Turkiye Klinikleri Journal of Medical Sciences

.: ORIGINAL RESEARCH
Bibliometric Analysis of miRNA Studies in the Field of Biophysics: Descriptive Study
Biyofizik Alanında miRNA Çalışmalarının Bibliyometrik Analizi: Tanımlayıcı Çalışma
Yasemin BERBEROĞLUa , Yasemin ADALIa,b, Veli Kaan AYDINa , Aylin KÖSELERa
aPamukkale University Faculty of Medicine, Department of Biophysics, Denizli, Türkiye
bQueen's University Belfast, Faculty of Medicine, Department of Dentistry and Biomedical Sciences, Belfast, United Kingdom
Turkiye Klinikleri J Med Sci. 2025;45(3):121-9
doi: 10.5336/medsci.2025-108255
Article Language: EN
Full Text
ABSTRACT
 Objective: MicroRNAs (miRNAs) are small endogenous post-transcriptional regulators of gene expression found in eukaryotes. With Victor Ambros and Gary Ruvkun receiving the 2024 Nobel Prize, studies on miRNAs are expected to increase. The purpose of the bibliometric analysis is to determine the effectiveness of studies conducted in the field of biophysics on miRNAs. Material and Methods: The data collected from the Web of Science Core Collection (WoSCC) and advance search was conducted using keywords: ''Micro RNA OR RNA, Micro OR MicroRNA OR miRNA* OR RNA, Small Temporal OR Temporal RNA, Small OR Small Temporal RNA OR stRNA OR Primary MicroRNA OR MicroRNA, Primary OR primiRNA OR pri miRNA OR Primary miRNA OR miRNA, Primary OR pre-miRNA OR pre miRNA*''. Biophysics was selected among WoS Categories. As a result of these inclusion criteria, 3,369 documents. Among these documents, the first 500 articles were taken according to their relevance ranking. All bibliographic data were exported from the WoSCC database and analyzed using analytical bibliometric methods. Results: The annual growth rate between 1988-2025 was 1.89%. The number of articles increased exponentially after 2005. The most published source of articles on miRNAs in the Biophysics category is ''Biochemical and Biophysical Research Communications''. The affiliation with the most articles is Wuhan University in China. Recent trend topics are the keywords plus words ''de-novo prediction, model, injury''. Conclusion: This study is important in terms of analyzing studies on miRNAs in the field of biophysics and guiding future studies.

Keywords: MicroRNAs; biophysics; bibliometrics
ÖZET
 Amaç: MikroRNA'lar (miRNA'lar), ökaryotlarda bulunan gen ifadesinin küçük endojen transkripsiyon sonrası düzenleyicileridir. Victor Ambros ve Gary Ruvkun'un 2024 Nobel Ödülü'nü almasıyla, miRNA'lar üzerine yapılan çalışmaların artması bekleniyor. Bibliyometrik analizin amacı, biyofizik alanında yapılan çalışmaların miRNA'lar üzerindeki etkinliğini belirlemektir. Gereç ve Yöntemler: Web of Science Core Collection'dan (WoSCC) toplanan veriler ve gelişmiş arama, şu anahtar sözcükler kullanılarak yapıldı: ''Micro RNA OR RNA, Micro OR MicroRNA OR miRNA* OR RNA, Small Temporal OR Temporal RNA, Small OR Small Temporal RNA OR stRNA OR Primary MicroRNA OR MicroRNA, Primary OR pri-miRNA OR pri miRNA OR Primary miRNA OR miRNA, Primary OR pre-miRNA OR pre miRNA*''. Biyofizik, WoS Kategorileri arasından seçildi. Bu dâhil etme kriterlerinin bir sonucu olarak, 3.369 belge bulundu. Bu belgeler arasında, ilk 500 makale ilgililik sıralamasına göre alındı. Tüm bibliyografik veriler WoSCC veritabanından dışa aktarıldı ve analitik bibliyometrik yöntemler kullanılarak analiz edildi. Bulgular: 1988-2025 arasındaki yıllık büyüme oranı %1,89'du. Makale sayısı 2005'ten sonra katlanarak arttı. Biyofizik kategorisinde miRNA'lar hakkında en çok yayınlanan makale kaynağı ''Biochemical and Biophysical Research Communications''dır. En fazla makaleye sahip olan kuruluş, Çin'deki Wuhan Üniversitesi'dir. Son trend topic kelimeler ''de-novo prediction, model, injury'' kelimeleridir. Sonuç: Bu çalışma, biyofizik alanında miRNA'lar üzerine yapılan çalışmaları analiz etmek ve gelecekteki çalışmalara rehberlik etmek açısından önemlidir.

Anahtar Kelimeler: MikroRNAlar; biyofizik; bibliyometri
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