Objective: The aim of the study is to perform a bibliometric analysis to evaluate the biochemical studies in endodontics. Material and Methods: The electronic search was performed in the Web of Science database with no time limit until 10 October 2023. All articles related to biochemistry in endodontics were included. The modularity Q index, the average silhouette, and the centrality values were determined. Publication growth trends, citations, keywords, countries, journals, and authors were analyzed using CiteSpace and VOSviewer. Results: A total of 831 (754 original articles and 77 reviews) studies were analyzed. The average growth rate between 1978 and 2023 has been approximately 10.13%. The first study was published in 1978, and 71 countries performed studies, however, the USA, Brazil, Japan, and China were the lead ones. A total of 3998 authors contributed to the publications. The Journal of Endodontics was the lead for the number of studies. Conclusion: The increasing publication trend indicates an increasing interest in biochemical studies in the endodontic literature. There was a global interest in biochemical studies in the endodontic literature. This bibliometric analysis presented a comprehensive glance at the biochemical studies in the endodontic field and reported the importance of biochemistry for the endodontic literature.
Keywords: Bibliometric analysis; endodontics; biochemistry; biomarker
Amaç: Çalışmanın amacı, endodontideki biyokimyasal çalışmaları değerlendirmek için bibliyometrik analiz yapmaktır. Gereç ve Yöntemler: Elektronik arama, Web of Science veritabanında zaman sınırlaması olmadan 10 Ekim 2023 tarihine kadar gerçekleştirildi. Endodontideki biyokimya ile ilgili tüm makaleler dâhil edildi. Modülerlik Q indeksi, ortalama siluet ve merkezilik değerleri belirlendi. Yayın büyüme eğilimleri, alıntılar, anahtar kelimeler, ülkeler, dergiler ve yazarlar CiteSpace ve VOSviewer kullanılarak analiz edildi. Bulgular: Toplam 831 (754 orijinal makale ve 77 inceleme) çalışma analiz edildi. 1978-2023 yılları arasında ortalama büyüme oranı yaklaşık %10,13 olmuştur. İlk çalışma 1978 yılında yayınlanmıştır. Biyokimyasal konular 71 ülke tarafından çalışılmıştır ancak bunların başında ABD, Brezilya, Japonya ve Çin gelmektedir. Yayınlara toplam 3998 yazar katkıda bulunmuştur. Journal of Endodontics bu sayıdaki çalışmaların öncüsü oldu. Sonuç: Artan yayın eğilimi, endodonti literatüründe biyokimyasal çalışmalara olan ilginin arttığını göstermektedir. Biyokimyasal çalışmalara ilgi endodonti literatüründe küresel çapta gerçekleşmiştir. Bu bibliyometrik analiz endodonti alanındaki biyokimyasal çalışmalara kapsamlı bir bakış sundu. Bu çalışma endodonti literatürü için biyokimyanın önemini ortaya koymuştur.
