Coffee is one of the world's most popular drinks. It is only an inspirational morning refreshment for some, but for others it has become a lifestyle beverage with a global consumption of billions cups per day. Because of its popularity, coffee has often been proposed to be able to prevent health problems and has attracted a great deal of research over the years. Although there has been limited research evaluating the effectiveness of coffee in ameliorating certain health conditions, there is a compelling evidence that coffee consumption has potential benefits for a variety of chronic diseases. Recent studies have confirmed that moderate amount of coffee consumption might have a role in protection against type 2 diabetes, metabolic syndrome, Parkinson's disease, Alzheimer's disease, depression, cognitive impairment, chronic liver disease, chronic kidney disease, prostate cancer, endometrial cancer, liver cancer, leukemia and cardiovascular diseases, including hypertension, coronary heart disease and venous thromboembolism. In dermatological point of view, currently there is a growing body of evidence suggesting that caffeine and other nutrients contained in coffee may protect against melanoma and non-melanoma skin cancer. Moreover, as the new data on coffee and health continues to get emerged, it is getting clear that coffee is also effective in inflammatory disease prevention, including inflammatory skin diseases. In this review, we focused on recent evidence about coffee and dermatological diseases and aimed to explore the link between coffee and melanoma/ non-melanoma skin cancers, psoriasis and rosacea.
Keywords: Coffee; melanoma; non-melanoma skin cancer; psoriasis; rosacea
Kahve dünyada en fazla tüketilen içecekler arasında yer alır. Kahve bazıları için sadece bir sabah uyaranı olabilir, ancak bazıları içinse günlük global tüketimi milyarlarla ölçülen bir hayat tarzı içeceğidir. Popularitesi nedeniyle, kahvenin sıklıkla sağlık problemlerini önlediği ileri sürülmüş ve kahve yıllar içerisinde çok sayıda araştırmanın başlıca konularından biri olmuştur. Her ne kadar, kahvenin bazı hastalıkları iyileştirmesindeki etkinliği ile ilgili ortaya konmuş yeterli veri yoksa da, günümüzde kahvenin çok sayıda kronik hastalığın önlenmesinde faydalı olduğunu gösteren kayda değer veriler bulunmaktadır. Son yıllarda yapılan çalışmalar, makul düzeyde kahve tüketiminin tip 2 diyabet, metabolik sendrom, Parkinson hastalığı, Alzheimer hastalığı, depresyon, kognitif bozukluklar, kronik karaciğer hastalığı, kronik böbrek hastalığı, prostat kanseri, endometrium kanseri, karaciğer kanseri, lösemi ve hipertansiyon, koroner arter hastalığı ve venöz tromboembolizmi de içeren kardiyovasküler hastalıklara karşı koruyucu rol oynayabileceğini göstermiştir. Dermatolojik açıdansa, kahvede bulunan kafein ve diğer bileşenlerin melanoma ve melanom dışı deri kanserlerine karşı koruyucu olduğunu gösteren veriler gün geçtikçe artmaktadır. Dahası, kahve ve sağlıkla ilgili yeni veriler ortaya çıktıkça, kahvenin inflamatuar deri hastalıkları da dahil olmak üzere, inflamatuar hastalıkların önlenmesinde etkili olduğu daha anlaşılır düzeye ulaşmış bulunmaktadır. Bu derlemede, kahve ve deri hastalıkları ile ilgili güncel literatüre odaklandık ve kahve ile melanom, melanom dışı deri kanseri, psöriazis ve rozaseanın ilişkisini irdelemeyi hedefledik.
Anahtar Kelimeler: Kahve; melanom; melanom dışı deri kanseri; psöriazis; rozasea
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