Turkiye Klinikleri Journal of Medical Sciences

.: ORIGINAL RESEARCH
Benign/Malign Primer Sakrum Tümörleri ve Cerrahi Alan Enfeksiyonlarının Değerlendirilmesi
Evaluation of Benign/Malign Primary Sacrum Tumors and Surgical Site Infections
Anıl Murat ÖZTÜRKa, Deniz AKYOLb, Onur SÜERa, Burçin KEÇECİa, Dündar SABAHa, Meltem IŞIKGÖZ TAŞBAKANb
aOrtopedi ve Travmatoloji AD,
bEnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji AD, Ege Üniversitesi Tıp Fakültesi, İzmir, TÜRKİYE
Turkiye Klinikleri J Med Sci. 2018;38(4):309-16
doi: 10.5336/medsci.2018-60724
Article Language: TR
Full Text
ÖZET
Amaç: Literatürde sakrum tümörü ve cerrahisi oldukça azdır. Sakrumun primer tümörleri metastatik tümörlere göre daha seyrek görülmektedir. Bu çalışmada benign/malign primer sakrum tümörü nedeni ile ameliyat edilmiş olguların özellikleri ve operasyon sonrası ortaya çıkan cerrahi alan enfeksiyonların değerlendirilmesi amaçlanmıştır. Gereç ve Yöntemler: Hastanemiz Ortopedi kliniğinde 2012- 2018 yılları arasında patolojik inceleme ile benign/malign primer sakrum tümörü tanısı alan ve cerrahi tedavi uygulanan olguların kayıtları retrospektif olarak incelenmiştir. Olguların demografik özellikleri, komorbid hastalıkları, cerrahi ve medikal tedavi modelleri, cerrahi alan enfeksiyon sıklığı, operasyon sonrası yara yeri özellikleri, olguların vital bulguları, enfeksiyon gelişme süresi, enfeksiyon etkeni olan mikroorganizmalar, reenfeksiyon etkenleri, gelişme sıklığı, süresi ve 5 yıllık sağkalımları açısından retrospektif olarak incelenmiştir. Bulgular: Toplam 9 olgu, [beş erkek, dört kadın, ortalama yaş 38 yıl (21-74)] dahil edilmiştir. Patolojik inceleme ile 9 olgunun 3'ü (%33,3) kordoma, 3'ü (%33,3) ewing sarkom, biri (%11,1) malign schwannom, biri (%11,1) dev hücreli tümör ve biri (%11,1) kondrosarkom tanısı almıştır. Malign tümör tanılı 8 olgunun (%88,9) 6'sına geniş rezeksiyon bir olguya (%11,1) benign tümör tanısı ile intralezyonel küretaj uygulanmıştır. Olguların 6'sında (%66,7) operasyon sonrası cerrahi alan enfeksiyonu gelişmiştir. Pre-op ve/veya post-op radyoterapi ve kemoterapi alan olguların 3'ünde (%75) enfeksiyon saptanırken, operasyonda implantasyon kullananılanların tamamında operasyon sonrası enfeksiyon ortaya çıkmıştır. Tüm olgularda 5 yıllık sağkalım %77,7, cerrahi alan enfeksiyonu gelişenlerde ise %83,3 bulunmuştur. Sonuç: Sakrektomi gibi geniş rezeksiyon yapılan ve rektuma yakın komşuluğu olan operasyonlar sonrasında enfeksiyonlar sık karşılaşılan bir problemdir. Cerrahi alan enfeksiyonu tedavisinde cerrahi debritman ve etkene yönelik antibiyoterapinin birlikte uygulanması da ayrıca önem taşımaktadır.

Anahtar Kelimeler: Sakrum tümörleri; cerrahi alan enfeksiyonu
ABSTRACT
Objective: In literature, sacrum tumors and its surgery are very few. Primary tumors of sacrum are less common than metastatic tumors. In this study, it was aimed to evaluate the characteristics and the surgical site infections after surgery of the cases operated with benign/malign primer sacrum tumor. Material and Methods: We retrospectively reviewed records of cases of operated with diagnosed by pathological examination benign/malign primer sacrum tumors in our clinic between the years of 2012 and 2018. The demographic characteristics of the cases, comorbid diseases, applied surgical treatment modalities, post-operative surgical site infection frequency, post operative features of wound site, vital findings of cases, duration of post-operative infection development, causative microorganism agents in infection, the incidence, duration and causative microorganism of recurrent infections and the survival for five years were evaluated. Results: A total of 9 cases [five male, four female, mean age 38 years (21-74)] were included. 3 cases (33,3%) were cordoma, 3 cases (33,3%) were ewing sarcoma, one case (11,1%) malignant schwannom, one case (11,1%) giant cell tumor and one case (11,1%) were diagnosed with chondrosarcoma in their pathological examinations. Eight patients (88.9%) with malign tumor underwent extensive resection in 6 patients and one patient (11.1%) with intralesional curettage with benign tumor diagnosis. Six of the cases (66.7%) developed surgical site infection after the surgery. Infection was detected in 3 (75%) of the cases who recieved the pre-op and/or post-op radiotherapy and chemotherapy but in all underwent implantation during the surgery. Overall survival was 77.7% at 5 years and 83.3% in who developed surgical site infection. Conclusion: As in the sacrectomy, infections after operations in the operations with extensive resection and close rectal proximity are common problems. Besides antibiotic therapy co-administration of surgical debridement is also important for efficacy in the treatment of surgical site infection.

Keywords: Sacrum tumors; surgical site infection

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