Turkiye Klinikleri Journal of Dermatology

.: ORIGINAL RESEARCH
Do Patients with Psoriasis Suffer from Hearing Loss?
Psöriyazis Hastalarında İşitme Kaybı Olur mu?
Gülhan GÜRELa, Yunus KANTEKİNb, İlknur HABERAL CANb
Departments of
aDermatology,
bOtorhinolaringology, Yozgat Bozok University Faculty of Medicine, Yozgat, TURKEY
Turkiye Klinikleri J Dermatol. 2019;29(3):101-7
doi: 10.5336/dermato.2019-70659
Article Language: EN
Full Text
ABSTRACT
 Objective: Sensorineural hearing loss has been associated with various diseases including vitiligo, rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease and Behcet's disease in the etiopathogenesis of which autoimmunity and chronic inflammation play a role. However, limited studies are available evaluating hearing levels in psoriasis which is another chronic inflammatory and autoimmune disease. The present study evaluates hearing levels in patients with psoriasis, a chronic inflammatory disease which are often accompanied by other comorbid conditions, and makes a comparison with healthy controls. Material and Methods: Fifty psoriasis patients and 50 healthy volunteers were included in the study. All participating patients underwent a complete otorhinolaryngologic examination prior to undergoing audiometry. The patients underwent pure-tone audiometry in an audiometry laboratory with voice isolation. Results: In the present study, statistically significant differences were noted between the groups in terms of hearing threshold in both left and right ear at 2000 Hz, and in the right ear at 4000 Hz and 8000 Hz. In all instances of significant difference, the patients in the psoriasis group had higher values. The mean air- and bone-conduction hearing thresholds in the left and right ear were significantly higher in the psoriasis group (p<0.05). The correlation analysis which was made to identify any possible relationship between Psoriasis Area Severity Index (PASI) and duration of disease revealed no significant relationship or correlation. Conclusion: It should be kept in mind that hearing loss can occur in psoriasis patients, and they should be followed up regularly with audiometry.

Keywords: Audiometry; hearing loss; psoriasis
ÖZET
 Amaç: Sensörinöral işitme kaybı vitiligo, romatoid artrit, sistemik lupus eritematozus, inflamatuvar barsak hastalığı ve Behçet hastalığı gibi etyopatogenezinde otoimmünitenin ve kronik inflamasyonun rol oynadığı birçok hastalık ile ilişkilidir. Fakat psoriasis gibi kronik inflamatuar ve otoimmün bir hastalıkta işitme düzeyini değerlendiren kısıtlı sayıda çalışma vardır. Bu çalışma, pek çok komorbiditeler ile birlikte olabilen, kronik inflamatuar bir hastalık olan psoriasiste işitme düzeyini sağlıklı kontrol grubu ile karşılaştırmalı olarak değerlendirmektedir. Gereç ve Yöntemler: Çalışmaya 50 psöriyazis hastası ile 50 sağlıklı gönüllü dahil edildi. Çalışmaya katılan tüm hastalara işitme testi yapılmadan önce tam bir kulak, burun, boğaz muayenesi yapıldı. Ardından hastalara ses izolasyonu sağlanmış odyometri laboratuvarında saf ses odyometri değerlendirmesi yapıldı. Bulgular: Bu çalışmada 2000 Hz'de hem sol kulak hem de sağ kulak işitme eşiği değerleri yönünden, 4000 ve 8000 Hz'de sağ kulak işitme eşiği değerleri yönünden gruplar arasında istatistiksel olarak anlamlı bir fark olduğu bulunmuştur. Fark bulunan tüm durumlarda psöriyazis grubunun değerlerinin daha yüksek olduğu görülmüştür. Hava yolu ve kemik yolunda hem sol kulak hem de sağ kulak ortalama işitme değerleri yönünden psöriyazis grubunun değerlerinin istatistiksel olarak anlamlı şekilde yüksek olduğu saptanmıştır (p<0.05). Psöriyazis Alan Şiddet İndeksi (PASI) skoru ve hastalık süresiyle işitme kaybı arasında korelasyon analizinde anlamlı bir ilişki ve korelasyon olmadığı görülmüştür. Sonuç: Psöriyazis hastalarında işitme kaybı olabileceği akılda tutulmalı ve odyometri ile düzenli olarak izlenmelidir.

Anahtar Kelimeler: Odyometri; işitme kaybı; psöriyazis
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