
- Yeni K, Tülek Z, Bebek N. Epilepsi Özyönetim Ölçeği geçerlik ve güvenirlik çalışması [Validity and reliability study of Epilepsy Self-Management Scale]. Epilepsi: Journal of the Turkish Epilepsi Society. 2020;26(1):12-9. [Crossref]
- Roth DL, Goode KT, Williams VL, Faught E. Physical exercise, stressful life experience, and depression in adults with epilepsy. Epilepsia. 1994;35(6):1248-55. [Crossref] [PubMed]
- Arida RM. Physical exercise and seizure activity. Biochim Biophys Acta Mol Basis Dis. 2021;1867(1):165979. [Crossref] [PubMed]
- Dustin IH, Resnick B, Galik E, Klinedinst NJ, Michael K, Wiggs E, et al. The feasibility and impact of the EMOVE intervention on self-efficacy and outcome expectations for exercise in epilepsy. J Neurosci Nurs. 2019;51(2):95-100. [Crossref] [PubMed] [PMC]
- McAuley JW, Long L, Heise J, Kirby T, Buckworth J, Pitt C, et al. A prospective evaluation of the effects of a 12-week outpatient exercise program on clinical and behavioral outcomes in patients with epilepsy. Epilepsy Behav. 2001;2(6):592-600. [Crossref] [PubMed]
- Zhang H, Yu L, Li H, Liu Y. Effect of low glycaemic diet and structured exercise on quality of life and psychosocial functions in children with epilepsy. J Int Med Res. 2020;48(4):300060519893855. [Crossref] [PubMed] [PMC]
- Elliott JO, Jacobson MP. Bone loss in epilepsy: barriers to prevention, diagnosis, and treatment. Epilepsy Behav. 2006;8(1):169-75. [Crossref] [PubMed]
- Vooturi S, Lakshmi ANR, Jayalakshmi S. Adherence to exercise in people with epilepsy. Eur J Physiother. 2023;25(3):162-7. [Crossref]
- Sharma AA, Mackensie Terry D, Popp JL, Szaflarski JP, Martin RC, Nenert R, et al. Neuromorphometric associations with mood, cognition, and self-reported exercise levels in epilepsy and healthy individuals. Epilepsy Behav Rep. 2023;25:100643. [Crossref] [PubMed] [PMC]
- Feter N, Alt R, Dias MG, Rombaldi AJ. How do different physical exercise parameters modulate brain-derived neurotrophic factor in healthy and non-healthy adults? A systematic review, meta-analysis and meta-regression. Sci Sports. 2019;34(5):293-304. [Crossref]
- Capovilla G, Kaufman KR, Perucca E, Moshé SL, Arida RM. Epilepsy, seizures, physical exercise, and sports: a report from the ILAE Task Force on Sports and Epilepsy. Epilepsia. 2016;57(1):6-12. [Crossref] [PubMed]
- Syeda A, Karim MR. The mean age of petit mal epilepsy. J Pediatr Neurosci. 2016;11(2):112-4. [Crossref] [PubMed] [PMC]
- Sheth RD. Adolescent issues in epilepsy. J Child Neurol. 2002;17 Suppl 2:2S23-2S27. [Crossref] [PubMed]
- Green R, Abe C, Denney DA, Zhang R, Doyle A, Gadelmola K, et al. Physical activity status and quality of life in patients with epilepsy - Survey from level four epilepsy monitoring units. Epilepsy Res. 2021;173:106639. [Crossref] [PubMed]
- Vancampfort D, Ward PB, Stubbs B. Physical activity and sedentary levels among people living with epilepsy: a systematic review and meta-analysis. Epilepsy Behav. 2019;99:106390. [Crossref] [PubMed]
- Ogwumike O, Agboke M, Adeniyi A. Association between physical activity level and health-related quality of life of children with and without epilepsy. Journal of Pediatric Neurology. 2016;14(03):095-101. [Crossref]
- Wong J, Wirrell E. Physical activity in children/teens with epilepsy compared with that in their siblings without epilepsy. Epilepsia. 2006;47(3):631-9. [Crossref] [PubMed]
