Turkiye Klinikleri Journal of Ophthalmology

.: ORIGINAL RESEARCH
Bilateral Brown Sendromunda Spontan İyileşme Gösteren ve Cerrahi Uygulanan Hastalardaki Klinik Faktörler
Clinical Factors in Patients with Bilateral Brown Syndrome Who Had Spontaneous Resolution and Undurwent Surgery
Burcu KEMER ATİKa, Osman Bulut OCAKa, Aslı İNALa, Ebru Demet AYGITa, Ceren GÜREZa, Gizem KUTLUTÜRKa, Muhittin TAŞKAPILIa, Birsen GÖKYİĞİTa
aGöz Hastalıkları Kliniği, Sağlık Bilimleri Üniversitesi Prof. Dr. N. Reşat Belger Beyoğlu Göz Eğitim ve Araştırma Hastanesi, İstanbul, TÜRKİYE
Turkiye Klinikleri J Ophthalmol. 2019;28(4):225-31
doi: 10.5336/ophthal.2018-63816
Article Language: TR
Full Text
ÖZET
 Amaç: Bilateral konjenital Brown sendromunda, spontan iyileşme gösteren ve cerrahi uygulanan hastaların klinik özelliklerinin değerlendirilmesidir. Gereç ve Yöntemler: Hastanemiz şaşılık biriminde konjenital Brown sendromu tanısı ile takip edilen hastalar retrospektif olarak değerlendirildi. En az 24 ay takip edilen bilateral konjenital Brown sendromu tanılı hastalar çalışmaya dâhil edildi. Hastaların; başvuru, 12. ve 24. ay, son kontrol muayenelerindeki oküler motilite kısıtlılığı seviyesi, vertikal kayma (VK) değerleri, anormal baş pozisyonu (ABP) ve stereopsis varlığı değerlendirildi. Hastalar Grup 1: Spontan iyileşme gösterenler, Grup 2: Cerrahi uygulananlar olarak iki gruba ayrıldı. İki grubun klinik özellikleri istatistiksel olarak karşılaştırıldı (Mann-Whitney U testi). Bulgular: Çalışmaya 16 bilateral Brown sendromu hastası dâhil edildi. Tüm hastaların ilk muayene yaşı ortalama 6,62±5,17 yıl idi. Brown sendromu başvuru yaşı Grup 1' de, Grup 2'den daha küçük bulundu (Grup 1: 3,62±2,50 yıl, Grup 2: 9,62±5,52 yıl). İlk muayenede, iki grup arası ABP varlığı ve VK ortalamaları açısından istatistiksel olarak anlamlı fark yoktu (sırasıyla; p=0,63, p=0,68). Son takip muayenesinde saptanan stereopsis pozitifliği Grup 1 hastalarında istatistiksel olarak daha anlamlı olarak yüksek idi (p=0,01). Sonuç: Konjenital bilateral Brown sendromu hastalarında, başlangıç ABP varlığının ve VK ölçüm değerlerinin spontan iyileşme üzerine istatistiksel anlamlı etkisi bulunmamıştır. Bununla birlikte, spontan iyileşme gözlenen hastalarda, son muayenedeki stereopsis varlığı anlamlı olarak daha yüksek bulunmuştur.

Anahtar Kelimeler: Şaşılık; Brown sendromu; göz hareket bozuklukları
ABSTRACT
 Objective: To evaluate the clinical features of patients with bilateral congenital Brown syndrome who had spontaneous resolution and underwent surgery. Material and Methods: The patients with the diagnosis congenital Brown syndrome who were followed up in our hospital strabismus department were retrospectively reviewed. The patients with the diagnosis bilateral congenital Brown syndrome with follow-up time at least 24 months were included this study. Limitations of ocular motility, vertical deviations (VD), presence of abnormal head position (AHP) and stereopsis were evaluated at first, 12th month, 24th month and last follow-up examinations, respectively. Patients were divided into two groups: Group 1: The patients who had spontaneous resolution and Group 2: The patients who were performed strabismus surgery. The clinical characteristics of these two groups were statistically compared (Mann-Whitney U test). Results: Sixteen patients with bilateral Brown syndrome patients were included in this study. The mean age was 6.62±5.17 years at first examination. The mean age of first exam of Brown syndrome in Group 1 was smaller than those in Group 2 (Group 1: 3.62±2.50 years, Group 2: 9.62±5.52 years). There was no statistically significant difference between the two groups in terms of the presence of ABP and VD amounts in the first examination (p=0.63, p=0.68, respectively). The presence of stereopsis was found to be statistically significantly higher in Group 1 (p=0.01). Conclusion: Presence of initial ABP and VD amounts don't have a significant effect on spontaneous resolution in congenital bilateral Brown syndrome. Furthermore, the presence of stereopsis in the final examination was found to be significantly higher in the cases with spontaneous resolution.

Keywords: Strabismus; Brown syndrome; ocular motility disorders
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