Turkiye Klinikleri Journal of Veterinary Sciences

.: ORIGINAL RESEARCH
Colon Wall Thickness at the Cross Roads of GastroenteroDermatology Among Diseased Dogs: Clinical Research
Hasta Köpeklerde Gastroentero-Dermatoloji Kavşağında Kolon Duvar Kalınlığı: Klinik Araştırma
Kerem URALa, Hasan ERDOĞANa, Songül ERDOĞANa, Gamze GÖKÇAYa, Cansu BALIKÇIa
aDepartment of Internal Medicine, Aydın Adnan Menderes University Faculty of Veterinary Medicine, Aydın, Türkiye
Turkiye Klinikleri J Vet Sci. 2023;14(2):47-53
doi: 10.5336/vetsci.2022-94997
Article Language: EN
Full Text
ABSTRACT
 Objective: Utilization for bowel ultrasonography (USG) in humans has been thoroughly recognized, whereas less bull's eye has been concentrated on specifical USG analytes on colon during disease state among dogs. Lack of literature and the evidence of proof for ''gut-brain-skin axis'' prompted us to focus on patterns of colon wall architectural alterations during disease activity among dogs with gastroentero-dermatological involvement. Out of the classical pictorial essay interpretations composed of normal bowel wall architecture detailed elsewhere, the present study prospectively involved dogs with inflammatory bowel disease (IBD) and comorbidity (with evidence of dermatological disorder). Material and Methods: The colon wall thickness (coWt) of 8 dogs with gastroentero-dermatological disease, as measured by ultrasonography, was compared with apparently healthy dogs with proposed normal values. Complete dermatological and gastroenterological laboratory analysis (relevant and necessary ones) were deemed available. Results: In dogs with IBD increased coWt were evident in contrast to healthy ones, reflected as 3.661.28 vs. 2.070.44 (p=0.012). Although ultrasonographic intestinal wall measurements do not appear to be capable of establishing a diagnosis of intestinal inflammation, it should not be unwise to draw preliminary conclusion that coWt might alter in gastroentero-dermatological diseases. Conclusion: The same ''grey zone'' of between 1 and 2.6 mm adapted in healthy dogs could be used in the canine colon to distinguish the reference range, reserving the term ''abnormal'' for a coWt of greater than 3.1 mm in the colon, at least for dogs with IBD.

Keywords: Canine intestine; gastro-dermal axis; inflammatory bowel disease; ultrasonography
ÖZET
 Amaç: Bağırsak ultrasonografisi (USG), insanlarda tüm kompartmanlarda bakılırken, hasta köpeklerde kolonun spesifik USG analizleri daha az hedef alınarak yoğunlaşılır. ''Bağırsak-beyin-deri ekseni'' üzerine literatür ve teşhisi için bulguların eksikliği, aktif gastroentero-dermatolojik tutulumu olan hasta köpeklerde kolon duvarının yapısal değişim paternlerine odaklanmamızı sağlar. Daha ayrıntılı bir şekilde, normal bağırsak duvarı yapısından oluşan klasik girişimsel görüntüleme yorumları, bu çalışmada prospektif olarak inflamatuar bağırsak hastalığı (İBD) ve komorbidite hastalığı (dermatolojik hastalık bulgulu) olan köpeklerden yapılacaktır. Gereç ve Yöntemler: Kolon duvar kalınlığı [colon wall thickness (coWt)], ultrasonografik ölçüm yapılarak gastroentero-dermatolojik hastalıklı 8 köpeğin ölçümleri, önerilen normal değer aralığında sağlıklı görünüşe sahip köpeklerle karşılaştırıldı. Tamamlanan dermatolojik ve gastroenterolojik laboratuvar analizleri (ilgili ve gerekli olanlar) yeterli kabul edildi. Bulgular: Köpeklerde İBD bulunanlarda 3,661,28 ile sağlıklı olanların 2,070,44 aksine coWt değerlerinde artış belirgindi (p=0,012). Ultrasonografik bağırsak duvarı ölçümü, bağırsak inflamasyonunun teşhisi için yeterli gibi görünmese de coWt'nin değişiminin gastroentero-dermatolojik hastalıklarda güç bulunduğu ön tanısını çıkarmak amaca uygun değildir. Sonuç: Sağlıklı köpeklerde kullanılan 1-2,6 mm aralığındaki ''gri zon'' köpeklerde kolonun referans aralığının ayrımında kullanılabilmekle birlikte, en azından İBD bulunan köpeklerde coWt 3,1 mm'den daha büyük olması ''anormal'' olarak değerlendirilebilir.

Anahtar Kelimeler: Köpek bağırsak; gastro-dermal eksen; inflamatuar bağırsak hastalığı; ultrasonografi
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