- Sırtbaş G, Yalnızoğlu D, Livanelioğlu A. Comparison of physical fitness, activity, and quality of life of the children with epilepsy and their healthy peers. Epilepsy Res. 2021;178:106795. [Crossref] [PubMed]
- Pohl D, Alpous A, Hamer S, Longmuir PE. Higher screen time, lower muscular endurance, and decreased agility limit the physical literacy of children with epilepsy. Epilepsy Behav. 2019;90:260-5. [Crossref] [PubMed]
- Dimitri P, Joshi K, Jones N; Moving Medicine for Children Working Group. Moving more: physical activity and its positive effects on long term conditions in children and young people. Arch Dis Child. 2020;105(11):1035-40. [Crossref] [PubMed]
- Brna PM, Gordon KE, Woolridge E, Dooley JM, Wood E. Perceived need for restrictions on activity for children with epilepsy. Epilepsy Behav. 2017;73:236-9. [Crossref] [PubMed]
- Wilfred AM, Humphreys C, Patterson S, Brown DM, Pohl D, Moyes C, et al. Being physically active with epilepsy: Insights from young people and their parents. Epilepsy Res. 2022;188:107035. [Crossref] [PubMed]
- Arida RM, Scorza FA, Terra VC, Scorza CA, de Almeida AC, Cavalheiro EA. Physical exercise in epilepsy: what kind of stressor is it? Epilepsy Behav. 2009;16(3):381-7. [Crossref] [PubMed]
- Nakken KO. Physical exercise in outpatients with epilepsy. Epilepsia. 1999;40(5):643-51. [Crossref] [PubMed]
- Arida RM, Cavalheiro EA, da Silva AC, Scorza FA. Physical activity and epilepsy: proven and predicted benefits. Sports Med. 2008;38(7):607-15. [Crossref] [PubMed]
- Téllez-Zenteno JF, Hunter G, Wiebe S. Injuries in people with self-reported epilepsy: a population-based study. Epilepsia. 2008;49(6):954-61. [Crossref] [PubMed]
- Pimentel J, Tojal R, Morgado J. Epilepsy and physical exercise. Seizure. 2015;25:87-94. [Crossref] [PubMed]
- Arida RM, Scorza FA, Gomes da Silva S, Schachter SC, Cavalheiro EA. The potential role of physical exercise in the treatment of epilepsy. Epilepsy Behav. 2010;17(4):432-5. [Crossref] [PubMed]
- Ronen GM, Janssen I. Patterns of daily activity among young people with epilepsy. Dev Med Child Neurol. 2019;61(12):1386-91. [Crossref] [PubMed]
- Alexander HB, Arnel M, O'Connell N, Munger Clary HM, Fanning J, Brubaker P, et al. A single-center survey on physical activity barriers, behaviors and preferences in adults with epilepsy. Epilepsy Behav. 2023;149:109491. [Crossref] [PubMed] [PMC]
- Carrizosa-Moog J, Ladino LD, Benjumea-Cuartas V, Orozco-Hernández JP, Castrillón-Velilla DM, Rizvi S, et al. Epilepsy, physical activity and sports: a narrative review. Can J Neurol Sci. 2018;45(6):624-32. [Crossref] [PubMed]
- Lin XY, Cui Y, Wang L, Chen W. Chronic exercise buffers the cognitive dysfunction and decreases the susceptibility to seizures in PTZ-treated rats. Epilepsy Behav. 2019;98(Pt A):173-87. [Crossref] [PubMed]
- Collard SS, Ellis-Hill C. How do you exercise with epilepsy? Insights into the barriers and adaptations to successfully exercise with epilepsy. Epilepsy Behav. 2017;70(Pt A):66-71. [Crossref] [PubMed]
- Willis J, Hophing L, Mahlberg N, Ronen GM. Youth with epilepsy: their insight into participating in enhanced physical activity study. Epilepsy Behav. 2018;89:63-9. [Crossref] [PubMed]
- Sallis JF, Prochaska JJ, Taylor WC. A review of correlates of physical activity of children and adolescents. Med Sci Sports Exerc. 2000;32(5):963-75. [Crossref] [PubMed]
