Amaç: Çocuklarda üst üriner sistem taşlarında, taş boyutunun retrograd intrarenal cerrahi sonuçları üzerine etkisinin araştırılması. Gereç ve Yöntemler: 2015-2021 yılları arasında ameliyat edilmiş 29 hastaya ait 38 renal ünite araştırıldı. Demografik veriler, taşın yerleşim yeri, operasyon süresi, access kılıf kullanımı, stent varlığı, komplikasyonlar, hastanede kalış süresi ve taşsızlık oranları retrospektif olarak incelendi. Hastalar, taş boyutu 2 cm'den küçük olanlar 1. grup, 2 cm ve daha büyük olanlar ise 2. grup olacak şekilde gruplara ayrıldı. İstatistiksel analiz için Mann-Whitney U testi; Ki-kare testi ve Fisher'ın kesin ki-kare testleri kullanıldı. Bulgular: Birinci gruptaki renal ünitelerin ait olduğu hastaların ortalama yaşı 11,26 (3-17) yıl, 2. grubun ise 15,2 (11-17) yıl idi ve aradaki yaş farkı istatistiksel olarak anlamlıydı (p=0.002). Gruplar arasında cinsiyet dağılımı açısından istatistiksel olarak anlamlı bir fark saptanmadı (p=0.254). Taş boyutları 1. grup için ortalama 13 (10-18) mm, 2. grup için ise ortalama 25,9 (20- 45) mm olarak hesaplandı. Birinci grupta ortalama operasyon süresi 51 (30-75) dk iken; 2. grupta ortalama operasyon süresi 66,7 (35-100) dk idi ve aradaki fark istatistiksel olarak anlamlıydı (p=0.014). Birinci gruptaki bir hastada postoperatif ilk 48 saat içerisinde ateş görülürken, 2. gruptaki hiçbir hastada postoperatif dönemde ateş olmadı. Birinci grupta tek seansta taşsızlık oranı %78,3, 2. grupta tek seansta taşsızlık oranı %60 olarak hesaplandı ve bu oranın istatistiksel olarak anlamlı olmadığı görüldü (p=0.285). Sonuç: Retrograd intrarenal cerrahi çocuklarda, özellikle 2 cm'den küçük üst üriner sistem taşlarında, kabul edilebilir taşsızlık oranı ile güvenli şekilde kullanılabilir.
Anahtar Kelimeler: Retrograd intrarenal cerrahi; üriner sistem taşı
Objective: To investigate the effect of stone size on retrograde intrarenal surgery results in upper urinary tract stones in children. Material and Methods: 38 renal units of 29 patients who were operated between 2015-2021 were investigated. Demographic data, stone location, operation time, acces sheath use, presence of JJ stent, complications, length of hospital stay and stone free rates were retrospectively analyzed. Patients who had stones smaller than 2 cm. were grouped as group 1 and, who had 2 cm. and larger were grouped as Group 2. Mann-Whitney U test, chi-square test and Fisher's exact chi-square tests were used for statistical analysis. Results: The mean age of the patients in group 1 to which the renal units belonged was 11.26 (3-17) years, and in Group 2 was 15.2 (11-17) years, and the age difference was statistically significant (p=0.002). There was no statistically significant difference between the groups in terms of gender distribution (p=0.254). Average stone size was 13 (10-18) mm for group 1, 25.9 (20-45) mm for group 2. In group 1, the mean operation time was 51 (30-75) minute and 66.7 (35-100) minutes in Group 2 and the difference was statistically significant (p=0.014). The stonefree rate after the first session was 78.3% in group 1, and 60% in group 2 and this difference was not statistically significant (p=0.285). Conclusion: Retrograde intrarenal surgery can be used safely with an acceptable stone-free rate, especially in children with upper urinary tract stones smaller than 2 cm.