Anahtar Kelimeler: Bibliyometrik analiz; endodonti; biyokimya; biyobelirteç
- Brizuela C, Meza G, Mercadé M, Inostroza C, Chaparro A, Bravo I, et al. Inflammatory biomarkers in dentinal fluid as an approach to molecular diagnostics in pulpitis. Int Endod J. 2020;53(9):1181-91. [Crossref] [PubMed]
- Donnermeyer D, Dammaschke T, Lipski M, Schäfer E. Effectiveness of diagnosing pulpitis: a systematic review. Int Endod J. 2023;56 Suppl 3:296-325. [Crossref] [PubMed]
- Džopalić T, Tomić S, Bekić M, Vučević D, Mihajlović D, Eraković M, et al. Ex vivo study of IL-6 expression and function in immune cell subsets from human periapical lesions. Int Endod J. 2022;55(5):480-94. [Crossref] [PubMed]
- Karrar RN, Cushley S, Duncan HF, Lundy FT, Abushouk SA, Clarke M, El-Karim IA. Molecular biomarkers for objective assessment of symptomatic pulpitis: a systematic review and meta-analysis. Int Endod J. 2023;56(10):1160-77. [Crossref] [PubMed]
- Edwards D, Bailey O, Stone SJ, Duncan H. How is carious pulp exposure and symptomatic irreversible pulpitis managed in UK primary dental care? Int Endod J. 2021;54(12):2256-75. [Crossref] [PubMed]
- Duncan HF, Cooper PR, Smith AJ. Dissecting dentine-pulp injury and wound healing responses: consequences for regenerative endodontics. Int Endod J. 2019;52(3):261-6. [Crossref] [PubMed]
- Al Natour B, Lundy FT, About I, Jeanneau C, Dombrowski Y, El Karim IA. Regulation of caries-induced pulp inflammation by NLRP3 inflammasome: a laboratory-based investigation. Int Endod J. 2023;56(2):193-202. [Crossref] [PubMed] [PMC]
- Bakhsh A, Moyes D, Proctor G, Mannocci F, Niazi SA. The impact of apical periodontitis, non-surgical root canal retreatment and periapical surgery on serum inflammatory biomarkers. Int Endod J. 2022;55(9):923-37. [Crossref] [PubMed] [PMC]
- Braz-Silva PH, Bergamini ML, Mardegan AP, De Rosa CS, Hasseus B, Jonasson P. Inflammatory profile of chronic apical periodontitis: a literature review. Acta Odontol Scand. 2019;77(3):173-80. [Crossref] [PubMed]
- Rechenberg DK, Galicia JC, Peters OA. Biological markers for pulpal inflammation: a systematic review. PLoS One. 2016;11(11):e0167289. [Crossref] [PubMed] [PMC]
- Araujo-Pires AC, Francisconi CF, Biguetti CC, Cavalla F, Aranha AM, Letra A, et al. Simultaneous analysis of T helper subsets (Th1, Th2, Th9, Th17, Th22, Tfh, Tr1 and Tregs) markers expression in periapical lesions reveals multiple cytokine clusters accountable for lesions activity and inactivity status. J Appl Oral Sci. 2014;22(4):336-46. [Crossref] [PubMed] [PMC]
- Elsalhy M, Azizieh F, Raghupathy R. Cytokines as diagnostic markers of pulpal inflammation. Int Endod J. 2013;46(6):573-80. [Crossref] [PubMed]
- Lee H, Bae A, Kim J, Kingsley K. differential effects of extracellular matrix glycoproteins fibronectin and laminin-5 on dental pulp stem cell phenotypes and responsiveness. J Funct Biomater. 2023;14(2):91. [Crossref] [PubMed] [PMC]
- Loureiro C, Buzalaf MAR, Moraes FRN, Ventura TMO, Pelá VT, Pessan JP, Jacinto RC. Quantitative proteomic analysis in symptomatic and asymptomatic apical periodontitis. Int Endod J. 2021;54(6):834-47. [Crossref] [PubMed]
- Montis N, Cotti E, Noto A, Fattuoni C, Barberini L. Salivary metabolomics fingerprint of chronic apical abscess with sinus tract: a pilot study. ScientificWorldJournal. 2019;2019:3162063. [Crossref] [PubMed] [PMC]
- Naruse H, Itoh S, Itoh Y, Kagioka T, Abe M, Hayashi M. The Wnt/β-catenin signaling pathway has a healing ability for periapical periodontitis. Sci Rep. 2021;11(1):19673. [Crossref] [PubMed] [PMC]
- Sakagami H, Nakatani S, Enomoto A, Ota S, Kaneko M, Sugimoto M, et al. Multi-omics analysis of anti-inflammatory action of alkaline extract of the leaves of Sasa sp. J Clin Med. 2021;10(10):2100. [Crossref] [PubMed] [PMC]