- Vancampfort D, Ward PB. Physical activity correlates across the lifespan in people with epilepsy: a systematic review. Disabil Rehabil. 2021;43(10):1359-66. [Crossref] [PubMed]
- Tedrus GMAS, Sterca GS, Pereira RB. Physical activity, stigma, and quality of life in patients with epilepsy. Epilepsy Behav. 2017;77:96-8. [Crossref] [PubMed]
- Johnson EC, Helen Cross J, Reilly C. Physical activity in people with epilepsy: a systematic review. Epilepsia. 2020;61(6):1062-81. [Crossref] [PubMed]
- Popp JL, Szaflarski JP, Kaur M, Martin RC, Brokamp GA, Terry DM, et al. Relationships between cognitive function, seizure control, and self-reported leisure-time exercise in epilepsy. Epilepsy Behav. 2021;118:107900. [Crossref] [PubMed]
- Alexander HB, Allendorfer JB. The relationship between physical activity and cognitive function in people with epilepsy: a systematic review. Epilepsy Behav. 2023;142:109170. [Crossref] [PubMed] [PMC]
- Duñabeitia I, Bidaurrazaga-Letona I, Diz JC, Colon-Leira S, García-Fresneda A, Ayán C. Effects of physical exercise in people with epilepsy: a systematic review and meta-analysis. Epilepsy Behav. 2022;137(Pt A):108959. [Crossref] [PubMed]
- Löscher W, Klein P. The pharmacology and clinical efficacy of antiseizure medications: from bromide salts to cenobamate and beyond. CNS Drugs. 2021;35(9):935-63. Erratum in: CNS Drugs. 2021;35(9):1033-4. [Crossref] [PubMed] [PMC]
- Kumar M, Ramanujam B, Barki S, Dwivedi R, Vibha D, Singh RK, et al. Impact of exercise as a complementary management strategy in people with epilepsy: a randomized controlled trial. Epilepsy Behav. 2022;129:108616. [Crossref] [PubMed]
- Häfele CA, Rombaldi AJ, Feter N, Häfele V, Gervini BL, Domingues MR, et al. Effects of an exercise program on health of people with epilepsy: a randomized clinical trial. Epilepsy Behav. 2021;117:107904. [Crossref] [PubMed]
- Burtscher J, Schwarzer C. The opioid system in temporal lobe epilepsy: functional role and therapeutic potential. Front Mol Neurosci. 2017;10:245. [Crossref] [PubMed] [PMC]
- Holmes PV, Reiss JI, Murray PS, Dishman RK, Spradley JM. Chronic exercise dampens hippocampal glutamate overflow induced by kainic acid in rats. Behav Brain Res. 2015;284:19-23. [Crossref] [PubMed]
- Witt JA, Helmstaedter C. Should cognition be screened in new-onset epilepsies? A study in 247 untreated patients. J Neurol. 2012;259(8):1727-31. [Crossref] [PubMed]
- Feter N, Alt R, Häfele CA, da Silva MC, Rombaldi AJ. Effect of combined physical training on cognitive function in people with epilepsy: Results from a randomized controlled trial. Epilepsia. 2020;61(8):1649-58. [Crossref] [PubMed]
- Eom S, Lee MK, Park JH, Jeon JY, Kang HC, Lee JS, et al. The impact of an exercise therapy on psychosocial health of children with benign epilepsy: a pilot study. Epilepsy Behav. 2014;37:151-6. [Crossref] [PubMed]
- Hinnell C, Williams J, Metcalfe A, Patten SB, Parker R, Wiebe S, et al. Health status and health-related behaviors in epilepsy compared to other chronic conditions--a national population-based study. Epilepsia. 2010;51(5):853-61. [Crossref] [PubMed]
- Corbitt RW, Cooper DL, Erickson DJ, Kriss FC, Thornton ML, Craig TT. Editorial: epileptics and contact sports. JAMA. 1974;229(7):820-1. [Crossref] [PubMed]
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