Keywords: Retrograde intrarenal surgery; urinary system stone
- Sas DJ. An update on the changing epidemiology and metabolic risk factors in pediatric kidney stone disease. Clin J Am Soc Nephrol. 2011;6(8):2062-8. [Crossref] [PubMed]
- Önen A. Çocuklarda üriner sistem taş hastalığı [Urinary system stone disease in children]. Çocuk Cerrahisi Dergisi. 2013;27(1):8-32. [Link]
- Pietrow PK, Pope JC 4th, Adams MC, Shyr Y, Brock JW 3rd. Clinical outcome of pediatric stone disease. J Urol. 2002;167(2 Pt 1):670-3. [Crossref] [PubMed]
- Radmayr C, Bogaert G, Burgu B, et al. EAU Guidelines On Paeditric Urology. Edn. presented at the EAU Annual Congress Amsterdam 2022;3(15):81. ISBN 978-94-92671-16-5. [Link]
- Li J, Yu H, Zhou P, Pan H, Li R, Wang Y, et al. Application of flexible ureteroscopy combined with holmium laser lithotripsy and their therapeutic efficacy in the treatment of upper urinary stones in children and infants. Urol J. 2019;16(4):343-6. [PubMed]
- Tanaka ST, Makari JH, Pope JC 4th, Adams MC, Brock JW 3rd, Thomas JC. Pediatric ureteroscopic management of intrarenal calculi. J Urol. 2008;180(5):2150-3; discussion 2153-4. [Crossref] [PubMed]
- Dave S, Khoury AE, Braga L, Farhat WA. Single-institutional study on role of ureteroscopy and retrograde intrarenal surgery in treatment of pediatric renal calculi. Urology. 2008;72(5):1018-21. [Crossref] [PubMed]
- Huffman JL, Bagley DH, Lyon ES. Extending cystoscopic techniques into the ureter and renal pelvis. Experience with ureteroscopy and pyeloscopy. JAMA. 1983;250(15):2002-5. [Crossref] [PubMed]
- Wang W, Ge Y, Wang Z, Wang L, Li J, Tian Y. Comparing micropercutaneous nephrolithotomy and retrograde intrarenal surgery in treating 1-2 cm solitary renal stones in pediatric patients younger than 3 years. J Pediatr Urol. 2019;15(5):517.e1-517.e6. [Crossref] [PubMed]
- Ekici M, Ozgur BC, Senturk AB, Aydin C, Akdaglı Ekici A, Yaytokgil M, et al. Efficacy and reliability of retrograde intrarenal surgery in treatment of pediatric kidney stones. Cureus. 2018;10(12):e3719. [Crossref] [PubMed] [PMC]
- Sen H, Seckiner I, Bayrak O, Dogan K, Erturhan S. A comparison of micro-PERC and retrograde intrarenal surgery results in pediatric patients with renal stones. J Pediatr Urol. 2017;13(6):619.e1-619.e5. [Crossref] [PubMed]
- Unsal A, Resorlu B. Retrograde intrarenal surgery in infants and preschool-age children. J Pediatr Surg. 2011;46(11):2195-9. [Crossref] [PubMed]
- Saad KS, Youssif ME, Al Islam Nafis Hamdy S, Fahmy A, El Din Hanno AG, El-Nahas AR. Percutaneous Nephrolithotomy vs Retrograde Intrarenal Surgery for Large Renal Stones in Pediatric Patients: A Randomized Controlled Trial. J Urol. 2015;194(6):1716-20. [Crossref] [PubMed]
- Sofer M, Binyamini J, Ekstein PM, Bar-Yosef Y, Chen J, Matzkin H, et al. Holmium laser ureteroscopic treatment of various pathologic features in pediatrics. Urology. 2007;69(3):566-9. [Crossref] [PubMed]
- Smaldone MC, Cannon GM Jr, Wu HY, Bassett J, Polsky EG, Bellinger MF, et al. Is ureteroscopy first line treatment for pediatric stone disease? J Urol. 2007;178(5):2128-31; discussion 2131. [Crossref] [PubMed]
