Turkiye Klinikleri Journal of Dental Sciences

.: ORIGINAL RESEARCH
Awareness of Medication Related Osteonecrosıs of the Jaw among Dentist Working at Public Oral and Dental Health Care Centers in Ankara, Turkey
Türkiye, Ankara'da Kamu Ağız ve Diş Sağlığı Merkezlerinde Çalışan Diş Hekimleri Arasında Çenenin İlaçla İlişkili Osteonekrozu Farkındalığı
Ömer EKİCİa
aDepartment of Oral and Maxillofacial Surgery, Afyonkarahisar Health Sciences University Faculty of Dentistry, Afyonkarahisar, TURKEY
Turkiye Klinikleri J Dental Sci.2021;27(1):98-107
doi: 10.5336/dentalsci.2020-74342
Article Language: EN
Full Text
ABSTRACT
 Objective: Medication related osteonecrosis of the jaw (MRONJ) is a major complication of treatment with antiresorptive and antiangiogenic agents in the oral and maxillofacial region. This cross-sectional study aims to evaluate knowledge and awareness about MRONJ among dentists working in Ankara, Turkey. Material and Methods: A cross-sectional survey was carried out among dentists working at public oral and dental health care centers in Ankara. A questionnaire was designed to seek information about dentists' demographic characteristics, their knowledge of the term 'MRONJ', of drugs that cause jaw osteonecrosis, of the risk factors of MRONJ and their attitudes and practices regarding MRONJ. A total of 325 dentists participated in the study. Results: More than half of the dentists in this study were unable to define osteonecrosis of the jaw. Most (61.2%) were able to identify bisphosphonates associated with MRONJ, but about 80% were unaware of antiangiogenic drugs and 93.5% of nuclear factor kappa B ligand inhibitors. Most dentists in the study were unaware of most of the main risk factors for MRONJ. Thirty-six percent of the dentists had received MRONJ training during their undergraduate education, but only 5.2% had been trained in the last five years. Conclusion: This study highlights a huge lack of knowledge and awareness about MRONJ among dentists in Turkey. There is a need to provide further education and training in order to improve dentists' awareness of bisphosphonates and other medications that have the potential to cause osteonecrosis. Education of healthcare professionals and multidisciplinary cooperation can potentially improve patient safety and reduce the risk of developing MRONJ.

Keywords: Medication related osteonecrosis of the jaw; antiresorptive drugs; antiangiogenic drugs; dentists
ÖZET
 Amaç: Çenenin ilaca bağlı osteonekrozu (MRONJ), oral ve maksillofasiyal bölgede antirezorptif ve antianjiyojenik ajanlarla tedavinin önemli bir komplikasyonudur. Bu kesitsel çalışma Türkiye, Ankara'daki diş hekimleri arasındaki MRONJ bilgi ve farkındalığını değerlendirmeyi amaçlamaktadır. Gereç ve Yöntemler: Ankara'da, kamu ağız ve diş sağlığı merkezlerinde çalışan diş hekimleri arasında kesitsel bir anket yapılmıştır. Diş hekimlerinin demografik özellikleri, 'MRONJ' terimi, çene osteonekrozuna neden olan ilaçlar, MRONJ risk faktörleri, MRONJ ile ilgili tutum ve uygulamaları hakkında bilgi edinmek amacıyla bir anket tasarlanmıştır. Çalışmaya, toplam 325 diş hekimi katılmıştır. Bulgular: Bu çalışmada, diş hekimlerinin yarısından fazlası çenenin osteonekrozunu tanımlayamamıştır. Çoğu (%61,2) MRONJ ile ilişkili bifosfonatları tanımlayabilmiştir, ancak yaklaşık %80'i antianjiyojenik ilaçlardan ve %93,5'i nükleer faktör kappa B ligand inhibitörlerinden habersizdi. Çalışmada çoğu diş hekimi, MRONJ için ana risk faktörlerinin çoğunun farkında değildi. Diş hekimlerinin %36'sı lisans eğitimi sırasında MRONJ eğitimi almıştır, ancak son 5 yılda sadece %5,2'si eğitim almıştır. Sonuç: Bu çalışma, Türkiye'deki diş hekimleri arasında MRONJ hakkında büyük bir bilgi ve farkındalık eksikliğini vurgulamaktadır. Diş hekimlerinin, bisfosfonatlar ve çene nekrozuna neden olma potansiyeli olan diğer ilaçlarla ilgili farkındalıklarını artırmak için daha fazla eğitim ve öğretime ihtiyaç vardır. Sağlık profesyonellerinin eğitimi ve multidisipliner iş birliği potansiyel olarak hasta güvenliğini artırabilir ve MRONJ gelişme riskini azaltabilir.

Anahtar Kelimeler: Çenenin ilaçlarla ilişkili osteonekrozu; antiresorptif ilaçlar; antianjiyogenik ilaçlar; diş hekimleri
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