Turkiye Klinikleri Journal of Dermatology

.: ORIGINAL RESEARCH
Cutaneous Findings of COVID-19 Infection Related with Length of Hospital Stay: A Prospective, Multicenter Study
COVID-19 Enfeksiyonunun Hastanede Yatış Süresiyle İlişkili Kutanöz Bulguları: Prospektif, Çok Merkezli Çalışma
Aslı TATLIPARMAKa, Zehra AŞİRAN SERDARb, Selda Pelin KARTALc , Gökçen ÇELİKd, Fatmanur HACINECİPOĞLUe, Şirin YURTLU TEMELf, Gizem KOCABAŞ YENİPAZARg, İnci SERDARh, Ali Cankut TATLIPARMAKı
aDepartment of Dermatology, İstinye University Faculty of Medicine, İstanbul, Türkiye
bDepartment of Dermatology, İstanbul Yeni Yüzyıl University Faculty of Medicine, İstanbul, Türkiye
cDepartment of Dermatology, University of Health Sciences Dışkapı Training and Research Hospital, Ankara, Türkiye
dClinic of Dermatology, Yozgat State Hospital, Yozgat, Türkiye
eClinic of Dermatology, Ankara Gazi Mustafa Kemal State Hospital, Ankara, Türkiye
fDepartment of Pulmonary Diseases, İstinye University Faculty of Medicine, İstanbul, Türkiye
gClinic of Dermatology, Denizli State Hospital, Denizli, Türkiye
hHumanitas University School of Medicine, Milan, Italy
ıClinic of Emergency Medicine, Arnavutköy State Hospital, İstanbul, Türkiye
Turkiye Klinikleri J Dermatol. 2022;32(1):56-61
doi: 10.5336/dermato.2021-86767
Article Language: EN
Full Text
ABSTRACT
 Objective: Coronavirus disease-2019 (COVID-19) was declared a pandemic in March 2020. As the number of cases increased, the infection emerged as a multi-systemic disease. Respiratory, cardiac, hepatic, urinary, circulatory, gastrointestinal systems and finally skin may be the target organs of COVID-19. The aim of this study was to evaluate the cutaneous signs of COVID-19 and their effect on the patients' prognosis. Material and Methods: A total of 192 hospitalized COVID-19 cases, between May 2021 to July 2021 were included in the study. The length of stay (LoS) of the patients were recorded. Hospitalization and discharge decisions and all treatments of the patients were determined at the discretion of the treating physician according to the pandemic guidelines of the Ministry of Health. Fever, fatigue, cough, dyspnea, myalgia, anosmia, and headache were considered COVID-19 symptoms. Results: Dermatological manifestations were seen in 10 cases. LoS in the group with dermatological findings was shorter than the group without dermatological findings and the difference was statistically significant between the groups. Discharge of the patients was the endpoint of the study. Conclusion: Our multicenter study suggests that patients with cutaneous findings usually do not have classical symptoms for COVID-19 and have a shorter LoS.

Keywords: COVID-19; dermatology; length of stay; pandemics; prognosis
ÖZET
 Amaç: Koronavirüs hastalığı-2019 [coronavirus disease-2019 (COVID-19)], Mart 2020 tarihinde pandemi ilan edildi. Vaka sayısı arttıkça enfeksiyon multisistemik bir hastalık olarak gözlemlenmeye başlandı. Solunum, kardiyak, hepatit, renal, vasküler, gastrointestinal sistemler ve son olarak deri, COVID-19'un hedef organları olabilmektedir. Bu çalışmanın amacı, COVID-19'un kutanöz belirtilerini ve bunların hasta prognozu üzerindeki etkisini değerlendirmektir. Gereç ve Yöntemler: Mayıs-Temmuz 2021 tarihleri arasında hastanede yatan toplam 192 COVID-19 vakası çalışmaya dâhil edildi. Hastaların, hastanede kalış süreleri [length of stay (LoS)] kaydedildi. Hastaların yatış ve taburculuk kararları ve tüm tedavileri, Sağlık Bakanlığının pandemi kılavuzlarına göre tedaviyi yapan hekimin inisiyatifinde belirlendi. Ateş, yorgunluk, öksürük, nefes darlığı, miyalji, anosmi ve baş ağrısı, COVID-19 semptomları olarak kabul edildi. Bulgular: On olguda dermatolojik bulgular görüldü. Dermatolojik bulgusu olan gruptaki LoS, dermatolojik bulgusu olmayan gruba göre daha kısaydı ve gruplar arasındaki fark istatistiksel olarak anlamlıydı. Hastaların taburcu edilmesi çalışmanın bitiş noktasıydı. Sonuç: Çok merkezli çalışmamız, kutanöz bulguları olan hastaların genellikle COVID-19 için klasik semptomlarının olmadığını ve daha kısa bir LoS'a sahip olduğunu göstermektedir.

Anahtar Kelimeler: COVID-19; dermatoloji; yatış süresi; pandemik; prognoz
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