- Sharma R, Kumar V, Logani A, Chawla A, Mir RA, Sharma S, et al. Association between concentration of active MMP-9 in pulpal blood and pulpotomy outcome in permanent mature teeth with irreversible pulpitis - a preliminary study. Int Endod J. 2021;54(4):479-89. [Crossref] [PubMed]
- Sirin DA, Ozcelik F, Ersahan S, Pence HH. The importance of inflammatory biomarkers, IL-6 and PAPP-A, in the evaluation of asymptomatic apical periodontitis. Odontology. 2021;109(1):250-8. [Crossref] [PubMed]
- Wei XL, Luo L, Chen MZ, Zhou J, Lan BY, Ma XM, et al. Temporospatial expression of neuropeptide substance P in dental pulp stem cells during odontoblastic differentiation in vitro and reparative dentinogenesis in vivo. J Endod. 2023;49(3):276-85. [Crossref] [PubMed]
- Cai X, Gong P, Huang Y, Lin Y. Notch signalling pathway in tooth development and adult dental cells. Cell Prolif. 2011;44(6):495-507. [Crossref] [PubMed] [PMC]
- Cordeiro MM, Dong Z, Kaneko T, Zhang Z, Miyazawa M, Shi S, et al. Dental pulp tissue engineering with stem cells from exfoliated deciduous teeth. J Endod. 2008;34(8):962-9. [Crossref] [PubMed]
- Paino F, La Noce M, Giuliani A, De Rosa A, Mazzoni S, Laino L, et al. Human DPSCs fabricate vascularized woven bone tissue: a new tool in bone tissue engineering. Clin Sci (Lond). 2017;131(8):699-713. [Crossref] [PubMed] [PMC]
- Rezai Rad M, Hosseinpour S, Ye Q, Yao S. Dental Tissues originated stem cells for tissue regeneration. In: Moharamzadeh K, Walsh LJ, Hosseinpour S, eds. Regenerative Approaches in Dentistry: An Evidence-Based Perspective. 1st ed. Springer International Publishing; 2021. p.9-33. [Crossref]
- Adnan S, Ullah R. Top-cited articles in regenerative endodontics: a bibliometric analysis. J Endod. 2018;44(11):1650-64. [Crossref] [PubMed]
- Shamszadeh S, Asgary S, Nosrat A. Regenerative endodontics: a scientometric and bibliometric analysis. J Endod. 2019;45(3):272-80. [Crossref] [PubMed]
- Ahmad P, Elgamal HAM. Citation classics in the journal of endodontics and a comparative bibliometric analysis with the most downloaded articles in 2017 and 2018. J Endod. 2020;46(8):1042-51. [Crossref] [PubMed]
- Silva EJNL, Pinto KP, Ajuz NC, Sassone LM. Ten years of minimally invasive access cavities in endodontics: a bibliometric analysis of the 25 most-cited studies. Restor Dent Endod. 2021;46(3):e42. [Crossref] [PubMed] [PMC]
- Aksoy U, Küçük M, Versiani MA, Orhan K. Publication trends in micro-CT endodontic research: a bibliometric analysis over a 25-year period. Int Endod J. 2021;54(3):343-53. [Crossref] [PubMed]
- Ahmad P, Vincent Abbott P, Khursheed Alam M, Ahmed Asif J. A bibliometric analysis of the top 50 most cited articles published in the Dental Traumatology. Dent Traumatol. 2020;36(2):89-99. [Crossref] [PubMed]
- Tonelli SQ, de Toubes KS, Brabo Pereira AM, de Oliveira Miranda AC, Fernandes LL, Nunes E, et al. Dentinal microcracks induced by endodontic procedures: a scientometric and bibliometric analysis. J Conserv Dent. 2022;25(1):78-87. [Crossref] [PubMed] [PMC]
- Lazzari EP, Ranly DM, Walker WA. Biochemical effects of formocresol on bovine pulp tissue. Oral Surg Oral Med Oral Pathol. 1978;45(5):796-802. [Crossref] [PubMed]
- Xu Z, Zhu Y, Hu Y, Huang M, Xu F, Wang J. Bibliometric and visualized analysis of neuropathic pain using Web of Science and CiteSpace for the past 20 years. World Neurosurg. 2022;162:e21-e34. [Crossref] [PubMed]
- Ma W, Yang YB, Xie TT, Xu Y, Liu N, Mo XN. Cerebral small vessel disease: a bibliometric analysis. J Mol Neurosci. 2022;72(11):2345-59. [Crossref] [PubMed] [PMC]
.: Process List