Turkiye Klinikleri Journal of Dermatology

.: ORIGINAL RESEARCH
Evaluation of Factors That May Affect Success of Cryotherapy in the Treatment of Warts: A Retrospective Cross-Sectional Study
Siğil Tedavisinde Kriyoterapinin Başarısını Etkileyebilecek Faktörlerin Değerlendirilmesi: Retrospektif Kesitsel Bir Çalışma
Nurşad ÇİFCİa, Hatice KAYA ÖZDENa
aClinic of Dermatology, Kocaeli Derince Training and Research Hospital, Kocaeli, Türkiye
Turkiye Klinikleri J Dermatol. 2022;32(1):9-15
doi: 10.5336/dermato.2021-86125
Article Language: EN
Full Text
ABSTRACT
 Objective: Success of the treatment of warts with cryotherapy differs from patient to patient. We aimed to evaluate how the age and gender of the patient, the type, number, duration, localization of warts and cryotherapy session intervals affect the success of treatment. Material and Methods: After ethics committee approval had been received, the medical files of patients with diagnosis of wart, between June 2016 and June 2019, were analysed retrospectively. Demographic and clinical features of patients were recorded. Patients who did not improve clinically after 6 sessions were considered resistant to treatment. Demographic and clinical features were compared between treatment resistant and non-resitant groups by using SPSS 17 (Chicago, IL, USA), twosided p value 10 mm were compared and resistance rates were found respectively 14.7%, 31.5%, 60%. Difference between subgroups was statistically significant (p=0.01). The mean age, lesion localization, lesion number, verruca subtype, duration of the disease and the session intervals for both groups were found similar (p>0.05). Conclusion: Treatment success was found to be lower in women and in patients with larger warts.

Keywords: Warts; cryotherapy; treatment failure; female
ÖZET
 Amaç: Kriyoterapi ile siğil tedavisinin başarısı hastadan hastaya farklılık göstermektedir. Hastanın yaşı ve cinsiyeti, siğillerin tipi, sayısı, süresi, lokalizasyonu ve kriyoterapi seans aralıklarının tedavi başarısını nasıl etkilediğini değerlendirmeyi amaçladık. Gereç ve Yöntemler: Etik kurul onayı alındıktan sonra Haziran 2016 ile Haziran 2019 tarihleri arasında siğil tanısı alan hastaların tıbbi dosyaları retrospektif olarak incelendi. Hastaların demografik ve klinik özellikleri kaydedildi. 6 seans sonrasında klinik olarak düzelmeyen hastalar tedaviye dirençli olarak kabul edildi. Tedaviye dirençli ve dirençli olmayan gruplar arasında demografik ve klinik özellikler SPSS 17 (Chicago, IL, USA) kullanılarak karşılaştırıldı, iki taraflı p değeri <0,05 istatistiksel olarak anlamlı kabul edildi. Bulgular: 98 hastanın 56'sı (%57.2) kadın, 42'si (%42.8) erkekti. Ortalama yaş 21.98±12.80 yıl idi. Tüm hastalardan 28'i (%28.6) tedaviye dirençli idi. Dirençli grupta K/E oranı 20/8 (%71,4/28,6), dirençli olmayan grupta 36/34 (%51,4/48,6) idi. Gruplar arasındaki fark istatistiksel olarak anlamlıydı (p=0.04). Siğil boyutları 0-4,9 mm, 5-10 mm, >10 mm olan hastalar karşılaştırılmış ve direnç oranları sırasıyla %14.7, %31.5, %60 olarak bulundu. Alt gruplar arasındaki fark istatistiksel olarak anlamlıydı (p=0.01). Her iki grubun yaş ortalaması, lezyon lokalizasyonu, lezyon sayısı, verruka alt tipi, hastalık süresi ve seans aralıkları benzer bulundu (p>0.05). Sonuç: Kadınlarda ve daha büyük siğilleri olan hastalarda tedavi başarısı daha düşük bulundu.

Anahtar Kelimeler: Siğiller; kriyoterapi; tedavi başarısızlığı; kadın
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