- Shokeir AA, Sheir KZ, El-Nahas AR, El-Assmy AM, Eassa W, El-Kappany HA. Treatment of renal stones in children: a comparison between percutaneous nephrolithotomy and shock wave lithotripsy. J Urol. 2006;176(2):706-10. [Crossref] [PubMed]
- Desai M. Endoscopic management of stones in children. Curr Opin Urol. 2005;15(2):107-12. [Crossref] [PubMed]
- Michel MS, Trojan L, Rassweiler JJ. Complications in percutaneous nephrolithotomy. Eur Urol. 2007;51(4):899-906; discussion 906. [Crossref] [PubMed]
- Resorlu B, Unsal A, Tepeler A, Atis G, Tokatli Z, Oztuna D, et al. Comparison of retrograde intrarenal surgery and mini-percutaneous nephrolithotomy in children with moderate-size kidney stones: results of multi-institutional analysis. Urology. 2012;80(3):519-23. [Crossref] [PubMed]
- Durkee CT, Balcom A. Surgical management of urolithiasis. Pediatr Clin North Am. 2006;53(3):465-77, vii. [Crossref] [PubMed]
- Defoor W, Dharamsi N, Smith P, Sekhon D, Colombo J, Riden D, et al. Use of mobile extracorporeal shock wave lithotripter: experience in a pediatric institution. Urology. 2005;65(4):778-81. [Crossref] [PubMed]
- Onal B, Demirkesen O, Tansu N, Kalkan M, Altintaş R, Yalçin V. The impact of caliceal pelvic anatomy on stone clearance after shock wave lithotripsy for pediatric lower pole stones. J Urol. 2004;172(3):1082-6. [Crossref] [PubMed]
- Aksoy Y, Ozbey I, Atmaca AF, Polat O. Extracorporeal shock wave lithotripsy in children: experience using a mpl-9000 lithotriptor. World J Urol. 2004;22(2):115-9. [Crossref] [PubMed]
- Muslumanoglu AY, Tefekli A, Sarilar O, Binbay M, Altunrende F, Ozkuvanci U. Extracorporeal shock wave lithotripsy as first line treatment alternative for urinary tract stones in children: a large scale retrospective analysis. J Urol. 2003;170(6 Pt 1):2405-8. [Crossref] [PubMed]
- Yuruk E, Tuken M, Gonultas S, Colakerol A, Cakir OO, Binbay M, et al. Retrograde intrarenal surgery in the management of pediatric cystine stones. J Pediatr Urol. 2017;13(5):487.e1-7.e5. [Crossref] [PubMed]
- Kim SS, Kolon TF, Canter D, White M, Casale P. Pediatric flexible ureteroscopic lithotripsy: the children's hospital of Philadelphia experience. J Urol. 2008;180(6):2616-9; discussion 2619. [Crossref] [PubMed]
- Kocakgol H, Aydin HR, Guctas AO, Sekerci CA, Ozturk Kocakgol D, Aksoy HZ, et al. Outcomes of fluoroscopy-free retrograde intrarenal surgery and predictive factors of stone-free. Arch Ital Urol Androl. 2021;93(4):425-30. [Crossref] [PubMed]
- Hubert KC, Palmer JS. Passive dilation by ureteral stenting before ureteroscopy: eliminating the need for active dilation. J Urol. 2005;174(3):1079-80; discussion 1080. [Crossref] [PubMed]
- Monga M, Gawlik A, Durfee W. Systematic evaluation of ureteral access sheaths. Urology. 2004;63(5):834-6. [Crossref] [PubMed]
- Traxer O, Thomas A. Prospective evaluation and classification of ureteral wall injuries resulting from insertion of a ureteral access sheath during retrograde intrarenal surgery. J Urol. 2013;189(2):580-4. [Crossref] [PubMed]
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